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Biases in electronic health record data due to processes within the healthcare system: retrospective observational study. High-depth whole genome sequencing of an Ashkenazi Jewish reference panel: enhancing sensitivity, accuracy, and imputation.

Analyzing user interactions with biomedical ontologies: A visual perspective. International Semantic Web Conference International Semantic Web Conference. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. Experimental maps of DNA structure at nucleotide resolution distinguish intrinsic from protein-induced DNA deformations.

Investigating the association between parity and the maternal neural response to infant cues. Medical subdomain classification of clinical notes using a machine learning-based natural language processing approach. Enabling phenotypic big data with PheNorm. Temporal Annotation in the Clinical Domain. Mechanisms to protect the privacy of families when using the transmission disequilibrium test in genome-wide association studies.

Segment convolutional neural networks Seg-CNNs for classifying relations in clinical notes. Biological and functional relevance of CASP predictions.

Genome wide in vivo mouse screen data from studies to assess host regulation of metastatic colonisation. Genome-wide association analysis identifies common variants influencing infant brain volumes. OpenMM 7: Rapid development of high performance algorithms for molecular dynamics.

Simulating ideal assistive devices to reduce the metabolic cost of walking with heavy loads. Recurrent neural networks for classifying relations in clinical notes. Effects of Alcohol on Human Aggression. How Do You relax When You're stressed? An empirical analysis of ontology reuse in BioPortal. ShapeCut: Bayesian surface estimation using shape-driven graph. Age-Related Autonomous Aldosteronism. Geodesic shape regression with multiple geometries and sparse parameters.

Robust automated constellation-based landmark detection in human brain imaging. Combining clinical and genomics queries using i2b2 - Three methods. Genetic effects influencing risk for major depressive disorder in China and Europe.

Addressing Beacon re-identification attacks: quantification and mitigation of privacy risks. Neural circuitry at age 6 months associated with later repetitive behavior and sensory responsiveness in autism. Early brain development in infants at high risk for autism spectrum disorder. Preparatory co-activation of the ankle muscles may prevent ankle inversion injuries.

Genome-wide in vivo screen identifies novel host regulators of metastatic colonization. Mechanical characterization of human brain tissue.

Integrative analysis of genetic data sets reveals a shared innate immune component in autism spectrum disorder and its co-morbidities. Exploring the neural substrates of attentional control and human intelligence: Diffusion tensor imaging of prefrontal white matter tractography in healthy cognition.

Multimodal neuroimaging computing: the workflows, methods, and platforms. Multimodal neuroimaging computing: a review of the applications in neuropsychiatric disorders. Twin-singleton developmental study of brain white matter anatomy. Protecting genomic data analytics in the cloud: state of the art and opportunities.

Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism. Genome privacy: challenges, technical approaches to mitigate risk, and ethical considerations in the United States. Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood. Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode.

Differences in GlycA and lipoprotein particle parameters may help distinguish acute kawasaki disease from other febrile illnesses in children. Making a meaningful impact: modelling simultaneous frictional collisions in spatial multibody systems. Genetic Misdiagnoses and the Potential for Health Disparities. Transition path theory analysis of c-Src kinase activation. Immune DNA signature of T-cell infiltration in breast tumor exomes.

Longitudinal modeling of appearance and shape and its potential for clinical use. Functional characterization of somatic mutations in cancer using network-based inference of protein activity.

Antenatal depression, treatment with selective serotonin reuptake inhibitors, and neonatal brain structure: A propensity-matched cohort study. Parental reflective functioning and the neural correlates of processing infant affective cues. Learning statistical models of phenotypes using noisy labeled training data. Common 3-dimensional coordinate system for assessment of directional changes.

American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics. Discovery of a regioselectivity switch in nitrating Ps guided by molecular dynamics simulations and Markov models.

Single-index varying coefficient model for functional responses. Webulous and the Webulous Google Add-On--a web service and application for ontology building from templates.

Conformational heterogeneity of the calmodulin binding interface. Tensor factorization toward precision medicine. Utilizing a structural meta-ontology for family-based quality assurance of the BioPortal ontologies. Proceedings of the Non-Euclidean classification of medically imaged objects via s-reps. Semi-supervised Learning for Phenotyping Tasks. Probabilistic Modeling of Imaging, Genetics and Diagnosis.

Is the crowd better as an assistant or a replacement in ontology engineering? An exploration through the lens of the Gene Ontology.

Ten Simple Rules for Selecting a Bio-ontology. Bridging semantics and syntax with graph algorithms-state-of-the-art of extracting biomedical relations. Genes with monoallelic expression contribute disproportionately to genetic diversity in humans.

Biomechanical model for computing deformations for whole-body image registration: A meshless approach. Generating Purkinje networks in the human heart. Privacy-preserving GWAS analysis on federated genomic datasets. Absence of evidence for increase in risk for autism or attention-deficit hyperactivity disorder following antidepressant exposure during pregnancy: a replication study. Predictive modeling of risk factors and complications of cataract surgery.

Identification of significantly mutated regions across cancer types highlights a rich landscape of functional molecular alterations. Entropy-based particle correspondence for shape populations. Comparing high-dimensional confounder control methods for rapid cohort studies from electronic health records. Splicing Express: a software suite for alternative splicing analysis using next-generation sequencing data.

Rapid identification of slow healing wounds. Inter- and intra-patient clonal and subclonal heterogeneity of chronic lymphocytic leukaemia: evidences from circulating and lymph nodal compartments. Three-dimensional regional displacement after surgical-orthodontic correction of Class III malocclusion. Multilayered temporal modeling for the clinical domain. Data Compression Conference. Splenium development and early spoken language in human infants.

Implications of non-stationarity on predictive modeling using EHRs. Expression Atlas update--an integrated database of gene and protein expression in humans, animals and plants. Creation of a new longitudinal corpus of clinical narratives. Bayesian network analysis of multi-compartmentalized immune responses in a murine model of sepsis and direct lung injury. The digital revolution in phenotyping. A gene expression resource generated by genome-wide lacZ profiling in the mouse.

Expanded genetic screening panel for the Ashkenazi Jewish population. Galectin-3 is a marker of myocardial and vascular fibrosis in Kawasaki disease patients with giant aneurysms. Ranking Medical Subject Headings using a factor graph model. Abnormal white matter connections between medial frontal regions predict symptoms in patients with first episode schizophrenia. Keypoint Transfer Segmentation. Analysis of the volumetric relationship among human ocular, orbital and fronto-occipital cortical morphology.

Novel data-mining approach identifies biomarkers for diagnosis of Kawasaki disease. Depressive symptoms related to low fractional anisotropy of white matter underlying the right ventral anterior cingulate in older adults with atherosclerotic vascular disease.

Preliminary analysis using multi-atlas labeling algorithms for tracing longitudinal change. A method for systematic discovery of adverse drug events from clinical notes. Ease of adoption of clinical natural language processing software: An evaluation of five systems.

Assigning and visualizing germline genes in antibody repertoires. Prefrontal cortex white matter tracts in prodromal Huntington disease. Automated generation of directed graphs from vascular segmentations. United polarizable multipole water model for molecular mechanics simulation.

The Regulatory Machinery of Neurodegeneration in In?? Vitro Models of Amyotrophic Lateral Sclerosis. A system to build distributed multivariate models and manage disparate data sharing policies: implementation in the scalable national network for effectiveness research.

Convex Clustering with Exemplar-Based Models. Robust estimation of group-wise cortical correspondence with an application to macaque and human neuroimaging studies.

Towards measuring neuroimage misalignment. ABC transporters and the proteasome complex are implicated in susceptibility to Stevens-Johnson syndrome and toxic epidermal necrolysis across multiple drugs. The immunomodulatory effects of intravenous immunoglobulin therapy in Kawasaki disease.

What Data to Co-register for Computing Atlases. A network of molecular switches controls the activation of the two-component response regulator NtrC. Contour-Driven Atlas-Based Segmentation. Direct ChIP-Seq significance analysis improves target prediction.

A diffusion tensor MRI atlas of the postmortem rhesus macaque brain. Affine Registration of label maps in Label Space. Shape index distribution based local surface complexity applied to the human cortex. Annotating risk factors for heart disease in clinical narratives for diabetic patients. Building the graph of medicine from millions of clinical narratives.

Federated queries of clinical data repositories: Scaling to a national network. Sharing my health data: a survey of data sharing preferences of healthy individuals. Trends in publication of nursing informatics research. An information theoretic method to identify combinations of genomic alterations that promote glioblastoma.

Altered corpus callosum morphology associated with autism over the first 2 years of life. Bacterial division. Mechanical crack propagation drives millisecond daughter cell separation in Staphylococcus aureus. Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources. Genetic similarity between cancers and comorbid Mendelian diseases identifies candidate driver genes. The association between lower educational attainment and depression owing to shared genetic effects?

Development of phenotype algorithms using electronic medical records and incorporating natural language processing. Statistical inference for nanopore sequencing with a biased random walk model. OpenSim: a musculoskeletal modeling and simulation framework for in silico investigations and exchange. BAP1 mutation is a frequent somatic event in peritoneal malignant mesothelioma.

Identifying candidate drivers of alcohol dependence-induced excessive drinking by assembly and interrogation of brain-specific regulatory networks. Grid multi-category response logistic models. Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma. Normalization of relative and incomplete temporal expressions in clinical narratives. Simbody: multibody dynamics for biomedical research.

Diabetes and the risk of infections with immunomodulator therapy in inflammatory bowel diseases. Neuroinformatics and the The Insight ToolKit. Role of TGF-? Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. Development of a web service for analysis in a distributed network. Predictive simulation generates human adaptations during loaded and inclined walking.

Comparison of consumers' views on electronic data sharing for healthcare and research. Variations in the binding pocket of an inhibitor of the bacterial division protein FtsZ across genotypes and species. Ranking adverse drug reactions with crowdsourcing. Cardiovascular pathology in 2 young adults with sudden, unexpected death due to coronary aneurysms from Kawasaki disease in childhood.

Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression. Quantitative modeling of transcription factor binding specificities using DNA shape. Transient pairing of homologous Oct4 alleles accompanies the onset of embryonic stem cell differentiation. Running with a load increases leg stiffness. Patient-specific biomechanical model as whole-body CT image registration tool.

Gene-wide identification of episodic selection. Less is more: an adaptive branch-site random effects model for efficient detection of episodic diversifying selection. Template-based prediction of protein function. Gene interactions and structural brain change in early-onset Alzheimer's disease subjects using the pipeline environment. Geodesic image regression with a sparse parameterization of diffeomorphisms. Geometric Science of Information 1st : : Paris, France.

Identification of rare germline copy number variations over-represented in five human cancer types. A time-indexed reference standard of adverse drug reactions. Comparing 3T and 1. BrainPrint: a discriminative characterization of brain morphology. Cloud computing approaches for prediction of ligand binding poses and pathways.

Analyzing search behavior of healthcare professionals for drug safety surveillance. Single-molecule dataset SMD : a generalized storage format for raw and processed single-molecule data.

Overcome support vector machine diagnosis overfitting. A novel genome-wide significant locus on chromosome 2 near ASB3. Medial frontal white and gray matter contributions to general intelligence. Epileptogenic focus localization in treatment-resistant post-traumatic epilepsy.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. RELAX: detecting relaxed selection in a phylogenetic framework. Genotype to phenotype relationships in autism spectrum disorders. Scalable privacy-preserving data sharing methodology for genome-wide association studies: an application to iDASH healthcare privacy protection challenge.

Differentially private genome data dissemination through top-down specialization. A community assessment of privacy preserving techniques for human genomes. Longitudinal quantification and visualization of intracerebral haemorrhage using multimodal magnetic resonance and diffusion tensor imaging.

Segmentation of cerebrovascular pathologies in stroke patients with spatial and shape priors. Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia.

Is my model good enough? Best practices for verification and validation of musculoskeletal models and simulations of movement. Multi-modal robust inverse-consistent linear registration.

Differences in muscle activity between natural forefoot and rearfoot strikers during running. Integration of genomic data enables selective discovery of breast cancer drivers.

Comment on: ''Zoo or savannah? Choice of training ground for evidence-based pharmacovigilance''. Multimodal neuroimaging feature learning for multiclass diagnosis of Alzheimer's disease. A community computational challenge to predict the activity of pairs of compounds. Discovering chemistry with an ab initio nanoreactor. Text mining in cancer gene and pathway prioritization. Statistical estimation of physiological brain age as a descriptor of senescence rate during adulthood.

Long-term phenotypic evolution of bacteria. The genetic basis of chronic mountain sickness. ArrayExpress update--simplifying data submissions. Choosing blindly but wisely: differentially private solicitation of DNA datasets for disease marker discovery.

Disease Ontology update: an expanded and updated database of human diseases for linking biomedical knowledge through disease data. Automatic identification of methotrexate-induced liver toxicity in patients with rheumatoid arthritis from the electronic medical record. Computational modeling of hypertensive growth in the human carotid artery. Systems biology. Conditional density-based analysis of T cell signaling in single-cell data.

The DTI connectivity of the human claustrum. Functional evaluation of out-of-the-box text-mining tools for data-mining tasks.

Interrogation of a context-specific transcription factor network identifies novel regulators of pluripotency. Atlas-based under-segmentation. Gaussian process interpolation for uncertainty estimation in image registration. Diffeomorphic shape trajectories for improved longitudinal segmentation and statistics. BrainPrint: identifying subjects by their brain. Subject-specific prediction using nonlinear population modeling: application to early brain maturation from DTI. Hierarchical bayesian modeling, estimation, and sampling for multigroup shape analysis.

Evolving insights on how cytosine methylation affects protein-DNA binding. Inferring protein modulation from gene expression data using conditional mutual information. Cingulum bundle integrity associated with delusions of control in schizophrenia: Preliminary evidence from diffusion-tensor tractography. Characterizing growth patterns in longitudinal MRI using image contrast.

Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks. International Conference on Machine Learning. Predicting accurate probabilities with a ranking loss. Machine learning : proceedings of the International Conference. Abstractions for Genomics. The Living Heart Project: A robust and integrative simulator for human heart function.

Multivariate longitudinal shape analysis of human lateral ventricles during the first twenty-four months of life. IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform. Computational modeling of skin: Using stress profiles as predictor for tissue necrosis in reconstructive surgery. Mode of childbirth and long-term outcomes in women with inflammatory bowel diseases. Co-regulated transcripts associated to cooperating eSNPs define Bi-fan motifs in human gene networks.

Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins. The role of mechanics during brain development. Use it or lose it: multiscale skeletal muscle adaptation to mechanical stimuli. Sparse kernel machine regression for ordinal outcomes. Pegasus: a comprehensive annotation and prediction tool for detection of driver gene fusions in cancer. Decoupling function and anatomy in atlases of functional connectivity patterns: language mapping in tumor patients.

Comparative analysis of metazoan chromatin organization. In search of the determinants of enhancer-promoter interaction specificity.

Prenatal antidepressant exposure is associated with risk for attention-deficit hyperactivity disorder but not autism spectrum disorder in a large health system. SELEX-seq: a method for characterizing the complete repertoire of binding site preferences for transcription factor complexes.

Complex pathways in folding of protein G explored by simulation and experiment. Evolution of the central sulcus morphology in primates. Treatment selections using risk-benefit profiles based on data from comparative randomized clinical trials with multiple endpoints. Multiple LacI-mediated loops revealed by Bayesian statistics and tethered particle motion. Classification of CT pulmonary angiography reports by presence, chronicity, and location of pulmonary embolism with natural language processing.

Differentially private distributed logistic regression using private and public data. Data-driven discovery of seasonally linked diseases from an Electronic Health Records system. Multi-atlas segmentation with particle-based group-wise image registration. Impact of family history on prostate cancer mortality in white men undergoing prostate specific antigen based screening. Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records.

Lipoprotein particle concentrations in children and adults following Kawasaki disease. An autism case history to review the systematic analysis of large-scale data to refine the diagnosis and treatment of neuropsychiatric disorders. Robust Radiomics feature quantification using semiautomatic volumetric segmentation. Characterization of living skin using multi-view stereo and isogeometric analysis.

Privacy preserving RBF kernel support vector machine. A mechanical model predicts morphological abnormalities in the developing human brain. Localized abnormalities in the cingulum bundle in patients with schizophrenia: a Diffusion Tensor tractography study. Prenatal cocaine effects on brain structure in early infancy. Toward personalizing treatment for depression: predicting diagnosis and severity. ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2.

Morphometry of anatomical shape complexes with dense deformations and sparse parameters. Characterizing a collective and dynamic component of chromatin immunoprecipitation enrichment profiles in yeast. The elusive evidence for chromothripsis. Harnessing natural sequence variation to dissect posttranscriptional regulatory networks in yeast. Multi-Channel neurodegenerative pattern analysis and its application in Alzheimer's disease characterization.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. Inferring gene ontologies from pairwise similarity data.

Dysmorphogenic effects of first trimester-equivalent ethanol exposure in mice: a magnetic resonance microscopy-based study. Fluoroquinolone resistant rectal colonization predicts risk of infectious complications after transrectal prostate biopsy.

Integrative biology identifies shared transcriptional networks in CKD. OpenIGTLink interface for state control and visualisation of a robot for image-guided therapy systems. MAGI: a Node. Structural bioinformatics of the interactome. A community effort to assess and improve drug sensitivity prediction algorithms.

Natural language processing in biomedicine: a unified system architecture overview. Evaluating the effects of machine pre-annotation and an interactive annotation interface on manual de-identification of clinical text.

Transfer learning based clinical concept extraction on data from multiple sources. Structural and connectomic neuroimaging for the personalized study of longitudinal alterations in cortical shape, thickness and connectivity after traumatic brain injury.

Meshless Modeling of Deformable Shapes and their Motion. Patient-level temporal aggregation for text-based asthma status ascertainment. Efficient inverse isoparametric mapping algorithm for whole-body computed tomography registration using deformations predicted by nonlinear finite element modeling. Response of Escherichia coli growth rate to osmotic shock.

A graph algebra for scalable visual analytics. Multiatlas segmentation as nonparametric regression. Coping with confounds in multivoxel pattern analysis: what should we do about reaction time differences? Automatic segmentation of head and neck CT images for radiotherapy treatment planning using multiple atlases, statistical appearance models, and geodesic active contours.

Evaluating marker-guided treatment selection strategies. Variations of dynamic contrast-enhanced magnetic resonance imaging in evaluation of breast cancer therapy response: a multicenter data analysis challenge. Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development. Knowledge-based fragment binding prediction. A complete system for automatic extraction of left ventricular myocardium from CT images using shape segmentation and contour evolution.

Ensuring privacy in the study of pathogen genetics. Mutual information as a measure of image quality for 3D dynamic lung imaging with EIT. Identifying regulatory mechanisms underlying tumorigenesis using locus expression signature analysis. Response to letters regarding article, "unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine".

Population-level evidence for an autoimmune etiology of epilepsy. Joint modeling of imaging and genetics. Geodesic shape regression in the framework of currents. Bayesian segmentation of atrium wall using globally-optimal graph cuts on 3D meshes.

Group-wise cortical correspondence via sulcal curve-constrained entropy minimization. Sparse projections of medical images onto manifolds. A longitudinal functional analysis framework for analysis of white matter tract statistics.

Aldosterone dysregulation with aging predicts renal vascular function and cardiovascular risk. Bayesian energy landscape tilting: towards concordant models of molecular ensembles. Empirical Bayes methods enable advanced population-level analyses of single-molecule FRET experiments. Developing image processing meta-algorithms with data mining of multiple metrics.

Cerebral white matter abnormalities and their associations with negative but not positive symptoms of schizophrenia. Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases.

Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma. High precision prediction of functional sites in protein structures. MAAMD: a workflow to standardize meta-analyses and comparison of affymetrix microarray data.

Neuroinformatics challenges to the structural, connectomic, functional and electrophysiological multimodal imaging of human traumatic brain injury. Changes in tibiofemoral forces due to variations in muscle activity during walking. Pregnancy in women with a history of Kawasaki disease: management and outcomes. Semantics in support of biodiversity knowledge discovery: an introduction to the biological collections ontology and related ontologies.

The automated function prediction SIG looks back at and prepares for Automated detection of off-label drug use.

Multifold Bayesian kernelization in Alzheimer's diagnosis. Geodesic distances to landmarks for dense correspondence on ensembles of complex shapes.

Systematic network lesioning reveals the core white matter scaffold of the human brain. Multi-atlas segmentation of subcortical brain structures via the AutoSeg software pipeline. SAVI: a statistical algorithm for variant frequency identification.

On the mechanics of growing thin biological membranes. Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease. Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes.

When you can't tell when it hurts: a preliminary algorithm to assess pain in patients who can't communicate. Crowdsourcing the verification of relationships in biomedical ontologies. Building and evaluating an ontology-based tool for reasoning about consent permission. Effects of polymerization and nucleotide identity on the conformational dynamics of the bacterial actin homolog MreB. Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness.

Annotating the structure and components of a nanoparticle formulation using computable string expressions. Rare copy number variation in treatment-resistant major depressive disorder. DTIPrep: quality control of diffusion-weighted images. Semi-Automatic Parcellation of the Corpus Striatum. Validation of catheter segmentation for MR-guided gynecologic cancer brachytherapy.

Contour-driven regression for label inference in atlas-based segmentation. Particle-guided image registration. Detecting epileptic regions based on global brain connectivity patterns. Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia.

Specificity of regulatory T cells that modulate vascular inflammation. Differential privacy based on importance weighting. Web-based tools for modelling and analysis of multivariate data: California ozone pollution activity. More accurate neuronavigation data provided by biomechanical modeling instead of rigid registration. MutPred Splice: machine learning-based prediction of exonic variants that disrupt splicing.

Word sense disambiguation in the clinical domain: a comparison of knowledge-rich and knowledge-poor unsupervised methods. Automatic lymphoma classification with sentence subgraph mining from pathology reports. Regional neuroplastic brain changes in patients with chronic inflammatory and non-inflammatory visceral pain. A midas plugin to enable construction of reproducible web-based image processing pipelines. Serum inflammatory markers and risk of colorectal cancer in patients with inflammatory bowel diseases.

A framework for longitudinal data analysis via shape regression. Fast approximate surface evolution in arbitrary dimension. Studying PubMed usages in the field for complex problem solving: Implications for tool design. Atrial fibrillation ablation outcome is predicted by left atrial remodeling on MRI.

Stochastic Image Registration with User Constraints. Fiber feature map based landmark initialization for highly deformable DTI registration. Quality Control of Diffusion Weighted Images. The environment ontology: contextualising biological and biomedical entities. Omnibus risk assessment via accelerated failure time kernel machine modeling. Treatment response in kawasaki disease is associated with sialylation levels of endogenous but not therapeutic intravenous immunoglobulin G.

Comorbidity clusters in autism spectrum disorders: an electronic health record time-series analysis. Mining the ultimate phenome repository. The neurological disease ontology. Discussion of ''Biomedical informatics: we are what we publish''. Amplification and thrifty single-molecule sequencing of recurrent somatic structural variations. Genome-wide DNA methylation changes with age in disease free human skeletal muscle.

Calculations of the electric fields in liquid solutions. Learning signals of adverse drug-drug interactions from the unstructured text of electronic health records. Network analysis of unstructured EHR data for clinical research. Profiling risk factors for chronic uveitis in juvenile idiopathic arthritis: a new model for EHR-based research. Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity.

Associations of smoking and alcohol consumption with disease activity and functional status in rheumatoid arthritis. Predicting the restricted mean event time with the subject's baseline covariates in survival analysis. Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia.

Genetic robustness and functional evolution of gene duplicates. Three-dimensional treatment outcomes in Class II patients treated with the Herbst appliance: a pilot study. Chronology of your health events: approaches to extracting temporal relations from medical narratives. OnTheFly: a database of Drosophila melanogaster transcription factors and their binding sites. SGPP: spatial Gaussian predictive process models for neuroimaging data. State of the human proteome in as viewed through PeptideAtlas: comparing the kidney, urine, and plasma proteomes for the biology- and disease-driven Human Proteome Project.

Reviewing the ketamine model for schizophrenia. Modeling disease severity in multiple sclerosis using electronic health records. Growing matter: a review of growth in living systems. Predictors of plasma and urinary catecholamine levels in normotensive and hypertensive men and women. Towards generating a patient's timeline: extracting temporal relationships from clinical notes. Improved segmentation of white matter tracts with adaptive Riemannian metrics. In silico approaches and the role of ontologies in aging research.

Using search queries for malaria surveillance, Thailand. Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome. Three-dimensional analysis of maxillary changes associated with facemask and rapid maxillary expansion compared with bone anchored maxillary protraction. Neuroimaging of structural pathology and connectomics in traumatic brain injury: Toward personalized outcome prediction. Topology of viral evolution. Regional 3D superimposition to assess temporomandibular joint condylar morphology.

Leveraging electronic health records to notify pediatric patients of a drug recall. Mining clinical text for signals of adverse drug-drug interactions.

Application of universal stress proteins in probing the dynamics of potent degraders in complex terephthalate metagenome. Automated chart review for asthma cohort identification using natural language processing: an exploratory study. Nocturnal continuous glucose and sleep stage data in adults with type 1 diabetes in real-world conditions.

Human neuroimaging as a "Big Data" science. Distinct splice variants and pathway enrichment in the cell-line models of aggressive human breast cancer subtypes. Localized Sparse Code Gradient in Alzheimer's disease staging. Conference proceedings Annual Conference. Nucleotide sequence alignment using sparse coding and belief propagation.

Discovering body site and severity modifiers in clinical texts. Improved de-identification of physician notes through integrative modeling of both public and private medical text. Temporal relation discovery between events and temporal expressions identified in clinical narrative.

FMEM: functional mixed effects modeling for the analysis of longitudinal white matter Tract data. A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk. Neural encoding of acupuncture needling sensations: evidence from a FMRI study. Seasonality of Kawasaki disease: a global perspective. Instrumentation bias in the use and evaluation of scientific software: recommendations for reproducible practices in the computational sciences.

Automatic segmentation of the left atrium from MR images via variational region growing with a moments-based shape prior. Combining an expert-based medical entity recognizer to a machine-learning system: methods and a case study.

Opportunities for genomic clinical decision support interventions. A novel strategy to identify the critical conditions for growth-induced instabilities. Temporomandibular joint condylar changes following maxillomandibular advancement and articular disc repositioning. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. Sex-related differences of cortical thickness in patients with chronic abdominal pain. On the design of clone-based haplotyping.

A molecular signature predictive of indolent prostate cancer. Extraction of events and temporal expressions from clinical narratives. Tissue-specific profiling reveals transcriptome alterations in Arabidopsis mutants lacking morphological phenotypes.

Assessment of biomarkers for risk prediction with nested case-control studies. Electroencephalographic inverse localization of brain activity in acute traumatic brain injury as a guide to surgery, monitoring and treatment. A new tool for sharing and querying of clinical documents modeled using HL7 Version 3 standard. Prostate cancer detection and diagnosis: the role of MR and its comparison with other diagnostic modalities--a radiologist's perspective.

Automated skin segmentation in ultrasonic evaluation of skin toxicity in breast cancer radiotherapy. Using twitter to examine smoking behavior and perceptions of emerging tobacco products. PhenDisco: phenotype discovery system for the database of genotypes and phenotypes. Virmid: accurate detection of somatic mutations with sample impurity inference. Identification of Functional Regulatory Residues of the? Automatic prediction of rheumatoid arthritis disease activity from the electronic medical records.

On the effect of prestrain and residual stress in thin biological membranes. Multimodal deformable registration of traumatic brain injury MR volumes via the Bhattacharyya distance. Toward a comprehensive framework for the spatiotemporal statistical analysis of longitudinal shape data. Identifying phenotypic signatures of neuropsychiatric disorders from electronic medical records.

Classifying temporal relations in clinical data: A hybrid, knowledge-rich approach. Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders. Mapping cortical atrophy in Parkinson's disease patients with dementia. Lipid and lipoprotein levels and trend in rheumatoid arthritis compared to the general population.

Extending the NegEx lexicon for multiple languages. ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer. The integrated landscape of driver genomic alterations in glioblastoma.

Shape abnormalities of the caudate nucleus correlate with poorer gait and balance: results from a subset of the LADIS study. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. Magnetic resonance microscopy-based analyses of the neuroanatomical effects of gestational day 9 ethanol exposure in mice. MedTime: a temporal information extraction system for clinical narratives. Syntactic parsing of clinical text: guideline and corpus development with handling ill-formed sentences.

Immune-monitoring in Kawasaki disease patients treated with infliximab and intravenous immunoglobulin. A locally adaptive regularization based on anisotropic diffusion for deformable image registration of sliding organs. Interactive medical image segmentation using PDE control of active contours. Localizing the human primary auditory cortex in vivo using structural MRI.

Fast local trust region technique for diffusion tensor registration using exact reorientation and regularization. Annotating temporal information in clinical narratives. Semantator: Semantic annotator for converting biomedical text to linked data. From connectivity models to region labels: identifying foci of a neurological disorder. Computational semantics in clinical text. Longitudinal image registration with temporally-dependent image similarity measure.

Variants in exons and in transcription factors affect gene expression in trans. Ground state destabilization by anionic nucleophiles contributes to the activity of phosphoryl transfer enzymes. Statistical shape modeling of cam femoroacetabular impingement.

Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine. Sarcomere lengths in human extensor carpi radialis brevis measured by microendoscopy.

Inference of historical migration rates via haplotype sharing. Improving data and knowledge management to better integrate health care and research. Adopting nested case-control quota sampling designs for the evaluation of risk markers. Decreased axial diffusivity within language connections: A possible biomarker of schizophrenia risk. Sparse texture active contour. Computational modeling of chemo-electro-mechanical coupling: a novel implicit monolithic finite element approach.

Increased gray matter diffusion anisotropy in patients with persistent post-concussive symptoms following mild traumatic brain injury. Privacy technology to support data sharing for comparative effectiveness research: a systematic review. Long-term 3-dimensional stability of mandibular advancement surgery. Using Genome Query Language to uncover genetic variation. Systematic improvement of a classical molecular model of water.

Mechanical consequences of cell-wall turnover in the elongation of a Gram-positive bacterium. Forward and inverse electroencephalographic modeling in health and in acute traumatic brain injury. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology.

Automatic delineation of the myocardial wall from CT images via shape segmentation and variational region growing. Hypothalamic proteoglycan syndecan-3 is a novel cocaine addiction resilience factor.

Evaluating genome architecture of a complex region via generalized bipartite matching. Extracting physician group intelligence from electronic health records to support evidence based medicine.

Dynamic Active Contours for Visual Tracking. Spatial-temporal atlas of human fetal brain development during the early second trimester. Practice-based evidence: profiling the safety of cilostazol by text-mining of clinical notes. Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls.

A rolling constraint reproduces ground reaction forces and moments in dynamic simulations of walking, running, and crouch gait. Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway. Inferences on the biochemical and environmental regulation of universal stress proteins from Schistosomiasis parasites.

Impact of sex and gonadal steroids on neonatal brain structure. Morse-Smale Regression. Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America. A flexible framework for recognizing events, temporal expressions, and temporal relations in clinical text.

Human middle longitudinal fascicle: segregation and behavioral-clinical implications of two distinct fiber connections linking temporal pole and superior temporal gyrus with the angular gyrus or superior parietal lobule using multi-tensor tractography. Diffusion imaging quality control via entropy of principal direction distribution. Temporal reasoning over clinical text: the state of the art. Beyond NPM-anaplastic lymphoma kinase driven lymphomagenesis: alternative drivers in anaplastic large cell lymphoma.

Improving breast cancer survival analysis through competition-based multidimensional modeling. Reprever: resolving low-copy duplicated sequences using template driven assembly. HIV infection reveals widespread expansion of novel centromeric human endogenous retroviruses.

Surgery, virtual reality, and the future. Enhanced modeling via network theory: Adaptive sampling of Markov state models. Her mission: to report on a meeting of thousands of organizers and ambassadors gathered at a global conference on racism. The conference filled Shereen with hope and optimism — all of which would soon be wiped away. This cemetery on the grounds of Carlisle Barracks holds the remains of students from the former Carlisle Indian Industrial School.

Army War College Photo Lab hide caption. Seeing Ghosts , a memoir by Kat Chow. Grand Central Publishing hide caption. In her memoir, Seeing Ghosts , the author and former Code Switch reporter explores how her mother's death has haunted her through the years, in ways that are profound, tragic and, sometimes, darkly hilarious. But they're all students, they're all amazing, and frankly, we're concerned that they might be coming for our jobs.

That's right — the Student Podcast Challenge is back, and this year, the stories are more powerful than ever. So in the spirit of spicing things up, we wanted to give you all a question to fight about: How much context should you have to give when talking about race and culture? Is it better to explain every reference, or ask people to Google as they go?

Comedian Hari Kondabolu joins us to hash it out. But there is so much police violence that falls short of being fatal, but forever alters the lives of the people on the business end of it. Helen Hoang, author of The Kiss Quotient. Eric Kieu hide caption. Today, we're in conversation with a romance novelist whose own identity helped inform a rich cast of characters.

Somebody's Daughter , by Ashley C. In her new memoir, Somebody's Daughter, Ford looks at how her upbringing shaped her understanding of childhood, authority, forgiveness and freedom. Accessibility links Skip to main content Keyboard shortcuts for audio player.

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SELEX-seq: a method for characterizing the complete repertoire of binding site preferences for transcription factor complexes. Complex pathways in folding of protein G explored by simulation and experiment. Evolution of the central sulcus morphology in primates. Treatment selections using risk-benefit profiles based on data from comparative randomized clinical trials with multiple endpoints.

Multiple LacI-mediated loops revealed by Bayesian statistics and tethered particle motion. Classification of CT pulmonary angiography reports by presence, chronicity, and location of pulmonary embolism with natural language processing. Differentially private distributed logistic regression using private and public data. Data-driven discovery of seasonally linked diseases from an Electronic Health Records system.

Multi-atlas segmentation with particle-based group-wise image registration. Impact of family history on prostate cancer mortality in white men undergoing prostate specific antigen based screening. Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records. Lipoprotein particle concentrations in children and adults following Kawasaki disease.

An autism case history to review the systematic analysis of large-scale data to refine the diagnosis and treatment of neuropsychiatric disorders. Robust Radiomics feature quantification using semiautomatic volumetric segmentation. Characterization of living skin using multi-view stereo and isogeometric analysis.

Privacy preserving RBF kernel support vector machine. A mechanical model predicts morphological abnormalities in the developing human brain. Localized abnormalities in the cingulum bundle in patients with schizophrenia: a Diffusion Tensor tractography study.

Prenatal cocaine effects on brain structure in early infancy. Toward personalizing treatment for depression: predicting diagnosis and severity. ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2. Morphometry of anatomical shape complexes with dense deformations and sparse parameters. Characterizing a collective and dynamic component of chromatin immunoprecipitation enrichment profiles in yeast. The elusive evidence for chromothripsis.

Harnessing natural sequence variation to dissect posttranscriptional regulatory networks in yeast. Multi-Channel neurodegenerative pattern analysis and its application in Alzheimer's disease characterization.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. Inferring gene ontologies from pairwise similarity data.

Dysmorphogenic effects of first trimester-equivalent ethanol exposure in mice: a magnetic resonance microscopy-based study. Fluoroquinolone resistant rectal colonization predicts risk of infectious complications after transrectal prostate biopsy.

Integrative biology identifies shared transcriptional networks in CKD. OpenIGTLink interface for state control and visualisation of a robot for image-guided therapy systems. MAGI: a Node. Structural bioinformatics of the interactome. A community effort to assess and improve drug sensitivity prediction algorithms. Natural language processing in biomedicine: a unified system architecture overview. Evaluating the effects of machine pre-annotation and an interactive annotation interface on manual de-identification of clinical text.

Transfer learning based clinical concept extraction on data from multiple sources. Structural and connectomic neuroimaging for the personalized study of longitudinal alterations in cortical shape, thickness and connectivity after traumatic brain injury. Meshless Modeling of Deformable Shapes and their Motion. Patient-level temporal aggregation for text-based asthma status ascertainment.

Efficient inverse isoparametric mapping algorithm for whole-body computed tomography registration using deformations predicted by nonlinear finite element modeling.

Response of Escherichia coli growth rate to osmotic shock. A graph algebra for scalable visual analytics. Multiatlas segmentation as nonparametric regression. Coping with confounds in multivoxel pattern analysis: what should we do about reaction time differences? Automatic segmentation of head and neck CT images for radiotherapy treatment planning using multiple atlases, statistical appearance models, and geodesic active contours.

Evaluating marker-guided treatment selection strategies. Variations of dynamic contrast-enhanced magnetic resonance imaging in evaluation of breast cancer therapy response: a multicenter data analysis challenge. Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development.

Knowledge-based fragment binding prediction. A complete system for automatic extraction of left ventricular myocardium from CT images using shape segmentation and contour evolution.

Ensuring privacy in the study of pathogen genetics. Mutual information as a measure of image quality for 3D dynamic lung imaging with EIT. Identifying regulatory mechanisms underlying tumorigenesis using locus expression signature analysis. Response to letters regarding article, "unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine". Population-level evidence for an autoimmune etiology of epilepsy. Joint modeling of imaging and genetics.

Geodesic shape regression in the framework of currents. Bayesian segmentation of atrium wall using globally-optimal graph cuts on 3D meshes. Group-wise cortical correspondence via sulcal curve-constrained entropy minimization.

Sparse projections of medical images onto manifolds. A longitudinal functional analysis framework for analysis of white matter tract statistics. Aldosterone dysregulation with aging predicts renal vascular function and cardiovascular risk.

Bayesian energy landscape tilting: towards concordant models of molecular ensembles. Empirical Bayes methods enable advanced population-level analyses of single-molecule FRET experiments.

Developing image processing meta-algorithms with data mining of multiple metrics. Cerebral white matter abnormalities and their associations with negative but not positive symptoms of schizophrenia.

Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases. Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma. High precision prediction of functional sites in protein structures. MAAMD: a workflow to standardize meta-analyses and comparison of affymetrix microarray data.

Neuroinformatics challenges to the structural, connectomic, functional and electrophysiological multimodal imaging of human traumatic brain injury. Changes in tibiofemoral forces due to variations in muscle activity during walking. Pregnancy in women with a history of Kawasaki disease: management and outcomes. Semantics in support of biodiversity knowledge discovery: an introduction to the biological collections ontology and related ontologies. The automated function prediction SIG looks back at and prepares for Automated detection of off-label drug use.

Multifold Bayesian kernelization in Alzheimer's diagnosis. Geodesic distances to landmarks for dense correspondence on ensembles of complex shapes. Systematic network lesioning reveals the core white matter scaffold of the human brain. Multi-atlas segmentation of subcortical brain structures via the AutoSeg software pipeline.

SAVI: a statistical algorithm for variant frequency identification. On the mechanics of growing thin biological membranes. Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease. Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes. When you can't tell when it hurts: a preliminary algorithm to assess pain in patients who can't communicate.

Crowdsourcing the verification of relationships in biomedical ontologies. Building and evaluating an ontology-based tool for reasoning about consent permission. Effects of polymerization and nucleotide identity on the conformational dynamics of the bacterial actin homolog MreB. Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness. Annotating the structure and components of a nanoparticle formulation using computable string expressions.

Rare copy number variation in treatment-resistant major depressive disorder. DTIPrep: quality control of diffusion-weighted images. Semi-Automatic Parcellation of the Corpus Striatum.

Validation of catheter segmentation for MR-guided gynecologic cancer brachytherapy. Contour-driven regression for label inference in atlas-based segmentation. Particle-guided image registration. Detecting epileptic regions based on global brain connectivity patterns.

Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia. Specificity of regulatory T cells that modulate vascular inflammation. Differential privacy based on importance weighting. Web-based tools for modelling and analysis of multivariate data: California ozone pollution activity. More accurate neuronavigation data provided by biomechanical modeling instead of rigid registration.

MutPred Splice: machine learning-based prediction of exonic variants that disrupt splicing. Word sense disambiguation in the clinical domain: a comparison of knowledge-rich and knowledge-poor unsupervised methods. Automatic lymphoma classification with sentence subgraph mining from pathology reports.

Regional neuroplastic brain changes in patients with chronic inflammatory and non-inflammatory visceral pain. A midas plugin to enable construction of reproducible web-based image processing pipelines.

Serum inflammatory markers and risk of colorectal cancer in patients with inflammatory bowel diseases. A framework for longitudinal data analysis via shape regression. Fast approximate surface evolution in arbitrary dimension.

Studying PubMed usages in the field for complex problem solving: Implications for tool design. Atrial fibrillation ablation outcome is predicted by left atrial remodeling on MRI.

Stochastic Image Registration with User Constraints. Fiber feature map based landmark initialization for highly deformable DTI registration. Quality Control of Diffusion Weighted Images. The environment ontology: contextualising biological and biomedical entities.

Omnibus risk assessment via accelerated failure time kernel machine modeling. Treatment response in kawasaki disease is associated with sialylation levels of endogenous but not therapeutic intravenous immunoglobulin G. Comorbidity clusters in autism spectrum disorders: an electronic health record time-series analysis. Mining the ultimate phenome repository. The neurological disease ontology. Discussion of ''Biomedical informatics: we are what we publish''.

Amplification and thrifty single-molecule sequencing of recurrent somatic structural variations. Genome-wide DNA methylation changes with age in disease free human skeletal muscle. Calculations of the electric fields in liquid solutions. Learning signals of adverse drug-drug interactions from the unstructured text of electronic health records.

Network analysis of unstructured EHR data for clinical research. Profiling risk factors for chronic uveitis in juvenile idiopathic arthritis: a new model for EHR-based research. Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. Associations of smoking and alcohol consumption with disease activity and functional status in rheumatoid arthritis. Predicting the restricted mean event time with the subject's baseline covariates in survival analysis.

Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia. Genetic robustness and functional evolution of gene duplicates. Three-dimensional treatment outcomes in Class II patients treated with the Herbst appliance: a pilot study.

Chronology of your health events: approaches to extracting temporal relations from medical narratives. OnTheFly: a database of Drosophila melanogaster transcription factors and their binding sites.

SGPP: spatial Gaussian predictive process models for neuroimaging data. State of the human proteome in as viewed through PeptideAtlas: comparing the kidney, urine, and plasma proteomes for the biology- and disease-driven Human Proteome Project. Reviewing the ketamine model for schizophrenia. Modeling disease severity in multiple sclerosis using electronic health records. Growing matter: a review of growth in living systems. Predictors of plasma and urinary catecholamine levels in normotensive and hypertensive men and women.

Towards generating a patient's timeline: extracting temporal relationships from clinical notes. Improved segmentation of white matter tracts with adaptive Riemannian metrics. In silico approaches and the role of ontologies in aging research. Using search queries for malaria surveillance, Thailand. Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome.

Three-dimensional analysis of maxillary changes associated with facemask and rapid maxillary expansion compared with bone anchored maxillary protraction. Neuroimaging of structural pathology and connectomics in traumatic brain injury: Toward personalized outcome prediction. Topology of viral evolution.

Regional 3D superimposition to assess temporomandibular joint condylar morphology. Leveraging electronic health records to notify pediatric patients of a drug recall.

Mining clinical text for signals of adverse drug-drug interactions. Application of universal stress proteins in probing the dynamics of potent degraders in complex terephthalate metagenome. Automated chart review for asthma cohort identification using natural language processing: an exploratory study. Nocturnal continuous glucose and sleep stage data in adults with type 1 diabetes in real-world conditions. Human neuroimaging as a "Big Data" science. Distinct splice variants and pathway enrichment in the cell-line models of aggressive human breast cancer subtypes.

Localized Sparse Code Gradient in Alzheimer's disease staging. Conference proceedings Annual Conference. Nucleotide sequence alignment using sparse coding and belief propagation. Discovering body site and severity modifiers in clinical texts.

Improved de-identification of physician notes through integrative modeling of both public and private medical text. Temporal relation discovery between events and temporal expressions identified in clinical narrative.

FMEM: functional mixed effects modeling for the analysis of longitudinal white matter Tract data. A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk. Neural encoding of acupuncture needling sensations: evidence from a FMRI study.

Seasonality of Kawasaki disease: a global perspective. Instrumentation bias in the use and evaluation of scientific software: recommendations for reproducible practices in the computational sciences. Automatic segmentation of the left atrium from MR images via variational region growing with a moments-based shape prior. Combining an expert-based medical entity recognizer to a machine-learning system: methods and a case study. Opportunities for genomic clinical decision support interventions.

A novel strategy to identify the critical conditions for growth-induced instabilities. Temporomandibular joint condylar changes following maxillomandibular advancement and articular disc repositioning. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

Sex-related differences of cortical thickness in patients with chronic abdominal pain. On the design of clone-based haplotyping. A molecular signature predictive of indolent prostate cancer. Extraction of events and temporal expressions from clinical narratives.

Tissue-specific profiling reveals transcriptome alterations in Arabidopsis mutants lacking morphological phenotypes. Assessment of biomarkers for risk prediction with nested case-control studies. Electroencephalographic inverse localization of brain activity in acute traumatic brain injury as a guide to surgery, monitoring and treatment. A new tool for sharing and querying of clinical documents modeled using HL7 Version 3 standard. Prostate cancer detection and diagnosis: the role of MR and its comparison with other diagnostic modalities--a radiologist's perspective.

Automated skin segmentation in ultrasonic evaluation of skin toxicity in breast cancer radiotherapy. Using twitter to examine smoking behavior and perceptions of emerging tobacco products. PhenDisco: phenotype discovery system for the database of genotypes and phenotypes.

Virmid: accurate detection of somatic mutations with sample impurity inference. Identification of Functional Regulatory Residues of the? Automatic prediction of rheumatoid arthritis disease activity from the electronic medical records.

On the effect of prestrain and residual stress in thin biological membranes. Multimodal deformable registration of traumatic brain injury MR volumes via the Bhattacharyya distance. Toward a comprehensive framework for the spatiotemporal statistical analysis of longitudinal shape data.

Identifying phenotypic signatures of neuropsychiatric disorders from electronic medical records. Classifying temporal relations in clinical data: A hybrid, knowledge-rich approach.

Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders. Mapping cortical atrophy in Parkinson's disease patients with dementia. Lipid and lipoprotein levels and trend in rheumatoid arthritis compared to the general population. Extending the NegEx lexicon for multiple languages. ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer.

The integrated landscape of driver genomic alterations in glioblastoma. Shape abnormalities of the caudate nucleus correlate with poorer gait and balance: results from a subset of the LADIS study. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. Magnetic resonance microscopy-based analyses of the neuroanatomical effects of gestational day 9 ethanol exposure in mice.

MedTime: a temporal information extraction system for clinical narratives. Syntactic parsing of clinical text: guideline and corpus development with handling ill-formed sentences. Immune-monitoring in Kawasaki disease patients treated with infliximab and intravenous immunoglobulin.

A locally adaptive regularization based on anisotropic diffusion for deformable image registration of sliding organs. Interactive medical image segmentation using PDE control of active contours. Localizing the human primary auditory cortex in vivo using structural MRI. Fast local trust region technique for diffusion tensor registration using exact reorientation and regularization. Annotating temporal information in clinical narratives.

Semantator: Semantic annotator for converting biomedical text to linked data. From connectivity models to region labels: identifying foci of a neurological disorder. Computational semantics in clinical text. Longitudinal image registration with temporally-dependent image similarity measure.

Variants in exons and in transcription factors affect gene expression in trans. Ground state destabilization by anionic nucleophiles contributes to the activity of phosphoryl transfer enzymes. Statistical shape modeling of cam femoroacetabular impingement.

Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine. Sarcomere lengths in human extensor carpi radialis brevis measured by microendoscopy. Inference of historical migration rates via haplotype sharing. Improving data and knowledge management to better integrate health care and research. Adopting nested case-control quota sampling designs for the evaluation of risk markers.

Decreased axial diffusivity within language connections: A possible biomarker of schizophrenia risk. Sparse texture active contour. Computational modeling of chemo-electro-mechanical coupling: a novel implicit monolithic finite element approach. Increased gray matter diffusion anisotropy in patients with persistent post-concussive symptoms following mild traumatic brain injury.

Privacy technology to support data sharing for comparative effectiveness research: a systematic review. Long-term 3-dimensional stability of mandibular advancement surgery. Using Genome Query Language to uncover genetic variation. Systematic improvement of a classical molecular model of water. Mechanical consequences of cell-wall turnover in the elongation of a Gram-positive bacterium. Forward and inverse electroencephalographic modeling in health and in acute traumatic brain injury.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. Automatic delineation of the myocardial wall from CT images via shape segmentation and variational region growing.

Hypothalamic proteoglycan syndecan-3 is a novel cocaine addiction resilience factor. Evaluating genome architecture of a complex region via generalized bipartite matching. Extracting physician group intelligence from electronic health records to support evidence based medicine. Dynamic Active Contours for Visual Tracking.

Spatial-temporal atlas of human fetal brain development during the early second trimester. Practice-based evidence: profiling the safety of cilostazol by text-mining of clinical notes. Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls.

A rolling constraint reproduces ground reaction forces and moments in dynamic simulations of walking, running, and crouch gait. Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway. Inferences on the biochemical and environmental regulation of universal stress proteins from Schistosomiasis parasites. Impact of sex and gonadal steroids on neonatal brain structure. Morse-Smale Regression.

Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America. A flexible framework for recognizing events, temporal expressions, and temporal relations in clinical text. Human middle longitudinal fascicle: segregation and behavioral-clinical implications of two distinct fiber connections linking temporal pole and superior temporal gyrus with the angular gyrus or superior parietal lobule using multi-tensor tractography.

Diffusion imaging quality control via entropy of principal direction distribution. Temporal reasoning over clinical text: the state of the art. Beyond NPM-anaplastic lymphoma kinase driven lymphomagenesis: alternative drivers in anaplastic large cell lymphoma. Improving breast cancer survival analysis through competition-based multidimensional modeling. Reprever: resolving low-copy duplicated sequences using template driven assembly. HIV infection reveals widespread expansion of novel centromeric human endogenous retroviruses.

Surgery, virtual reality, and the future. Enhanced modeling via network theory: Adaptive sampling of Markov state models. Growth on demand: Reviewing the mechanobiology of stretched skin.

Optical flow estimation for flame detection in videos. Genetic contributions to changes of fiber tracts of ventral visual stream in 22q Lateral ventricle morphology analysis via mean latitude axis. On the mechanics of continua with boundary energies and growing surfaces. Combining rules and machine learning for extraction of temporal expressions and events from clinical narratives. Heterogeneity of tumor-induced gene expression changes in the human metabolic network.

Innovations in proteomic profiling of cancers: alternative splice variants as a new class of cancer biomarker candidates and bridging of proteomics with structural biology. Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer.

Dominant effects of the Huntington's disease HTT CAG repeat length are captured in gene-expression data sets by a continuous analysis mathematical modeling strategy. Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver.

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Towards improved ultrasound-based analysis and 3D visualization of the fetal brain using the 3D Slicer. Eventual situations for timeline extraction from clinical reports.

A hybrid system for temporal information extraction from clinical text. Pharmacovigilance using clinical notes. Performance of pharmacovigilance signal-detection algorithms for the FDA adverse event reporting system. Diffusion weighted imaging of prefrontal cortex in prodromal huntington's disease. Evaluating temporal relations in clinical text: i2b2 Challenge. A controlled greedy supervised approach for co-reference resolution on clinical text.

Comprehensive temporal information detection from clinical text: medical events, time, and TLINK identification. Natural Language Processing to identify pneumonia from radiology reports. The stationary configuration of the knee. MutComFocal: an integrative approach to identifying recurrent and focal genomic alterations in tumor samples.

An informational framework to predict reaction of constraints using a reciprocally connected knee model. An algorithmic approach for breakage-fusion-bridge detection in tumor genomes.

Six-week gait retraining program reduces knee adduction moment, reduces pain, and improves function for individuals with medial compartment knee osteoarthritis.

Landmark risk prediction of residual life for breast cancer survival. Differential expression of miR in children with Kawasaki disease. How muscle fiber lengths and velocities affect muscle force generation as humans walk and run at different speeds. An end-to-end system to identify temporal relation in discharge summaries: i2b2 challenge. Web-scale pharmacovigilance: listening to signals from the crowd.

Automating the study of population variation of electrocardiographic features. Referent tracking for treatment optimisation in schizophrenic patients: A case study in applying philosophical ontology to diagnostic algorithms. Stretching skin: The physiological limit and beyond. GBM volumetry using the 3D Slicer medical image computing platform.

Flexing computational muscle: modeling and simulation of musculotendon dynamics. Comparison of four prediction models to discriminate benign from malignant vertebral compression fractures according to MRI feature analysis.

From single nucleotide polymorphism to transcriptional mechanism: a model for FRMD3 in diabetic nephropathy. MetaSeq: privacy preserving meta-analysis of sequencing-based association studies. Insights into diseases of human telomerase from dynamical modeling. Molecular dynamics simulations for the ranking, evaluation, and refinement of computationally designed proteins. Wessim: a whole-exome sequencing simulator based on in silico exome capture.

N-glycoproteome of E Tg2a mouse embryonic stem cells. One-year assessment of surgical outcomes in Class III patients using cone beam computed tomography. Abnormal aldosterone physiology and cardiometabolic risk factors. Classic "broken cell" techniques and newer live cell methods for cell cycle assessment.

Properties of cell death models calibrated and compared using Bayesian approaches. Detecting concept relations in clinical text: insights from a state-of-the-art model. Recursive feature elimination for brain tumor classification using desorption electrospray ionization mass spectrometry imaging.

Automatic segmentation of the left atrium from MRI images using salient feature and contour evolution. Quantifying pathogen surveillance using temporal genomic data. QT interval and antidepressant use: a cross sectional study of electronic health records. Gene expression alterations in bipolar disorder postmortem brains. Multiscale adaptive generalized estimating equations for longitudinal neuroimaging data.

Evaluation of methods for modeling transcription factor sequence specificity. A large-scale evaluation of computational protein function prediction. Federated queries of clinical data repositories: the sum of the parts does not equal the whole. White matter fractional anisotropy is inversely related to anxious symptoms in older adults with atherosclerosis. Similar risk of depression and anxiety following surgery or hospitalization for Crohn's disease and ulcerative colitis. Exact statistical tests for the intersection of independent lists of genes.

Systems-based approaches toward wound healing. Sexually dimorphic white matter geometry abnormalities in adolescent onset schizophrenia. Selecting cases for whom additional tests can improve prognostication. Towards mechanism classifiers: expression-anchored Gene Ontology signature predicts clinical outcome in lung adenocarcinoma patients. Towards the creation of a visual ontology of biomedical imaging entities.

The relationship between structural characteristics of challenge documents and ratings of document quality. Applications of ontology design patterns in biomedical ontologies.

A semi-automated quantification of pulmonary artery dimensions in computed tomography angiography images. Chapter 9: Analyses using disease ontologies. Abnormalities of middle longitudinal fascicle and disorganization in patients with schizophrenia.

Psychiatric co-morbidity is associated with increased risk of surgery in Crohn's disease. Learning a reliable estimate of the number of fiber directions in diffusion MRI. Spectral label fusion. Longitudinal image registration with non-uniform appearance change. Topology preserving atlas construction from shape data without correspondence using sparse parameters. Metamorphic geodesic regression. Group analysis of resting-state fMRI by hierarchical Markov random fields.

A feature-based developmental model of the infant brain in structural MRI. Fast diffusion tensor registration with exact reorientation and regularization. Analytic regularization of uniform cubic B-spline deformation fields. Analysis of longitudinal shape variability via subject specific growth modeling. From brain connectivity models to identifying foci of a neurological disorder.

Common variants in psychiatric risk genes predict brain structure at birth. MicroRNA-centric measurement improves functional enrichment analysis of co-expressed and differentially expressed microRNA clusters. Regionally selective atrophy of subcortical structures in prodromal HD as revealed by statistical shape analysis.

OntoMaton: a bioportal powered ontology widget for Google Spreadsheets. The variance of identity-by-descent sharing in the Wright-Fisher model. Subgroup specific incremental value of new markers for risk prediction. Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis.

A chromosome-centric human proteome project C-HPP to characterize the sets of proteins encoded in chromosome Tissue plasminogen activator prevents mortality from sulfur mustard analog-induced airway obstruction. Fiber tractography based on diffusion tensor imaging compared with high-angular-resolution diffusion imaging with compressed sensing: initial experience.

Evaluating incremental values from new predictors with net reclassification improvement in survival analysis. To share or not to share: that is not the question.

Muscle contributions to fore-aft and vertical body mass center accelerations over a range of running speeds. Sharing data for the public good and protecting individual privacy: informatics solutions to combine different goals. Privacy-preserving heterogeneous health data sharing. Pituitary adenoma volumetry with 3D Slicer. To milliseconds and beyond: challenges in the simulation of protein folding. Regional characterization of longitudinal DT-MRI to study white matter maturation of the early developing brain.

Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls. The plant ontology as a tool for comparative plant anatomy and genomic analyses.

Generating fibre orientation maps in human heart models using Poisson interpolation. Ontology-based combinatorial comparative analysis of adverse events associated with killed and live influenza vaccines. Muscle contributions to vertical and fore-aft accelerations are altered in subjects with crouch gait. ArrayExpress update--trends in database growth and links to data analysis tools. PrePPI: a structure-informed database of protein-protein interactions.

Toward an understanding of the short bone phenotype associated with multiple osteochondromas. The Measurement of Local Variation in Shape. A fully implicit finite element method for bidomain models of cardiac electromechanics. Evaluating the predictive value of biomarkers with stratified case-cohort design. Patellar maltracking is prevalent among patellofemoral pain subjects with patella alta: an upright, weightbearing MRI study.

Collaborative software for traditional and translational research. Feasibility of studying brain morphology in major depressive disorder with structural magnetic resonance imaging and clinical data from the electronic medical record: a pilot study. Toe-in gait reduces the first peak knee adduction moment in patients with medial compartment knee osteoarthritis.

Differences in subcortical structures in young adolescents at familial risk for schizophrenia: a preliminary study. Longitudinal analysis of pain in patients with metastatic prostate cancer using natural language processing of medical record text. Diverse types of genetic variation converge on functional gene networks involved in schizophrenia.

Localized differences in caudate and hippocampal shape are associated with schizophrenia but not antipsychotic type. The influence of sodium- and calcium-regulatory hormone interventions on adipocytokines in obesity and diabetes.

Broadening instructional scope with network visualization. Mathematical modeling of collagen turnover in biological tissue. Image registration using radial basis functions with adaptive radius. Combing signals from spontaneous reports and electronic health records for detection of adverse drug reactions. The structural, connectomic and network covariance of the human brain.

Knowledge building insights on biomarkers of arsenic toxicity to keratinocytes and melanocytes. Computational modelling of electrocardiograms: repolarisation and T-wave polarity in the human heart.

Length distributions of identity by descent reveal fine-scale demographic history. Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes.

Tor1 regulates protein solubility in Saccharomyces cerevisiae. The structure of the corpus callosum in obsessive compulsive disorder. On removing interpolation and resampling artifacts in rigid image registration.

Multicenter reliability of diffusion tensor imaging. Detecting identity by descent and homozygosity mapping in whole-exome sequencing data.

Automated dispersion and orientation analysis for carbon nanotube reinforced polymer composites. A rule based solution to co-reference resolution in clinical text. SHARE: system design and case studies for statistical health information release. Stretching skeletal muscle: chronic muscle lengthening through sarcomerogenesis. An excess of deleterious variants in VEGF-A pathway genes in Down-syndrome-associated atrioventricular septal defects. A unified inference procedure for a class of measures to assess improvement in risk prediction systems with survival data.

Comparative profiling of miRNA expression of lung adenocarcinoma cells in two-dimensional and three-dimensional cultures. LRpath analysis reveals common pathways dysregulated via DNA methylation across cancer types. Antidepressant response in patients with major depression exposed to NSAIDs: a pharmacovigilance study.

Adaptive prior probability and spatial temporal intensity change estimation for segmentation of the one-year-old human brain. Changes in in vivo knee contact forces through gait modification.

Terminology representation guidelines for biomedical ontologies in the semantic web notations. Structure-based prediction of protein-protein interactions on a genome-wide scale. Anisotropic conductivity of magnetic carbon nanotubes embedded in epoxy matrices. Neuropsychological variability, symptoms, and brain imaging in chronic schizophrenia.

Imaging nigral pathology and clinical progression in Parkinson's disease. Setting up an intronic miRNA database. Extended Broca's area in the functional connectome of language in adults: combined cortical and subcortical single-subject analysis using fMRI and DTI tractography.

Comprehensive molecular portraits of human breast tumours. Associations between white matter microstructure and infants' working memory.

Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter. Global probabilistic annotation of metabolic networks enables enzyme discovery. How much muscle strength is required to walk in a crouch gait? In-bore setup and software for 3T MRI-guided transperineal prostate biopsy. Calibration of multiple in silico tools for predicting pathogenicity of mismatch repair gene missense substitutions. Nanoinformatics: developing new computing applications for nanomedicine.

Designing a public square for research computing. Frontiers in growth and remodeling. Utilizing the integrated difference of two survival functions to quantify the treatment contrast for designing, monitoring, and analyzing a comparative clinical study.

A gene expression profile of stem cell pluripotentiality and differentiation is conserved across diverse solid and hematopoietic cancers. Translational bioinformatics embraces big data. Contributions of muscles to mediolateral ground reaction force over a range of walking speeds. North African Jewish and non-Jewish populations form distinctive, orthogonal clusters. Pharmacokinetics and pharmacodynamics of oral artesunate monotherapy in patients with uncomplicated Plasmodium falciparum malaria in western Cambodia.

Nonmodulation as the mechanism for salt sensitivity of blood pressure in individuals with hypertension and type 2 diabetes mellitus. Reduced fractional anisotropy and axial diffusivity in white matter in 22q Large-scale evaluation of automated clinical note de-identification and its impact on information extraction.

Emergence of fatal avian influenza in New England harbor seals. Ontologies as integrative tools for plant science. A role for ephrin-A5 in axonal sprouting, recovery, and activity-dependent plasticity after stroke. Leveraging models of cell regulation and GWAS data in integrative network-based association studies.

Mining the pharmacogenomics literature--a survey of the state of the art. A 3D interactive multi-object segmentation tool using local robust statistics driven active contours. How many neutrophils are enough redux, redux? Comparative protein interactomics of neuroglobin and myoglobin.

Wisdom of crowds for robust gene network inference. Human middle longitudinal fascicle: variations in patterns of anatomical connections. Using domain knowledge and domain-inspired discourse model for coreference resolution for clinical narratives. Context-specific ontology integration: a bayesian approach. Analyzing patterns of drug use in clinical notes for patient safety.

Using temporal patterns in medical records to discern adverse drug events from indications. Formal concept analysis of disease similarity. Semantator: annotating clinical narratives with semantic web ontologies. Analysis of high-throughput screening assays using cluster enrichment. Reviewing social media use by clinicians. Filtering in the diffeomorphism group and the registration of point sets. Genetic correction of Huntington's disease phenotypes in induced pluripotent stem cells.

Identifying genetic marker sets associated with phenotypes via an efficient adaptive score test. Semiparametric Bayesian local functional models for diffusion tensor tract statistics. The coming age of data-driven medicine: translational bioinformatics' next frontier. Endoscopic image analysis in semantic space. Genetics insights into the pathogenesis of Kawasaki disease. Coreference analysis in clinical notes: a multi-pass sieve with alternate anaphora resolution modules.

Active learning for clinical text classification: is it better than random sampling? DEFOG: discrete enrichment of functionally organized genes. Bioinformatics advances in saliva diagnostics. Characteristics associated with improved knee extension after strength training for individuals with cerebral palsy and crouch gait.

A survey of informatics platforms that enable distributed comparative effectiveness research using multi-institutional heterogenous clinical data.

Brain volume findings in 6-month-old infants at high familial risk for autism. Polymorphisms in the serum- and glucocorticoid-inducible kinase 1 gene are associated with blood pressure and renin response to dietary salt intake. Structural brain atlases: design, rationale, and applications in normal and pathological cohorts. Image registration for targeted MRI-guided transperineal prostate biopsy.

Obstetric complications and risk for conversion to psychosis among individuals at high clinical risk. Template-cut: a pattern-based segmentation paradigm. Towards automatic diabetes case detection and ABCS protocol compliance assessment. Whole brain resting state functional connectivity abnormalities in schizophrenia.

Mapping connectivity damage in the case of Phineas Gage. A supervised framework for resolving coreference in clinical records. Machine learning-based coreference resolution of concepts in clinical documents. Central nervous system endoplasmic reticulum stress in a murine model of type 2 diabetes. Predicting the metabolic cost of incline walking from muscle activity and walking mechanics.

The microRNA expression associated with morphogenesis of breast cancer cells in three-dimensional organotypic culture. Recognition of medication information from discharge summaries using ensembles of classifiers. Coreference resolution of medical concepts in discharge summaries by exploiting contextual information. Bioinformatics and variability in drug response: a protein structural perspective.

Novel data-mining methodologies for adverse drug event discovery and analysis. Evolutionary molecular medicine. Crouched posture maximizes ground reaction forces generated by muscles. Limbic system white matter microstructure and long-term treatment outcome in major depressive disorder: a diffusion tensor imaging study using legacy data.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. Vitamin D3 therapy corrects the tissue sensitivity to angiotensin ii akin to the action of a converting enzyme inhibitor in obese hypertensives: an interventional study. Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus. Lysine-specific demethylase 1: an epigenetic regulator of salt-sensitive hypertension.

Functional organization and its implication in evolution of the human protein-protein interaction network. An image analysis toolbox for high-throughput C. Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4.

The co-morbidity burden of children and young adults with autism spectrum disorders. Protecting count queries in study design. Quantitative tract-based white matter development from birth to age 2years.

A classification approach to coreference in discharge summaries: i2b2 challenge. Structure-based drug screening for G-protein-coupled receptors. Using ontology-based annotation to profile disease research. Afghanistan has a long, rich, complex history and culture.

A lot of it flies in the face of the images those of us in the U. So this week, our friends at Throughline are helping us understand the fuller story. The cover of Bethany C. Morrow's new book, So Many Beginnings.

Jonathan Barkat hide caption. Trump supporters try to break through a police barrier Jan. Capitol in Washington, D. It's a powerful term that's had lasting implications for communities around the world. Alexis Nikole Nelson is behind the popular TikTok and Instagram videos based on her experience and advice on foraging. Her mission: to report on a meeting of thousands of organizers and ambassadors gathered at a global conference on racism. The conference filled Shereen with hope and optimism — all of which would soon be wiped away.

This cemetery on the grounds of Carlisle Barracks holds the remains of students from the former Carlisle Indian Industrial School. Army War College Photo Lab hide caption. Seeing Ghosts , a memoir by Kat Chow. Grand Central Publishing hide caption. In her memoir, Seeing Ghosts , the author and former Code Switch reporter explores how her mother's death has haunted her through the years, in ways that are profound, tragic and, sometimes, darkly hilarious. But they're all students, they're all amazing, and frankly, we're concerned that they might be coming for our jobs.

That's right — the Student Podcast Challenge is back, and this year, the stories are more powerful than ever. So in the spirit of spicing things up, we wanted to give you all a question to fight about: How much context should you have to give when talking about race and culture?

Is it better to explain every reference, or ask people to Google as they go? Comedian Hari Kondabolu joins us to hash it out. But there is so much police violence that falls short of being fatal, but forever alters the lives of the people on the business end of it.

Helen Hoang, author of The Kiss Quotient. Eric Kieu hide caption.

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Android TV Box. Yesterday at AM TonyStark. InfoTech Clinics www. Popular topics include computer set-up, configuration, tweaking, processors, motherboards, graphics cards, monitors, SSD, hard drives, NAS, speakers, printers, input devices and more! Threads Is Cat 5e Lan cable still relevant? A moment ago Clearnfc. Discussions include hardware and technical-related issues. Threads 5. Laptop Advice for Work. Today at AM yusoffb ISP plans, decisions and feedback?

Optimizing connection speed? Wired and Wireless Networking queries? If it's about broadband, internet bandwidth and networking, it's HERE. Threads 9. Today at AM linwenquan Welcome to Apple Haven. Threads 8. Today at AM xiaosen. Threads 3. Import songs from remote CD drive into iTunes. Gaming Arena The one forum for all gaming discussions! Whether you're a PlayStation, Xbox, Nintendo console fan or a PC, handheld, smartphone gamer, level up your game, share your tips and tricks, discuss which game port is superior or hire new teammates for your gaming session - this forum is THE home for all things gaming.

Game on! In collaboration with. Today at AM SmartVanquisher. Yesterday at PM eltonhjohn1. Discuss all about AV Recievers, amplifiers, speakers, blu-ray players, media players and more! Today at AM SyncGuy. Headphones, Earphones and Portable Media Devices These personal listening equipment are very important with the ever-growing variety of portable media consumption devices like phones, tablets, PMPs, etc. Threads 4. Soundcore Liberty 3 pro TWS earbuds. Automatic segmentation of the left atrium from MRI images using salient feature and contour evolution.

Quantifying pathogen surveillance using temporal genomic data. QT interval and antidepressant use: a cross sectional study of electronic health records. Gene expression alterations in bipolar disorder postmortem brains.

Multiscale adaptive generalized estimating equations for longitudinal neuroimaging data. Evaluation of methods for modeling transcription factor sequence specificity. A large-scale evaluation of computational protein function prediction. Federated queries of clinical data repositories: the sum of the parts does not equal the whole.

White matter fractional anisotropy is inversely related to anxious symptoms in older adults with atherosclerosis. Similar risk of depression and anxiety following surgery or hospitalization for Crohn's disease and ulcerative colitis.

Exact statistical tests for the intersection of independent lists of genes. Systems-based approaches toward wound healing. Sexually dimorphic white matter geometry abnormalities in adolescent onset schizophrenia. Selecting cases for whom additional tests can improve prognostication. Towards mechanism classifiers: expression-anchored Gene Ontology signature predicts clinical outcome in lung adenocarcinoma patients.

Towards the creation of a visual ontology of biomedical imaging entities. The relationship between structural characteristics of challenge documents and ratings of document quality. Applications of ontology design patterns in biomedical ontologies. A semi-automated quantification of pulmonary artery dimensions in computed tomography angiography images.

Chapter 9: Analyses using disease ontologies. Abnormalities of middle longitudinal fascicle and disorganization in patients with schizophrenia. Psychiatric co-morbidity is associated with increased risk of surgery in Crohn's disease.

Learning a reliable estimate of the number of fiber directions in diffusion MRI. Spectral label fusion. Longitudinal image registration with non-uniform appearance change. Topology preserving atlas construction from shape data without correspondence using sparse parameters. Metamorphic geodesic regression.

Group analysis of resting-state fMRI by hierarchical Markov random fields. A feature-based developmental model of the infant brain in structural MRI. Fast diffusion tensor registration with exact reorientation and regularization. Analytic regularization of uniform cubic B-spline deformation fields. Analysis of longitudinal shape variability via subject specific growth modeling. From brain connectivity models to identifying foci of a neurological disorder. Common variants in psychiatric risk genes predict brain structure at birth.

MicroRNA-centric measurement improves functional enrichment analysis of co-expressed and differentially expressed microRNA clusters. Regionally selective atrophy of subcortical structures in prodromal HD as revealed by statistical shape analysis. OntoMaton: a bioportal powered ontology widget for Google Spreadsheets.

The variance of identity-by-descent sharing in the Wright-Fisher model. Subgroup specific incremental value of new markers for risk prediction. Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis.

A chromosome-centric human proteome project C-HPP to characterize the sets of proteins encoded in chromosome Tissue plasminogen activator prevents mortality from sulfur mustard analog-induced airway obstruction. Fiber tractography based on diffusion tensor imaging compared with high-angular-resolution diffusion imaging with compressed sensing: initial experience.

Evaluating incremental values from new predictors with net reclassification improvement in survival analysis. To share or not to share: that is not the question. Muscle contributions to fore-aft and vertical body mass center accelerations over a range of running speeds. Sharing data for the public good and protecting individual privacy: informatics solutions to combine different goals. Privacy-preserving heterogeneous health data sharing.

Pituitary adenoma volumetry with 3D Slicer. To milliseconds and beyond: challenges in the simulation of protein folding. Regional characterization of longitudinal DT-MRI to study white matter maturation of the early developing brain. Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls.

The plant ontology as a tool for comparative plant anatomy and genomic analyses. Generating fibre orientation maps in human heart models using Poisson interpolation. Ontology-based combinatorial comparative analysis of adverse events associated with killed and live influenza vaccines. Muscle contributions to vertical and fore-aft accelerations are altered in subjects with crouch gait.

ArrayExpress update--trends in database growth and links to data analysis tools. PrePPI: a structure-informed database of protein-protein interactions. Toward an understanding of the short bone phenotype associated with multiple osteochondromas. The Measurement of Local Variation in Shape.

A fully implicit finite element method for bidomain models of cardiac electromechanics. Evaluating the predictive value of biomarkers with stratified case-cohort design. Patellar maltracking is prevalent among patellofemoral pain subjects with patella alta: an upright, weightbearing MRI study. Collaborative software for traditional and translational research. Feasibility of studying brain morphology in major depressive disorder with structural magnetic resonance imaging and clinical data from the electronic medical record: a pilot study.

Toe-in gait reduces the first peak knee adduction moment in patients with medial compartment knee osteoarthritis. Differences in subcortical structures in young adolescents at familial risk for schizophrenia: a preliminary study. Longitudinal analysis of pain in patients with metastatic prostate cancer using natural language processing of medical record text.

Diverse types of genetic variation converge on functional gene networks involved in schizophrenia. Localized differences in caudate and hippocampal shape are associated with schizophrenia but not antipsychotic type.

The influence of sodium- and calcium-regulatory hormone interventions on adipocytokines in obesity and diabetes. Broadening instructional scope with network visualization. Mathematical modeling of collagen turnover in biological tissue. Image registration using radial basis functions with adaptive radius. Combing signals from spontaneous reports and electronic health records for detection of adverse drug reactions.

The structural, connectomic and network covariance of the human brain. Knowledge building insights on biomarkers of arsenic toxicity to keratinocytes and melanocytes. Computational modelling of electrocardiograms: repolarisation and T-wave polarity in the human heart. Length distributions of identity by descent reveal fine-scale demographic history.

Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes.

Tor1 regulates protein solubility in Saccharomyces cerevisiae. The structure of the corpus callosum in obsessive compulsive disorder. On removing interpolation and resampling artifacts in rigid image registration. Multicenter reliability of diffusion tensor imaging. Detecting identity by descent and homozygosity mapping in whole-exome sequencing data.

Automated dispersion and orientation analysis for carbon nanotube reinforced polymer composites. A rule based solution to co-reference resolution in clinical text. SHARE: system design and case studies for statistical health information release. Stretching skeletal muscle: chronic muscle lengthening through sarcomerogenesis. An excess of deleterious variants in VEGF-A pathway genes in Down-syndrome-associated atrioventricular septal defects.

A unified inference procedure for a class of measures to assess improvement in risk prediction systems with survival data. Comparative profiling of miRNA expression of lung adenocarcinoma cells in two-dimensional and three-dimensional cultures. LRpath analysis reveals common pathways dysregulated via DNA methylation across cancer types. Antidepressant response in patients with major depression exposed to NSAIDs: a pharmacovigilance study.

Adaptive prior probability and spatial temporal intensity change estimation for segmentation of the one-year-old human brain. Changes in in vivo knee contact forces through gait modification. Terminology representation guidelines for biomedical ontologies in the semantic web notations. Structure-based prediction of protein-protein interactions on a genome-wide scale. Anisotropic conductivity of magnetic carbon nanotubes embedded in epoxy matrices. Neuropsychological variability, symptoms, and brain imaging in chronic schizophrenia.

Imaging nigral pathology and clinical progression in Parkinson's disease. Setting up an intronic miRNA database. Extended Broca's area in the functional connectome of language in adults: combined cortical and subcortical single-subject analysis using fMRI and DTI tractography.

Comprehensive molecular portraits of human breast tumours. Associations between white matter microstructure and infants' working memory. Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter. Global probabilistic annotation of metabolic networks enables enzyme discovery. How much muscle strength is required to walk in a crouch gait?

In-bore setup and software for 3T MRI-guided transperineal prostate biopsy. Calibration of multiple in silico tools for predicting pathogenicity of mismatch repair gene missense substitutions.

Nanoinformatics: developing new computing applications for nanomedicine. Designing a public square for research computing.

Frontiers in growth and remodeling. Utilizing the integrated difference of two survival functions to quantify the treatment contrast for designing, monitoring, and analyzing a comparative clinical study. A gene expression profile of stem cell pluripotentiality and differentiation is conserved across diverse solid and hematopoietic cancers. Translational bioinformatics embraces big data. Contributions of muscles to mediolateral ground reaction force over a range of walking speeds.

North African Jewish and non-Jewish populations form distinctive, orthogonal clusters. Pharmacokinetics and pharmacodynamics of oral artesunate monotherapy in patients with uncomplicated Plasmodium falciparum malaria in western Cambodia. Nonmodulation as the mechanism for salt sensitivity of blood pressure in individuals with hypertension and type 2 diabetes mellitus.

Reduced fractional anisotropy and axial diffusivity in white matter in 22q Large-scale evaluation of automated clinical note de-identification and its impact on information extraction. Emergence of fatal avian influenza in New England harbor seals. Ontologies as integrative tools for plant science. A role for ephrin-A5 in axonal sprouting, recovery, and activity-dependent plasticity after stroke. Leveraging models of cell regulation and GWAS data in integrative network-based association studies.

Mining the pharmacogenomics literature--a survey of the state of the art. A 3D interactive multi-object segmentation tool using local robust statistics driven active contours.

How many neutrophils are enough redux, redux? Comparative protein interactomics of neuroglobin and myoglobin. Wisdom of crowds for robust gene network inference. Human middle longitudinal fascicle: variations in patterns of anatomical connections. Using domain knowledge and domain-inspired discourse model for coreference resolution for clinical narratives.

Context-specific ontology integration: a bayesian approach. Analyzing patterns of drug use in clinical notes for patient safety. Using temporal patterns in medical records to discern adverse drug events from indications. Formal concept analysis of disease similarity. Semantator: annotating clinical narratives with semantic web ontologies. Analysis of high-throughput screening assays using cluster enrichment. Reviewing social media use by clinicians.

Filtering in the diffeomorphism group and the registration of point sets. Genetic correction of Huntington's disease phenotypes in induced pluripotent stem cells.

Identifying genetic marker sets associated with phenotypes via an efficient adaptive score test. Semiparametric Bayesian local functional models for diffusion tensor tract statistics.

The coming age of data-driven medicine: translational bioinformatics' next frontier. Endoscopic image analysis in semantic space. Genetics insights into the pathogenesis of Kawasaki disease. Coreference analysis in clinical notes: a multi-pass sieve with alternate anaphora resolution modules. Active learning for clinical text classification: is it better than random sampling? DEFOG: discrete enrichment of functionally organized genes. Bioinformatics advances in saliva diagnostics.

Characteristics associated with improved knee extension after strength training for individuals with cerebral palsy and crouch gait. A survey of informatics platforms that enable distributed comparative effectiveness research using multi-institutional heterogenous clinical data.

Brain volume findings in 6-month-old infants at high familial risk for autism. Polymorphisms in the serum- and glucocorticoid-inducible kinase 1 gene are associated with blood pressure and renin response to dietary salt intake.

Structural brain atlases: design, rationale, and applications in normal and pathological cohorts. Image registration for targeted MRI-guided transperineal prostate biopsy. Obstetric complications and risk for conversion to psychosis among individuals at high clinical risk.

Template-cut: a pattern-based segmentation paradigm. Towards automatic diabetes case detection and ABCS protocol compliance assessment. Whole brain resting state functional connectivity abnormalities in schizophrenia.

Mapping connectivity damage in the case of Phineas Gage. A supervised framework for resolving coreference in clinical records. Machine learning-based coreference resolution of concepts in clinical documents. Central nervous system endoplasmic reticulum stress in a murine model of type 2 diabetes. Predicting the metabolic cost of incline walking from muscle activity and walking mechanics.

The microRNA expression associated with morphogenesis of breast cancer cells in three-dimensional organotypic culture. Recognition of medication information from discharge summaries using ensembles of classifiers.

Coreference resolution of medical concepts in discharge summaries by exploiting contextual information. Bioinformatics and variability in drug response: a protein structural perspective. Novel data-mining methodologies for adverse drug event discovery and analysis. Evolutionary molecular medicine. Crouched posture maximizes ground reaction forces generated by muscles.

Limbic system white matter microstructure and long-term treatment outcome in major depressive disorder: a diffusion tensor imaging study using legacy data. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

Vitamin D3 therapy corrects the tissue sensitivity to angiotensin ii akin to the action of a converting enzyme inhibitor in obese hypertensives: an interventional study. Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus.

Lysine-specific demethylase 1: an epigenetic regulator of salt-sensitive hypertension. Functional organization and its implication in evolution of the human protein-protein interaction network. An image analysis toolbox for high-throughput C. Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4. The co-morbidity burden of children and young adults with autism spectrum disorders.

Protecting count queries in study design. Quantitative tract-based white matter development from birth to age 2years. A classification approach to coreference in discharge summaries: i2b2 challenge. Structure-based drug screening for G-protein-coupled receptors. Using ontology-based annotation to profile disease research. Unified Medical Language System term occurrences in clinical notes: a large-scale corpus analysis. A patient-driven adaptive prediction technique to improve personalized risk estimation for clinical decision support.

Metab2MeSH: annotating compounds with medical subject headings. Sex matters during adolescence: testosterone-related cortical thickness maturation differs between boys and girls. A mega-analysis of genome-wide association studies for major depressive disorder. Frontostriatal connectivity in children during working memory and the effects of prenatal methamphetamine, alcohol, and polydrug exposure.

Lexical patterns, features and knowledge resources for coreference resolution in clinical notes. Inference of modules associated to eQTLs.

Genome-wide functional annotation of dual-specificity protein- and lipid-binding modules that regulate protein interactions. Prenatal isolated mild ventriculomegaly is associated with persistent ventricle enlargement at ages 1 and 2. The right inhibition? Callosal correlates of hand performance in healthy children and adolescents callosal correlates of hand performance. A review of magnetic resonance imaging and diffusion tensor imaging findings in mild traumatic brain injury.

Structure-based ligand discovery for the protein-protein interface of chemokine receptor CXCR4. Right, left, and center: how does cerebral asymmetry mix with callosal connectivity? Anterior limb of the internal capsule in schizophrenia: a diffusion tensor tractography study.

Hippocampal shape analysis in Alzheimer's disease and frontotemporal lobar degeneration subtypes. Where to Publish and Find Ontologies? A Survey of Ontology Libraries.

White matter integrity, language, and childhood onset schizophrenia. Analytic regularization for landmark-based image registration. How robust is human gait to muscle weakness? Bayesian lasso for semiparametric structural equation models. Portability of an algorithm to identify rheumatoid arthritis in electronic health records. Self-crossing detection and location for parametric active contours. Size and shape of the caudate nucleus in individuals with bipolar affective disorder.

Evaluating the state of the art in coreference resolution for electronic medical records. Square-cut: a segmentation algorithm on the basis of a rectangle shape. Patient-tailored connectomics visualization for the assessment of white matter atrophy in traumatic brain injury. Differences in white matter fiber tract development present from 6 to 24 months in infants with autism. Predictors of severe outcomes associated with Clostridium difficile infection in patients with inflammatory bowel disease.

In search of the functional neuroanatomy of sociality: MRI subdivisions of orbital frontal cortex and social cognition. Hippocampal atrophy and ventricular enlargement in normal aging, mild cognitive impairment MCI , and Alzheimer Disease. Viral reassortment as an information exchange between viral segments. Quantitative modeling of the terminal differentiation of B cells and mechanisms of lymphomagenesis.

Circular representation of human cortical networks for subject and population-level connectomic visualization. A system for coreference resolution for the clinical narrative. Ratcheting up cancer potency estimates. On the covariate-adjusted estimation for an overall treatment difference with data from a randomized comparative clinical trial.

Single sample expression-anchored mechanisms predict survival in head and neck cancer. TwinMARM: two-stage multiscale adaptive regression methods for twin neuroimaging data. Developing predictive molecular maps of human disease through community-based modeling. Diffusion tensor imaging-based characterization of brain neurodevelopment in primates. Classification of astrocytomas and oligodendrogliomas from mass spectrometry data using sparse kernel machines.

A compressive sensing approach for glioma margin delineation using mass spectrometry. Ranking of stopping criteria for log domain diffeomorphic demons application in clinical radiation therapy. Ballistocardiography--a method worth revisiting.

Genetic interactions between chromosomes 11 and 18 contribute to airway hyperresponsiveness in mice. Atlas-guided segmentation of vervet monkey brain MRI. Reverse-engineering human regulatory networks. Disease and genetic contributions toward local tissue volume disturbances in schizophrenia: a tensor-based morphometry study. Clinical application of pharmacokinetic analysis as a biomarker of solitary pulmonary nodules: dynamic contrast-enhanced MR imaging.

How to measure cortical folding from MR images: a step-by-step tutorial to compute local gyrification index. On the biomechanics and mechanobiology of growing skin. Stabilisation of walking by intrinsic muscle properties revealed in a three-dimensional muscle-driven simulation. Technical desiderata for the integration of genomic data into Electronic Health Records.

Using multiple microenvironments to find similar ligand-binding sites: application to kinase inhibitor binding. Quantifying the white blood cell transcriptome as an accessible window to the multiorgan transcriptome. CNTRO 2. Smooth isotonic regression: a new method to calibrate predictive models. Optimized torsion-angle normal modes reproduce conformational changes more accurately than cartesian modes. Compressive tibiofemoral force during crouch gait. Anatomic brain asymmetry in vervet monkeys.

The effect of reference panels and software tools on genotype imputation. Anomaly and signature filtering improve classifier performance for detection of suspicious access to EHRs. Improving predictions in imbalanced data using Pairwise Expanded Logistic Regression. Part-of-speech tagging for clinical text: wall or bridge between institutions? A cloud-based approach to medical NLP.

Registration of images with varying topology using embedded maps. Trends in biomedical informatics: most cited topics from recent years. Neurological imaging: statistics behind the pictures. MicroRNA expression characterizes oligometastasis es. Identifying hosts of families of viruses: a machine learning approach. Grand challenge competition to predict in vivo knee loads.

Cofactor binding evokes latent differences in DNA binding specificity between Hox proteins. Genetic susceptibility to coronary heart disease in type 2 diabetes: 3 independent studies. Empirical comparison of cross-platform normalization methods for gene expression data. Metscape 2 bioinformatics tool for the analysis and visualization of metabolomics and gene expression data.

Phenotyping patient-derived cells for translational studies in cardiovascular disease. Along-tract statistics allow for enhanced tractography analysis. Influence of dietary sodium modulation on electrocardiographic voltage criteria for left ventricular hypertrophy in normotensive individuals. Journal of investigative medicine : the official publication of the American Federation for Clinical Research.

Functional Annotation Analytics of Rhodopseudomonas palustris Genomes. Growing skin: A computational model for skin expansion in reconstructive surgery.

A translational engine at the national scale: informatics for integrating biology and the bedside. Using systems and structure biology tools to dissect cellular phenotypes. Simbios: an NIH national center for physics-based simulation of biological structures. The Center for Computational Biology: resources, achievements, and challenges. The National Center for Biomedical Ontology. The National Alliance for Medical Image Computing, a roadmap initiative to build a free and open source software infrastructure for translational research in medical image analysis.

Replication and meta-analysis of the gene-environment interaction between body mass index and the interleukin-6 promoter polymorphism with higher insulin resistance. Growing skin: tissue expansion in pediatric forehead reconstruction.

Brain growth rate abnormalities visualized in adolescents with autism. A systems view of genetics in chronic kidney disease. Segmentation of nerve bundles and ganglia in spine MRI using particle filters. Geometric metamorphosis. Fast shape-based nearest-neighbor search for brain MRIs using hierarchical feature matching. Iterative refinement of point correspondences for 3D statistical shape models.

Estimation of smooth growth trajectories with controlled acceleration from time series shape data. Geometric correspondence for ensembles of nonregular shapes. A cascade of classifiers for extracting medication information from discharge summaries. A hidden Markov model for copy number variant prediction from whole genome resequencing data.

Strategies for maintaining patient privacy in i2b2. Calibrating predictive model estimates to support personalized medicine. The architecture of long-range haplotypes shared within and across populations. A map of minor groove shape and electrostatic potential from hydroxyl radical cleavage patterns of DNA. Empowering industrial research with shared biomedical vocabularies. Source cancellation profiles of electroencephalography and magnetoencephalography. Cortical and hippocampal atrophy in patients with autosomal dominant familial Alzheimer's disease.

Multiscale computational models for optogenetic control of cardiac function. The identification of gene expression profiles associated with progression of human diabetic neuropathy. Brain surface conformal parameterization with the Ricci flow. Morphometric analysis of subcortical structures in progressive supranuclear palsy: In vivo evidence of neostriatal and mesencephalic atrophy.

ARGOS policy brief on semantic interoperability. Differentially Private Empirical Risk Minimization. Asymmetric bias in user guided segmentations of brain structures.

Search for patterns of functional specificity in the brain: a nonparametric hierarchical Bayesian model for group fMRI data. Robust brain extraction across datasets and comparison with publicly available methods. Joint modeling of anatomical and functional connectivity for population studies. Ontology-based Brucella vaccine literature indexing and systematic analysis of gene-vaccine association network. Modeling diffusion-weighted MRI as a spatially variant gaussian mixture: application to image denoising.

Anatomy of high-performance 2D similarity calculations. Natural language processing: an introduction. Overcoming barriers to NLP for clinical text: the role of shared tasks and the need for additional creative solutions. Differential effects of the Huntington's disease CAG mutation in striatum and cerebellum are quantitative not qualitative. Journal of statistics education : an international journal on the teaching and learning of statistics.

Comparison of two methods for quantitative assessment of mandibular asymmetry using cone beam computed tomography image volumes. Fiber geometry in the corpus callosum in schizophrenia: evidence for transcallosal misconnection. Superimposition of 3D cone-beam CT models in orthognathic surgery. Patients with patellofemoral pain exhibit elevated bone metabolic activity at the patellofemoral joint.

Analysis of the coding genome of diffuse large B-cell lymphoma. Applications of the pipeline environment for visual informatics and genomics computations. Comparison of acute and chronic traumatic brain injury using semi-automatic multimodal segmentation of MR volumes.

Fast flexible modeling of RNA structure using internal coordinates. Quantitative comparison of villin headpiece subdomain simulations and triplet-triplet energy transfer experiments. A generative approach for image-based modeling of tumor growth. White matter bundle registration and population analysis based on Gaussian processes. Learning an atlas of a cognitive process in its functional geometry.

Optimal data-driven sparse parameterization of diffeomorphisms for population analysis. Adaptive Riemannian metrics for improved geodesic tracking of white matter. Developmental cognitive neuroscience : a journal for cognitive, affective and social developmental neuroscience. A knowledge discovery and reuse pipeline for information extraction in clinical notes. The Cardiac Atlas Project--an imaging database for computational modeling and statistical atlases of the heart.

Chronic intestinal inflammation induces stress-response genes in commensal Escherichia coli. Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer. Informatics and standards for nanomedicine technology. This cemetery on the grounds of Carlisle Barracks holds the remains of students from the former Carlisle Indian Industrial School. Army War College Photo Lab hide caption. Seeing Ghosts , a memoir by Kat Chow. Grand Central Publishing hide caption.

In her memoir, Seeing Ghosts , the author and former Code Switch reporter explores how her mother's death has haunted her through the years, in ways that are profound, tragic and, sometimes, darkly hilarious.

But they're all students, they're all amazing, and frankly, we're concerned that they might be coming for our jobs. That's right — the Student Podcast Challenge is back, and this year, the stories are more powerful than ever. So in the spirit of spicing things up, we wanted to give you all a question to fight about: How much context should you have to give when talking about race and culture?

Is it better to explain every reference, or ask people to Google as they go? Comedian Hari Kondabolu joins us to hash it out. But there is so much police violence that falls short of being fatal, but forever alters the lives of the people on the business end of it. Helen Hoang, author of The Kiss Quotient. Eric Kieu hide caption. Today, we're in conversation with a romance novelist whose own identity helped inform a rich cast of characters.

Somebody's Daughter , by Ashley C. In her new memoir, Somebody's Daughter, Ford looks at how her upbringing shaped her understanding of childhood, authority, forgiveness and freedom. Accessibility links Skip to main content Keyboard shortcuts for audio player.

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Talk all about them here! Tech Show Central The one-stop forum for everything and anything related to the local tech shows! Android TV Box. Yesterday at AM TonyStark. InfoTech Clinics www. Popular topics include computer set-up, configuration, tweaking, processors, motherboards, graphics cards, monitors, SSD, hard drives, NAS, speakers, printers, input devices and more! Threads Is Cat 5e Lan cable still relevant? A moment ago Clearnfc. Discussions include hardware and technical-related issues.

Threads 5. Laptop Advice for Work. Today at AM yusoffb ISP plans, decisions and feedback? Optimizing connection speed? Wired and Wireless Networking queries? If it's about broadband, internet bandwidth and networking, it's HERE. Threads 9. Today at AM linwenquan Welcome to Apple Haven. Threads 8. Today at AM xiaosen. Threads 3. Import songs from remote CD drive into iTunes. Gaming Arena The one forum for all gaming discussions!

Whether you're a PlayStation, Xbox, Nintendo console fan or a PC, handheld, smartphone gamer, level up your game, share your tips and tricks, discuss which game port is superior or hire new teammates for your gaming session - this forum is THE home for all things gaming. Game on! In collaboration with. Today at AM SmartVanquisher. Yesterday at PM eltonhjohn1. Discuss all about AV Recievers, amplifiers, speakers, blu-ray players, media players and more! Today at AM SyncGuy. Headphones, Earphones and Portable Media Devices These personal listening equipment are very important with the ever-growing variety of portable media consumption devices like phones, tablets, PMPs, etc.

Threads 4. Soundcore Liberty 3 pro TWS earbuds. The Tablet Den Share and discuss everything related to the growing popularity of tablet devices here, from iPads to the many Android tablets! This is the one stop place for you tablet lovers! Sub-forums: The iPad Sanctum. China Tablets to recommend. Threads 2K Messages Where to buy IR filter in SG?

Yesterday at PM shadey. Pocophone F3. Wearable Gadgets and IoT Share your experience of this growing but personal tech segment that aims to enhance and fit seamlessly in your lives with fitness trackers, smart watches, smart glasses, and other wearable gizmos that form a bigger group of Internet of Things IoT. Syncing steps with Healthy app. Yesterday at PM Warrenw1.

Special Interest Groups SiGs for you to share your experience and knowledge on special focus areas. Hobby Lovers Have an interesting pastime to share? Threads 7. Sub-forums: Hobbyists' Bazaar.

Ask a Bicycle Question - Part 6. Today at AM chopra. The Book Nook For all you book lovers and aspiring writers, here's your own forum to share and seek thoughts and opinions on books and literary works.

Review novels, cook books or even reference books, discuss poetry style or improve writing techniques. Which are some of the better online bookstores you guys use? Yesterday at PM flowerpalms. Yesterday at AM deathan9el. Threads Messages 2.

Graphic designing. Jun 21, girlfromthemoon. Wanna upgrade and reduce expense thru sale of old belongings? Threads Messages 4K. Threads Messages 3. Master and Dynamic MW65 wireless noise cancelling headphones silver metal brown leather. Clothings, jewellery, accessories, facial products, spa package, movie tickets, concert tickets and almost everything else. Today at AM starryskiesx. Mass Order Corner Looking for collective purchase of your dream gadget? Or eyeing exotic items from overseas but not willing to pay the shipping cost?

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Sub-forums: Pets' Barter Corner. Yesterday at PM Apparatus. Comparing 3T and 1. BrainPrint: a discriminative characterization of brain morphology.

Cloud computing approaches for prediction of ligand binding poses and pathways. Analyzing search behavior of healthcare professionals for drug safety surveillance. Single-molecule dataset SMD : a generalized storage format for raw and processed single-molecule data. Overcome support vector machine diagnosis overfitting.

A novel genome-wide significant locus on chromosome 2 near ASB3. Medial frontal white and gray matter contributions to general intelligence. Epileptogenic focus localization in treatment-resistant post-traumatic epilepsy. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. RELAX: detecting relaxed selection in a phylogenetic framework. Genotype to phenotype relationships in autism spectrum disorders. Scalable privacy-preserving data sharing methodology for genome-wide association studies: an application to iDASH healthcare privacy protection challenge.

Differentially private genome data dissemination through top-down specialization. A community assessment of privacy preserving techniques for human genomes. Longitudinal quantification and visualization of intracerebral haemorrhage using multimodal magnetic resonance and diffusion tensor imaging.

Segmentation of cerebrovascular pathologies in stroke patients with spatial and shape priors. Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia. Is my model good enough?

Best practices for verification and validation of musculoskeletal models and simulations of movement. Multi-modal robust inverse-consistent linear registration. Differences in muscle activity between natural forefoot and rearfoot strikers during running. Integration of genomic data enables selective discovery of breast cancer drivers. Comment on: ''Zoo or savannah? Choice of training ground for evidence-based pharmacovigilance''. Multimodal neuroimaging feature learning for multiclass diagnosis of Alzheimer's disease.

A community computational challenge to predict the activity of pairs of compounds. Discovering chemistry with an ab initio nanoreactor. Text mining in cancer gene and pathway prioritization. Statistical estimation of physiological brain age as a descriptor of senescence rate during adulthood. Long-term phenotypic evolution of bacteria.

The genetic basis of chronic mountain sickness. ArrayExpress update--simplifying data submissions. Choosing blindly but wisely: differentially private solicitation of DNA datasets for disease marker discovery.

Disease Ontology update: an expanded and updated database of human diseases for linking biomedical knowledge through disease data. Automatic identification of methotrexate-induced liver toxicity in patients with rheumatoid arthritis from the electronic medical record. Computational modeling of hypertensive growth in the human carotid artery.

Systems biology. Conditional density-based analysis of T cell signaling in single-cell data. The DTI connectivity of the human claustrum. Functional evaluation of out-of-the-box text-mining tools for data-mining tasks. Interrogation of a context-specific transcription factor network identifies novel regulators of pluripotency. Atlas-based under-segmentation. Gaussian process interpolation for uncertainty estimation in image registration.

Diffeomorphic shape trajectories for improved longitudinal segmentation and statistics. BrainPrint: identifying subjects by their brain. Subject-specific prediction using nonlinear population modeling: application to early brain maturation from DTI. Hierarchical bayesian modeling, estimation, and sampling for multigroup shape analysis. Evolving insights on how cytosine methylation affects protein-DNA binding.

Inferring protein modulation from gene expression data using conditional mutual information. Cingulum bundle integrity associated with delusions of control in schizophrenia: Preliminary evidence from diffusion-tensor tractography.

Characterizing growth patterns in longitudinal MRI using image contrast. Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks.

International Conference on Machine Learning. Predicting accurate probabilities with a ranking loss. Machine learning : proceedings of the International Conference.

Abstractions for Genomics. The Living Heart Project: A robust and integrative simulator for human heart function. Multivariate longitudinal shape analysis of human lateral ventricles during the first twenty-four months of life. IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform. Computational modeling of skin: Using stress profiles as predictor for tissue necrosis in reconstructive surgery.

Mode of childbirth and long-term outcomes in women with inflammatory bowel diseases. Co-regulated transcripts associated to cooperating eSNPs define Bi-fan motifs in human gene networks.

Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins.

The role of mechanics during brain development. Use it or lose it: multiscale skeletal muscle adaptation to mechanical stimuli. Sparse kernel machine regression for ordinal outcomes. Pegasus: a comprehensive annotation and prediction tool for detection of driver gene fusions in cancer.

Decoupling function and anatomy in atlases of functional connectivity patterns: language mapping in tumor patients. Comparative analysis of metazoan chromatin organization. In search of the determinants of enhancer-promoter interaction specificity. Prenatal antidepressant exposure is associated with risk for attention-deficit hyperactivity disorder but not autism spectrum disorder in a large health system. SELEX-seq: a method for characterizing the complete repertoire of binding site preferences for transcription factor complexes.

Complex pathways in folding of protein G explored by simulation and experiment. Evolution of the central sulcus morphology in primates. Treatment selections using risk-benefit profiles based on data from comparative randomized clinical trials with multiple endpoints.

Multiple LacI-mediated loops revealed by Bayesian statistics and tethered particle motion. Classification of CT pulmonary angiography reports by presence, chronicity, and location of pulmonary embolism with natural language processing. Differentially private distributed logistic regression using private and public data. Data-driven discovery of seasonally linked diseases from an Electronic Health Records system.

Multi-atlas segmentation with particle-based group-wise image registration. Impact of family history on prostate cancer mortality in white men undergoing prostate specific antigen based screening. Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records. Lipoprotein particle concentrations in children and adults following Kawasaki disease. An autism case history to review the systematic analysis of large-scale data to refine the diagnosis and treatment of neuropsychiatric disorders.

Robust Radiomics feature quantification using semiautomatic volumetric segmentation. Characterization of living skin using multi-view stereo and isogeometric analysis. Privacy preserving RBF kernel support vector machine. A mechanical model predicts morphological abnormalities in the developing human brain. Localized abnormalities in the cingulum bundle in patients with schizophrenia: a Diffusion Tensor tractography study.

Prenatal cocaine effects on brain structure in early infancy. Toward personalizing treatment for depression: predicting diagnosis and severity. ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2. Morphometry of anatomical shape complexes with dense deformations and sparse parameters. Characterizing a collective and dynamic component of chromatin immunoprecipitation enrichment profiles in yeast. The elusive evidence for chromothripsis. Harnessing natural sequence variation to dissect posttranscriptional regulatory networks in yeast.

Multi-Channel neurodegenerative pattern analysis and its application in Alzheimer's disease characterization. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. Inferring gene ontologies from pairwise similarity data. Dysmorphogenic effects of first trimester-equivalent ethanol exposure in mice: a magnetic resonance microscopy-based study.

Fluoroquinolone resistant rectal colonization predicts risk of infectious complications after transrectal prostate biopsy. Integrative biology identifies shared transcriptional networks in CKD. OpenIGTLink interface for state control and visualisation of a robot for image-guided therapy systems.

MAGI: a Node. Structural bioinformatics of the interactome. A community effort to assess and improve drug sensitivity prediction algorithms. Natural language processing in biomedicine: a unified system architecture overview. Evaluating the effects of machine pre-annotation and an interactive annotation interface on manual de-identification of clinical text. Transfer learning based clinical concept extraction on data from multiple sources.

Structural and connectomic neuroimaging for the personalized study of longitudinal alterations in cortical shape, thickness and connectivity after traumatic brain injury. Meshless Modeling of Deformable Shapes and their Motion. Patient-level temporal aggregation for text-based asthma status ascertainment. Efficient inverse isoparametric mapping algorithm for whole-body computed tomography registration using deformations predicted by nonlinear finite element modeling.

Response of Escherichia coli growth rate to osmotic shock. A graph algebra for scalable visual analytics. Multiatlas segmentation as nonparametric regression. Coping with confounds in multivoxel pattern analysis: what should we do about reaction time differences? Automatic segmentation of head and neck CT images for radiotherapy treatment planning using multiple atlases, statistical appearance models, and geodesic active contours. Evaluating marker-guided treatment selection strategies.

Variations of dynamic contrast-enhanced magnetic resonance imaging in evaluation of breast cancer therapy response: a multicenter data analysis challenge. Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development.

Knowledge-based fragment binding prediction. A complete system for automatic extraction of left ventricular myocardium from CT images using shape segmentation and contour evolution. Ensuring privacy in the study of pathogen genetics. Mutual information as a measure of image quality for 3D dynamic lung imaging with EIT. Identifying regulatory mechanisms underlying tumorigenesis using locus expression signature analysis. Response to letters regarding article, "unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine".

Population-level evidence for an autoimmune etiology of epilepsy. Joint modeling of imaging and genetics. Geodesic shape regression in the framework of currents. Bayesian segmentation of atrium wall using globally-optimal graph cuts on 3D meshes.

Group-wise cortical correspondence via sulcal curve-constrained entropy minimization. Sparse projections of medical images onto manifolds. A longitudinal functional analysis framework for analysis of white matter tract statistics.

Aldosterone dysregulation with aging predicts renal vascular function and cardiovascular risk. Bayesian energy landscape tilting: towards concordant models of molecular ensembles. Empirical Bayes methods enable advanced population-level analyses of single-molecule FRET experiments. Developing image processing meta-algorithms with data mining of multiple metrics.

Cerebral white matter abnormalities and their associations with negative but not positive symptoms of schizophrenia. Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases. Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma. High precision prediction of functional sites in protein structures.

MAAMD: a workflow to standardize meta-analyses and comparison of affymetrix microarray data. Neuroinformatics challenges to the structural, connectomic, functional and electrophysiological multimodal imaging of human traumatic brain injury.

Changes in tibiofemoral forces due to variations in muscle activity during walking. Pregnancy in women with a history of Kawasaki disease: management and outcomes. Semantics in support of biodiversity knowledge discovery: an introduction to the biological collections ontology and related ontologies.

The automated function prediction SIG looks back at and prepares for Automated detection of off-label drug use. Multifold Bayesian kernelization in Alzheimer's diagnosis. Geodesic distances to landmarks for dense correspondence on ensembles of complex shapes.

Systematic network lesioning reveals the core white matter scaffold of the human brain. Multi-atlas segmentation of subcortical brain structures via the AutoSeg software pipeline. SAVI: a statistical algorithm for variant frequency identification. On the mechanics of growing thin biological membranes. Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease.

Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes. When you can't tell when it hurts: a preliminary algorithm to assess pain in patients who can't communicate. Crowdsourcing the verification of relationships in biomedical ontologies. Building and evaluating an ontology-based tool for reasoning about consent permission. Effects of polymerization and nucleotide identity on the conformational dynamics of the bacterial actin homolog MreB.

Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness. Annotating the structure and components of a nanoparticle formulation using computable string expressions. Rare copy number variation in treatment-resistant major depressive disorder. DTIPrep: quality control of diffusion-weighted images. Semi-Automatic Parcellation of the Corpus Striatum. Validation of catheter segmentation for MR-guided gynecologic cancer brachytherapy.

Contour-driven regression for label inference in atlas-based segmentation. Particle-guided image registration. Detecting epileptic regions based on global brain connectivity patterns. Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia.

Specificity of regulatory T cells that modulate vascular inflammation. Differential privacy based on importance weighting. Web-based tools for modelling and analysis of multivariate data: California ozone pollution activity. More accurate neuronavigation data provided by biomechanical modeling instead of rigid registration.

MutPred Splice: machine learning-based prediction of exonic variants that disrupt splicing. Word sense disambiguation in the clinical domain: a comparison of knowledge-rich and knowledge-poor unsupervised methods.

Automatic lymphoma classification with sentence subgraph mining from pathology reports. Regional neuroplastic brain changes in patients with chronic inflammatory and non-inflammatory visceral pain. A midas plugin to enable construction of reproducible web-based image processing pipelines. Serum inflammatory markers and risk of colorectal cancer in patients with inflammatory bowel diseases. A framework for longitudinal data analysis via shape regression. Fast approximate surface evolution in arbitrary dimension.

Studying PubMed usages in the field for complex problem solving: Implications for tool design. Atrial fibrillation ablation outcome is predicted by left atrial remodeling on MRI. Stochastic Image Registration with User Constraints. Fiber feature map based landmark initialization for highly deformable DTI registration. Quality Control of Diffusion Weighted Images. The environment ontology: contextualising biological and biomedical entities. Omnibus risk assessment via accelerated failure time kernel machine modeling.

Treatment response in kawasaki disease is associated with sialylation levels of endogenous but not therapeutic intravenous immunoglobulin G. Comorbidity clusters in autism spectrum disorders: an electronic health record time-series analysis. Mining the ultimate phenome repository. The neurological disease ontology. Discussion of ''Biomedical informatics: we are what we publish''. Amplification and thrifty single-molecule sequencing of recurrent somatic structural variations.

Genome-wide DNA methylation changes with age in disease free human skeletal muscle. Calculations of the electric fields in liquid solutions. Learning signals of adverse drug-drug interactions from the unstructured text of electronic health records. Network analysis of unstructured EHR data for clinical research. Profiling risk factors for chronic uveitis in juvenile idiopathic arthritis: a new model for EHR-based research. Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity.

Associations of smoking and alcohol consumption with disease activity and functional status in rheumatoid arthritis. Predicting the restricted mean event time with the subject's baseline covariates in survival analysis. Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia. Genetic robustness and functional evolution of gene duplicates.

Three-dimensional treatment outcomes in Class II patients treated with the Herbst appliance: a pilot study. Chronology of your health events: approaches to extracting temporal relations from medical narratives. OnTheFly: a database of Drosophila melanogaster transcription factors and their binding sites.

SGPP: spatial Gaussian predictive process models for neuroimaging data. State of the human proteome in as viewed through PeptideAtlas: comparing the kidney, urine, and plasma proteomes for the biology- and disease-driven Human Proteome Project.

Reviewing the ketamine model for schizophrenia. Modeling disease severity in multiple sclerosis using electronic health records. Growing matter: a review of growth in living systems. Predictors of plasma and urinary catecholamine levels in normotensive and hypertensive men and women. Towards generating a patient's timeline: extracting temporal relationships from clinical notes. Improved segmentation of white matter tracts with adaptive Riemannian metrics.

In silico approaches and the role of ontologies in aging research. Using search queries for malaria surveillance, Thailand. Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome. Three-dimensional analysis of maxillary changes associated with facemask and rapid maxillary expansion compared with bone anchored maxillary protraction.

Neuroimaging of structural pathology and connectomics in traumatic brain injury: Toward personalized outcome prediction. Topology of viral evolution. Regional 3D superimposition to assess temporomandibular joint condylar morphology. Leveraging electronic health records to notify pediatric patients of a drug recall. Mining clinical text for signals of adverse drug-drug interactions. Application of universal stress proteins in probing the dynamics of potent degraders in complex terephthalate metagenome.

Automated chart review for asthma cohort identification using natural language processing: an exploratory study. Nocturnal continuous glucose and sleep stage data in adults with type 1 diabetes in real-world conditions. Human neuroimaging as a "Big Data" science. Distinct splice variants and pathway enrichment in the cell-line models of aggressive human breast cancer subtypes. Localized Sparse Code Gradient in Alzheimer's disease staging.

Conference proceedings Annual Conference. Nucleotide sequence alignment using sparse coding and belief propagation. Discovering body site and severity modifiers in clinical texts. Improved de-identification of physician notes through integrative modeling of both public and private medical text.

Temporal relation discovery between events and temporal expressions identified in clinical narrative. FMEM: functional mixed effects modeling for the analysis of longitudinal white matter Tract data. A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk. Neural encoding of acupuncture needling sensations: evidence from a FMRI study. Seasonality of Kawasaki disease: a global perspective.

Instrumentation bias in the use and evaluation of scientific software: recommendations for reproducible practices in the computational sciences. Automatic segmentation of the left atrium from MR images via variational region growing with a moments-based shape prior. Combining an expert-based medical entity recognizer to a machine-learning system: methods and a case study. Opportunities for genomic clinical decision support interventions. A novel strategy to identify the critical conditions for growth-induced instabilities.

Temporomandibular joint condylar changes following maxillomandibular advancement and articular disc repositioning. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. Sex-related differences of cortical thickness in patients with chronic abdominal pain. On the design of clone-based haplotyping. A molecular signature predictive of indolent prostate cancer.

Extraction of events and temporal expressions from clinical narratives. Tissue-specific profiling reveals transcriptome alterations in Arabidopsis mutants lacking morphological phenotypes. Assessment of biomarkers for risk prediction with nested case-control studies. Electroencephalographic inverse localization of brain activity in acute traumatic brain injury as a guide to surgery, monitoring and treatment. A new tool for sharing and querying of clinical documents modeled using HL7 Version 3 standard.

Prostate cancer detection and diagnosis: the role of MR and its comparison with other diagnostic modalities--a radiologist's perspective. Automated skin segmentation in ultrasonic evaluation of skin toxicity in breast cancer radiotherapy.

Using twitter to examine smoking behavior and perceptions of emerging tobacco products. PhenDisco: phenotype discovery system for the database of genotypes and phenotypes. Virmid: accurate detection of somatic mutations with sample impurity inference. Identification of Functional Regulatory Residues of the? Automatic prediction of rheumatoid arthritis disease activity from the electronic medical records. On the effect of prestrain and residual stress in thin biological membranes.

Multimodal deformable registration of traumatic brain injury MR volumes via the Bhattacharyya distance. Toward a comprehensive framework for the spatiotemporal statistical analysis of longitudinal shape data.

Identifying phenotypic signatures of neuropsychiatric disorders from electronic medical records. Classifying temporal relations in clinical data: A hybrid, knowledge-rich approach.

Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders. Mapping cortical atrophy in Parkinson's disease patients with dementia. Lipid and lipoprotein levels and trend in rheumatoid arthritis compared to the general population. Extending the NegEx lexicon for multiple languages. ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer.

The integrated landscape of driver genomic alterations in glioblastoma. Shape abnormalities of the caudate nucleus correlate with poorer gait and balance: results from a subset of the LADIS study. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Magnetic resonance microscopy-based analyses of the neuroanatomical effects of gestational day 9 ethanol exposure in mice. MedTime: a temporal information extraction system for clinical narratives. Syntactic parsing of clinical text: guideline and corpus development with handling ill-formed sentences. Immune-monitoring in Kawasaki disease patients treated with infliximab and intravenous immunoglobulin. A locally adaptive regularization based on anisotropic diffusion for deformable image registration of sliding organs.

Interactive medical image segmentation using PDE control of active contours. Localizing the human primary auditory cortex in vivo using structural MRI. Fast local trust region technique for diffusion tensor registration using exact reorientation and regularization. Annotating temporal information in clinical narratives.

Semantator: Semantic annotator for converting biomedical text to linked data. From connectivity models to region labels: identifying foci of a neurological disorder. Computational semantics in clinical text. Longitudinal image registration with temporally-dependent image similarity measure.

Variants in exons and in transcription factors affect gene expression in trans. Ground state destabilization by anionic nucleophiles contributes to the activity of phosphoryl transfer enzymes. Statistical shape modeling of cam femoroacetabular impingement. Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine. Sarcomere lengths in human extensor carpi radialis brevis measured by microendoscopy.

Inference of historical migration rates via haplotype sharing. Improving data and knowledge management to better integrate health care and research. Adopting nested case-control quota sampling designs for the evaluation of risk markers. Decreased axial diffusivity within language connections: A possible biomarker of schizophrenia risk. Sparse texture active contour. Computational modeling of chemo-electro-mechanical coupling: a novel implicit monolithic finite element approach.

Increased gray matter diffusion anisotropy in patients with persistent post-concussive symptoms following mild traumatic brain injury. Privacy technology to support data sharing for comparative effectiveness research: a systematic review. Long-term 3-dimensional stability of mandibular advancement surgery. Using Genome Query Language to uncover genetic variation. Systematic improvement of a classical molecular model of water.

Mechanical consequences of cell-wall turnover in the elongation of a Gram-positive bacterium. Forward and inverse electroencephalographic modeling in health and in acute traumatic brain injury. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. Automatic delineation of the myocardial wall from CT images via shape segmentation and variational region growing.

Hypothalamic proteoglycan syndecan-3 is a novel cocaine addiction resilience factor. Evaluating genome architecture of a complex region via generalized bipartite matching. Extracting physician group intelligence from electronic health records to support evidence based medicine. Dynamic Active Contours for Visual Tracking. Spatial-temporal atlas of human fetal brain development during the early second trimester. Practice-based evidence: profiling the safety of cilostazol by text-mining of clinical notes.

Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls. A rolling constraint reproduces ground reaction forces and moments in dynamic simulations of walking, running, and crouch gait. Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway.

Inferences on the biochemical and environmental regulation of universal stress proteins from Schistosomiasis parasites. Impact of sex and gonadal steroids on neonatal brain structure. Morse-Smale Regression. Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America.

A flexible framework for recognizing events, temporal expressions, and temporal relations in clinical text. Human middle longitudinal fascicle: segregation and behavioral-clinical implications of two distinct fiber connections linking temporal pole and superior temporal gyrus with the angular gyrus or superior parietal lobule using multi-tensor tractography.

Diffusion imaging quality control via entropy of principal direction distribution. Temporal reasoning over clinical text: the state of the art. Beyond NPM-anaplastic lymphoma kinase driven lymphomagenesis: alternative drivers in anaplastic large cell lymphoma. Improving breast cancer survival analysis through competition-based multidimensional modeling.

Reprever: resolving low-copy duplicated sequences using template driven assembly. HIV infection reveals widespread expansion of novel centromeric human endogenous retroviruses.

Surgery, virtual reality, and the future. Enhanced modeling via network theory: Adaptive sampling of Markov state models. Growth on demand: Reviewing the mechanobiology of stretched skin. Optical flow estimation for flame detection in videos. Genetic contributions to changes of fiber tracts of ventral visual stream in 22q Lateral ventricle morphology analysis via mean latitude axis. On the mechanics of continua with boundary energies and growing surfaces.

Combining rules and machine learning for extraction of temporal expressions and events from clinical narratives. Heterogeneity of tumor-induced gene expression changes in the human metabolic network. Innovations in proteomic profiling of cancers: alternative splice variants as a new class of cancer biomarker candidates and bridging of proteomics with structural biology.

Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer. Dominant effects of the Huntington's disease HTT CAG repeat length are captured in gene-expression data sets by a continuous analysis mathematical modeling strategy. Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver. Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

Towards improved ultrasound-based analysis and 3D visualization of the fetal brain using the 3D Slicer. Eventual situations for timeline extraction from clinical reports.

A hybrid system for temporal information extraction from clinical text. Pharmacovigilance using clinical notes. Performance of pharmacovigilance signal-detection algorithms for the FDA adverse event reporting system. Diffusion weighted imaging of prefrontal cortex in prodromal huntington's disease.

Evaluating temporal relations in clinical text: i2b2 Challenge. A controlled greedy supervised approach for co-reference resolution on clinical text. Comprehensive temporal information detection from clinical text: medical events, time, and TLINK identification.

Natural Language Processing to identify pneumonia from radiology reports. The stationary configuration of the knee. MutComFocal: an integrative approach to identifying recurrent and focal genomic alterations in tumor samples.

An informational framework to predict reaction of constraints using a reciprocally connected knee model. An algorithmic approach for breakage-fusion-bridge detection in tumor genomes. Six-week gait retraining program reduces knee adduction moment, reduces pain, and improves function for individuals with medial compartment knee osteoarthritis. Landmark risk prediction of residual life for breast cancer survival.

Differential expression of miR in children with Kawasaki disease. How muscle fiber lengths and velocities affect muscle force generation as humans walk and run at different speeds. An end-to-end system to identify temporal relation in discharge summaries: i2b2 challenge.

Web-scale pharmacovigilance: listening to signals from the crowd. Automating the study of population variation of electrocardiographic features. Referent tracking for treatment optimisation in schizophrenic patients: A case study in applying philosophical ontology to diagnostic algorithms. Stretching skin: The physiological limit and beyond. GBM volumetry using the 3D Slicer medical image computing platform. Flexing computational muscle: modeling and simulation of musculotendon dynamics.

Comparison of four prediction models to discriminate benign from malignant vertebral compression fractures according to MRI feature analysis. From single nucleotide polymorphism to transcriptional mechanism: a model for FRMD3 in diabetic nephropathy. MetaSeq: privacy preserving meta-analysis of sequencing-based association studies.

Insights into diseases of human telomerase from dynamical modeling. Molecular dynamics simulations for the ranking, evaluation, and refinement of computationally designed proteins. Wessim: a whole-exome sequencing simulator based on in silico exome capture.

N-glycoproteome of E Tg2a mouse embryonic stem cells. One-year assessment of surgical outcomes in Class III patients using cone beam computed tomography. Abnormal aldosterone physiology and cardiometabolic risk factors. Classic "broken cell" techniques and newer live cell methods for cell cycle assessment.

Properties of cell death models calibrated and compared using Bayesian approaches. Detecting concept relations in clinical text: insights from a state-of-the-art model. Recursive feature elimination for brain tumor classification using desorption electrospray ionization mass spectrometry imaging. Automatic segmentation of the left atrium from MRI images using salient feature and contour evolution.

Quantifying pathogen surveillance using temporal genomic data. QT interval and antidepressant use: a cross sectional study of electronic health records. Gene expression alterations in bipolar disorder postmortem brains. Multiscale adaptive generalized estimating equations for longitudinal neuroimaging data. Evaluation of methods for modeling transcription factor sequence specificity. A large-scale evaluation of computational protein function prediction.

Federated queries of clinical data repositories: the sum of the parts does not equal the whole. White matter fractional anisotropy is inversely related to anxious symptoms in older adults with atherosclerosis. Similar risk of depression and anxiety following surgery or hospitalization for Crohn's disease and ulcerative colitis. Exact statistical tests for the intersection of independent lists of genes. Systems-based approaches toward wound healing.

Sexually dimorphic white matter geometry abnormalities in adolescent onset schizophrenia. Selecting cases for whom additional tests can improve prognostication. Towards mechanism classifiers: expression-anchored Gene Ontology signature predicts clinical outcome in lung adenocarcinoma patients. Towards the creation of a visual ontology of biomedical imaging entities. The relationship between structural characteristics of challenge documents and ratings of document quality.

Applications of ontology design patterns in biomedical ontologies. A semi-automated quantification of pulmonary artery dimensions in computed tomography angiography images.

Chapter 9: Analyses using disease ontologies. Abnormalities of middle longitudinal fascicle and disorganization in patients with schizophrenia. Psychiatric co-morbidity is associated with increased risk of surgery in Crohn's disease.

Learning a reliable estimate of the number of fiber directions in diffusion MRI. Spectral label fusion. Longitudinal image registration with non-uniform appearance change. Topology preserving atlas construction from shape data without correspondence using sparse parameters.

Metamorphic geodesic regression. Group analysis of resting-state fMRI by hierarchical Markov random fields. A feature-based developmental model of the infant brain in structural MRI. Fast diffusion tensor registration with exact reorientation and regularization.

Analytic regularization of uniform cubic B-spline deformation fields. Analysis of longitudinal shape variability via subject specific growth modeling.

From brain connectivity models to identifying foci of a neurological disorder. Common variants in psychiatric risk genes predict brain structure at birth. MicroRNA-centric measurement improves functional enrichment analysis of co-expressed and differentially expressed microRNA clusters.

Regionally selective atrophy of subcortical structures in prodromal HD as revealed by statistical shape analysis. OntoMaton: a bioportal powered ontology widget for Google Spreadsheets. The variance of identity-by-descent sharing in the Wright-Fisher model. Subgroup specific incremental value of new markers for risk prediction.

Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis. A chromosome-centric human proteome project C-HPP to characterize the sets of proteins encoded in chromosome Tissue plasminogen activator prevents mortality from sulfur mustard analog-induced airway obstruction. Fiber tractography based on diffusion tensor imaging compared with high-angular-resolution diffusion imaging with compressed sensing: initial experience.

Evaluating incremental values from new predictors with net reclassification improvement in survival analysis. To share or not to share: that is not the question. Muscle contributions to fore-aft and vertical body mass center accelerations over a range of running speeds. Sharing data for the public good and protecting individual privacy: informatics solutions to combine different goals.

Privacy-preserving heterogeneous health data sharing. Pituitary adenoma volumetry with 3D Slicer. To milliseconds and beyond: challenges in the simulation of protein folding. Regional characterization of longitudinal DT-MRI to study white matter maturation of the early developing brain.

Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls.

The plant ontology as a tool for comparative plant anatomy and genomic analyses. Generating fibre orientation maps in human heart models using Poisson interpolation. Ontology-based combinatorial comparative analysis of adverse events associated with killed and live influenza vaccines. Muscle contributions to vertical and fore-aft accelerations are altered in subjects with crouch gait.

ArrayExpress update--trends in database growth and links to data analysis tools. PrePPI: a structure-informed database of protein-protein interactions. Toward an understanding of the short bone phenotype associated with multiple osteochondromas.

The Measurement of Local Variation in Shape. A fully implicit finite element method for bidomain models of cardiac electromechanics. Evaluating the predictive value of biomarkers with stratified case-cohort design. Patellar maltracking is prevalent among patellofemoral pain subjects with patella alta: an upright, weightbearing MRI study.

Collaborative software for traditional and translational research. Feasibility of studying brain morphology in major depressive disorder with structural magnetic resonance imaging and clinical data from the electronic medical record: a pilot study. Toe-in gait reduces the first peak knee adduction moment in patients with medial compartment knee osteoarthritis. Differences in subcortical structures in young adolescents at familial risk for schizophrenia: a preliminary study.

Longitudinal analysis of pain in patients with metastatic prostate cancer using natural language processing of medical record text. Diverse types of genetic variation converge on functional gene networks involved in schizophrenia.

Localized differences in caudate and hippocampal shape are associated with schizophrenia but not antipsychotic type. The influence of sodium- and calcium-regulatory hormone interventions on adipocytokines in obesity and diabetes. Broadening instructional scope with network visualization. Mathematical modeling of collagen turnover in biological tissue. Image registration using radial basis functions with adaptive radius. Combing signals from spontaneous reports and electronic health records for detection of adverse drug reactions.

The structural, connectomic and network covariance of the human brain. Knowledge building insights on biomarkers of arsenic toxicity to keratinocytes and melanocytes. Computational modelling of electrocardiograms: repolarisation and T-wave polarity in the human heart. Length distributions of identity by descent reveal fine-scale demographic history. Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes.

Tor1 regulates protein solubility in Saccharomyces cerevisiae. The structure of the corpus callosum in obsessive compulsive disorder. On removing interpolation and resampling artifacts in rigid image registration. Multicenter reliability of diffusion tensor imaging.

Detecting identity by descent and homozygosity mapping in whole-exome sequencing data. Automated dispersion and orientation analysis for carbon nanotube reinforced polymer composites. A rule based solution to co-reference resolution in clinical text.

SHARE: system design and case studies for statistical health information release. Stretching skeletal muscle: chronic muscle lengthening through sarcomerogenesis. An excess of deleterious variants in VEGF-A pathway genes in Down-syndrome-associated atrioventricular septal defects. A unified inference procedure for a class of measures to assess improvement in risk prediction systems with survival data.

Comparative profiling of miRNA expression of lung adenocarcinoma cells in two-dimensional and three-dimensional cultures. LRpath analysis reveals common pathways dysregulated via DNA methylation across cancer types. Antidepressant response in patients with major depression exposed to NSAIDs: a pharmacovigilance study. Adaptive prior probability and spatial temporal intensity change estimation for segmentation of the one-year-old human brain.

Changes in in vivo knee contact forces through gait modification. Terminology representation guidelines for biomedical ontologies in the semantic web notations. Structure-based prediction of protein-protein interactions on a genome-wide scale. Anisotropic conductivity of magnetic carbon nanotubes embedded in epoxy matrices. Neuropsychological variability, symptoms, and brain imaging in chronic schizophrenia. Imaging nigral pathology and clinical progression in Parkinson's disease.

Setting up an intronic miRNA database. Extended Broca's area in the functional connectome of language in adults: combined cortical and subcortical single-subject analysis using fMRI and DTI tractography. Comprehensive molecular portraits of human breast tumours. Associations between white matter microstructure and infants' working memory. Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter.

Global probabilistic annotation of metabolic networks enables enzyme discovery. How much muscle strength is required to walk in a crouch gait? In-bore setup and software for 3T MRI-guided transperineal prostate biopsy. Calibration of multiple in silico tools for predicting pathogenicity of mismatch repair gene missense substitutions. Nanoinformatics: developing new computing applications for nanomedicine. Designing a public square for research computing.

Frontiers in growth and remodeling. Utilizing the integrated difference of two survival functions to quantify the treatment contrast for designing, monitoring, and analyzing a comparative clinical study. A gene expression profile of stem cell pluripotentiality and differentiation is conserved across diverse solid and hematopoietic cancers.

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A system to build distributed multivariate models and manage disparate data sharing policies: implementation in the scalable national network for effectiveness research. Convex Clustering with Exemplar-Based Models. Robust estimation of group-wise cortical correspondence with an application to macaque and human neuroimaging studies. Towards measuring neuroimage misalignment.

ABC transporters and the proteasome complex are implicated in susceptibility to Stevens-Johnson syndrome and toxic epidermal necrolysis across multiple drugs. The immunomodulatory effects of intravenous immunoglobulin therapy in Kawasaki disease. What Data to Co-register for Computing Atlases. A network of molecular switches controls the activation of the two-component response regulator NtrC. Contour-Driven Atlas-Based Segmentation.

Direct ChIP-Seq significance analysis improves target prediction. A diffusion tensor MRI atlas of the postmortem rhesus macaque brain. Affine Registration of label maps in Label Space. Shape index distribution based local surface complexity applied to the human cortex.

Annotating risk factors for heart disease in clinical narratives for diabetic patients. Building the graph of medicine from millions of clinical narratives. Federated queries of clinical data repositories: Scaling to a national network. Sharing my health data: a survey of data sharing preferences of healthy individuals. Trends in publication of nursing informatics research.

An information theoretic method to identify combinations of genomic alterations that promote glioblastoma. Altered corpus callosum morphology associated with autism over the first 2 years of life.

Bacterial division. Mechanical crack propagation drives millisecond daughter cell separation in Staphylococcus aureus. Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources. Genetic similarity between cancers and comorbid Mendelian diseases identifies candidate driver genes. The association between lower educational attainment and depression owing to shared genetic effects? Development of phenotype algorithms using electronic medical records and incorporating natural language processing.

Statistical inference for nanopore sequencing with a biased random walk model. OpenSim: a musculoskeletal modeling and simulation framework for in silico investigations and exchange.

BAP1 mutation is a frequent somatic event in peritoneal malignant mesothelioma. Identifying candidate drivers of alcohol dependence-induced excessive drinking by assembly and interrogation of brain-specific regulatory networks. Grid multi-category response logistic models. Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma.

Normalization of relative and incomplete temporal expressions in clinical narratives. Simbody: multibody dynamics for biomedical research. Diabetes and the risk of infections with immunomodulator therapy in inflammatory bowel diseases.

Neuroinformatics and the The Insight ToolKit. Role of TGF-? Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. Development of a web service for analysis in a distributed network.

Predictive simulation generates human adaptations during loaded and inclined walking. Comparison of consumers' views on electronic data sharing for healthcare and research. Variations in the binding pocket of an inhibitor of the bacterial division protein FtsZ across genotypes and species.

Ranking adverse drug reactions with crowdsourcing. Cardiovascular pathology in 2 young adults with sudden, unexpected death due to coronary aneurysms from Kawasaki disease in childhood. Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression. Quantitative modeling of transcription factor binding specificities using DNA shape.

Transient pairing of homologous Oct4 alleles accompanies the onset of embryonic stem cell differentiation. Running with a load increases leg stiffness. Patient-specific biomechanical model as whole-body CT image registration tool. Gene-wide identification of episodic selection. Less is more: an adaptive branch-site random effects model for efficient detection of episodic diversifying selection. Template-based prediction of protein function.

Gene interactions and structural brain change in early-onset Alzheimer's disease subjects using the pipeline environment. Geodesic image regression with a sparse parameterization of diffeomorphisms. Geometric Science of Information 1st : : Paris, France.

Identification of rare germline copy number variations over-represented in five human cancer types. A time-indexed reference standard of adverse drug reactions. Comparing 3T and 1. BrainPrint: a discriminative characterization of brain morphology.

Cloud computing approaches for prediction of ligand binding poses and pathways. Analyzing search behavior of healthcare professionals for drug safety surveillance.

Single-molecule dataset SMD : a generalized storage format for raw and processed single-molecule data. Overcome support vector machine diagnosis overfitting. A novel genome-wide significant locus on chromosome 2 near ASB3. Medial frontal white and gray matter contributions to general intelligence. Epileptogenic focus localization in treatment-resistant post-traumatic epilepsy. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia.

RELAX: detecting relaxed selection in a phylogenetic framework. Genotype to phenotype relationships in autism spectrum disorders. Scalable privacy-preserving data sharing methodology for genome-wide association studies: an application to iDASH healthcare privacy protection challenge. Differentially private genome data dissemination through top-down specialization. A community assessment of privacy preserving techniques for human genomes.

Longitudinal quantification and visualization of intracerebral haemorrhage using multimodal magnetic resonance and diffusion tensor imaging. Segmentation of cerebrovascular pathologies in stroke patients with spatial and shape priors.

Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia. Is my model good enough? Best practices for verification and validation of musculoskeletal models and simulations of movement.

Multi-modal robust inverse-consistent linear registration. Differences in muscle activity between natural forefoot and rearfoot strikers during running. Integration of genomic data enables selective discovery of breast cancer drivers.

Comment on: ''Zoo or savannah? Choice of training ground for evidence-based pharmacovigilance''. Multimodal neuroimaging feature learning for multiclass diagnosis of Alzheimer's disease. A community computational challenge to predict the activity of pairs of compounds. Discovering chemistry with an ab initio nanoreactor.

Text mining in cancer gene and pathway prioritization. Statistical estimation of physiological brain age as a descriptor of senescence rate during adulthood. Long-term phenotypic evolution of bacteria. The genetic basis of chronic mountain sickness. ArrayExpress update--simplifying data submissions. Choosing blindly but wisely: differentially private solicitation of DNA datasets for disease marker discovery.

Disease Ontology update: an expanded and updated database of human diseases for linking biomedical knowledge through disease data. Automatic identification of methotrexate-induced liver toxicity in patients with rheumatoid arthritis from the electronic medical record.

Computational modeling of hypertensive growth in the human carotid artery. Systems biology. Conditional density-based analysis of T cell signaling in single-cell data. The DTI connectivity of the human claustrum. Functional evaluation of out-of-the-box text-mining tools for data-mining tasks.

Interrogation of a context-specific transcription factor network identifies novel regulators of pluripotency. Atlas-based under-segmentation. Gaussian process interpolation for uncertainty estimation in image registration. Diffeomorphic shape trajectories for improved longitudinal segmentation and statistics. BrainPrint: identifying subjects by their brain. Subject-specific prediction using nonlinear population modeling: application to early brain maturation from DTI.

Hierarchical bayesian modeling, estimation, and sampling for multigroup shape analysis. Evolving insights on how cytosine methylation affects protein-DNA binding. Inferring protein modulation from gene expression data using conditional mutual information.

Cingulum bundle integrity associated with delusions of control in schizophrenia: Preliminary evidence from diffusion-tensor tractography. Characterizing growth patterns in longitudinal MRI using image contrast. Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks.

International Conference on Machine Learning. Predicting accurate probabilities with a ranking loss. Machine learning : proceedings of the International Conference. Abstractions for Genomics.

The Living Heart Project: A robust and integrative simulator for human heart function. Multivariate longitudinal shape analysis of human lateral ventricles during the first twenty-four months of life. IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform.

Computational modeling of skin: Using stress profiles as predictor for tissue necrosis in reconstructive surgery. Mode of childbirth and long-term outcomes in women with inflammatory bowel diseases. Co-regulated transcripts associated to cooperating eSNPs define Bi-fan motifs in human gene networks.

Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins. The role of mechanics during brain development. Use it or lose it: multiscale skeletal muscle adaptation to mechanical stimuli. Sparse kernel machine regression for ordinal outcomes. Pegasus: a comprehensive annotation and prediction tool for detection of driver gene fusions in cancer.

Decoupling function and anatomy in atlases of functional connectivity patterns: language mapping in tumor patients. Comparative analysis of metazoan chromatin organization. In search of the determinants of enhancer-promoter interaction specificity. Prenatal antidepressant exposure is associated with risk for attention-deficit hyperactivity disorder but not autism spectrum disorder in a large health system.

SELEX-seq: a method for characterizing the complete repertoire of binding site preferences for transcription factor complexes. Complex pathways in folding of protein G explored by simulation and experiment. Evolution of the central sulcus morphology in primates. Treatment selections using risk-benefit profiles based on data from comparative randomized clinical trials with multiple endpoints.

Multiple LacI-mediated loops revealed by Bayesian statistics and tethered particle motion. Classification of CT pulmonary angiography reports by presence, chronicity, and location of pulmonary embolism with natural language processing. Differentially private distributed logistic regression using private and public data.

Data-driven discovery of seasonally linked diseases from an Electronic Health Records system. Multi-atlas segmentation with particle-based group-wise image registration. Impact of family history on prostate cancer mortality in white men undergoing prostate specific antigen based screening. Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records.

Lipoprotein particle concentrations in children and adults following Kawasaki disease. An autism case history to review the systematic analysis of large-scale data to refine the diagnosis and treatment of neuropsychiatric disorders. Robust Radiomics feature quantification using semiautomatic volumetric segmentation. Characterization of living skin using multi-view stereo and isogeometric analysis.

Privacy preserving RBF kernel support vector machine. A mechanical model predicts morphological abnormalities in the developing human brain. Localized abnormalities in the cingulum bundle in patients with schizophrenia: a Diffusion Tensor tractography study. Prenatal cocaine effects on brain structure in early infancy. Toward personalizing treatment for depression: predicting diagnosis and severity. ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2. Morphometry of anatomical shape complexes with dense deformations and sparse parameters.

Characterizing a collective and dynamic component of chromatin immunoprecipitation enrichment profiles in yeast. The elusive evidence for chromothripsis. Harnessing natural sequence variation to dissect posttranscriptional regulatory networks in yeast.

Multi-Channel neurodegenerative pattern analysis and its application in Alzheimer's disease characterization. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society.

Inferring gene ontologies from pairwise similarity data. Dysmorphogenic effects of first trimester-equivalent ethanol exposure in mice: a magnetic resonance microscopy-based study. Fluoroquinolone resistant rectal colonization predicts risk of infectious complications after transrectal prostate biopsy. Integrative biology identifies shared transcriptional networks in CKD.

OpenIGTLink interface for state control and visualisation of a robot for image-guided therapy systems. MAGI: a Node. Structural bioinformatics of the interactome. A community effort to assess and improve drug sensitivity prediction algorithms. Natural language processing in biomedicine: a unified system architecture overview. Evaluating the effects of machine pre-annotation and an interactive annotation interface on manual de-identification of clinical text.

Transfer learning based clinical concept extraction on data from multiple sources. Structural and connectomic neuroimaging for the personalized study of longitudinal alterations in cortical shape, thickness and connectivity after traumatic brain injury.

Meshless Modeling of Deformable Shapes and their Motion. Patient-level temporal aggregation for text-based asthma status ascertainment. Efficient inverse isoparametric mapping algorithm for whole-body computed tomography registration using deformations predicted by nonlinear finite element modeling.

Response of Escherichia coli growth rate to osmotic shock. A graph algebra for scalable visual analytics. Multiatlas segmentation as nonparametric regression. Coping with confounds in multivoxel pattern analysis: what should we do about reaction time differences? Automatic segmentation of head and neck CT images for radiotherapy treatment planning using multiple atlases, statistical appearance models, and geodesic active contours. Evaluating marker-guided treatment selection strategies.

Variations of dynamic contrast-enhanced magnetic resonance imaging in evaluation of breast cancer therapy response: a multicenter data analysis challenge. Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development.

Knowledge-based fragment binding prediction. A complete system for automatic extraction of left ventricular myocardium from CT images using shape segmentation and contour evolution.

Ensuring privacy in the study of pathogen genetics. Mutual information as a measure of image quality for 3D dynamic lung imaging with EIT.

Identifying regulatory mechanisms underlying tumorigenesis using locus expression signature analysis. Response to letters regarding article, "unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine". Population-level evidence for an autoimmune etiology of epilepsy. Joint modeling of imaging and genetics. Geodesic shape regression in the framework of currents. Bayesian segmentation of atrium wall using globally-optimal graph cuts on 3D meshes.

Group-wise cortical correspondence via sulcal curve-constrained entropy minimization. Sparse projections of medical images onto manifolds. A longitudinal functional analysis framework for analysis of white matter tract statistics. Aldosterone dysregulation with aging predicts renal vascular function and cardiovascular risk. Bayesian energy landscape tilting: towards concordant models of molecular ensembles.

Empirical Bayes methods enable advanced population-level analyses of single-molecule FRET experiments. Developing image processing meta-algorithms with data mining of multiple metrics. Cerebral white matter abnormalities and their associations with negative but not positive symptoms of schizophrenia. Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases. Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma.

High precision prediction of functional sites in protein structures. MAAMD: a workflow to standardize meta-analyses and comparison of affymetrix microarray data.

Neuroinformatics challenges to the structural, connectomic, functional and electrophysiological multimodal imaging of human traumatic brain injury. Changes in tibiofemoral forces due to variations in muscle activity during walking. Pregnancy in women with a history of Kawasaki disease: management and outcomes.

Semantics in support of biodiversity knowledge discovery: an introduction to the biological collections ontology and related ontologies. The automated function prediction SIG looks back at and prepares for Automated detection of off-label drug use. Multifold Bayesian kernelization in Alzheimer's diagnosis. Geodesic distances to landmarks for dense correspondence on ensembles of complex shapes. Systematic network lesioning reveals the core white matter scaffold of the human brain.

Multi-atlas segmentation of subcortical brain structures via the AutoSeg software pipeline. SAVI: a statistical algorithm for variant frequency identification. On the mechanics of growing thin biological membranes.

Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease. Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes.

When you can't tell when it hurts: a preliminary algorithm to assess pain in patients who can't communicate. Crowdsourcing the verification of relationships in biomedical ontologies.

Building and evaluating an ontology-based tool for reasoning about consent permission. Effects of polymerization and nucleotide identity on the conformational dynamics of the bacterial actin homolog MreB.

Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness. Annotating the structure and components of a nanoparticle formulation using computable string expressions.

Rare copy number variation in treatment-resistant major depressive disorder. DTIPrep: quality control of diffusion-weighted images. Semi-Automatic Parcellation of the Corpus Striatum. Validation of catheter segmentation for MR-guided gynecologic cancer brachytherapy. Contour-driven regression for label inference in atlas-based segmentation.

Particle-guided image registration. Detecting epileptic regions based on global brain connectivity patterns. Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia. Specificity of regulatory T cells that modulate vascular inflammation. Differential privacy based on importance weighting.

Web-based tools for modelling and analysis of multivariate data: California ozone pollution activity. More accurate neuronavigation data provided by biomechanical modeling instead of rigid registration. MutPred Splice: machine learning-based prediction of exonic variants that disrupt splicing. Word sense disambiguation in the clinical domain: a comparison of knowledge-rich and knowledge-poor unsupervised methods.

Automatic lymphoma classification with sentence subgraph mining from pathology reports. Regional neuroplastic brain changes in patients with chronic inflammatory and non-inflammatory visceral pain. A midas plugin to enable construction of reproducible web-based image processing pipelines.

Serum inflammatory markers and risk of colorectal cancer in patients with inflammatory bowel diseases. A framework for longitudinal data analysis via shape regression.

Fast approximate surface evolution in arbitrary dimension. Studying PubMed usages in the field for complex problem solving: Implications for tool design. Atrial fibrillation ablation outcome is predicted by left atrial remodeling on MRI. Stochastic Image Registration with User Constraints. Fiber feature map based landmark initialization for highly deformable DTI registration. Quality Control of Diffusion Weighted Images. The environment ontology: contextualising biological and biomedical entities.

Omnibus risk assessment via accelerated failure time kernel machine modeling. Treatment response in kawasaki disease is associated with sialylation levels of endogenous but not therapeutic intravenous immunoglobulin G. Comorbidity clusters in autism spectrum disorders: an electronic health record time-series analysis. Mining the ultimate phenome repository. The neurological disease ontology. Discussion of ''Biomedical informatics: we are what we publish''.

Amplification and thrifty single-molecule sequencing of recurrent somatic structural variations. Genome-wide DNA methylation changes with age in disease free human skeletal muscle.

Calculations of the electric fields in liquid solutions. Learning signals of adverse drug-drug interactions from the unstructured text of electronic health records. Network analysis of unstructured EHR data for clinical research.

Profiling risk factors for chronic uveitis in juvenile idiopathic arthritis: a new model for EHR-based research. Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. Associations of smoking and alcohol consumption with disease activity and functional status in rheumatoid arthritis. Predicting the restricted mean event time with the subject's baseline covariates in survival analysis.

Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia. Genetic robustness and functional evolution of gene duplicates. Three-dimensional treatment outcomes in Class II patients treated with the Herbst appliance: a pilot study. Chronology of your health events: approaches to extracting temporal relations from medical narratives.

OnTheFly: a database of Drosophila melanogaster transcription factors and their binding sites. SGPP: spatial Gaussian predictive process models for neuroimaging data. State of the human proteome in as viewed through PeptideAtlas: comparing the kidney, urine, and plasma proteomes for the biology- and disease-driven Human Proteome Project.

Reviewing the ketamine model for schizophrenia. Modeling disease severity in multiple sclerosis using electronic health records. Growing matter: a review of growth in living systems. Predictors of plasma and urinary catecholamine levels in normotensive and hypertensive men and women. Towards generating a patient's timeline: extracting temporal relationships from clinical notes. Improved segmentation of white matter tracts with adaptive Riemannian metrics.

In silico approaches and the role of ontologies in aging research. Using search queries for malaria surveillance, Thailand. Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome. Three-dimensional analysis of maxillary changes associated with facemask and rapid maxillary expansion compared with bone anchored maxillary protraction.

Neuroimaging of structural pathology and connectomics in traumatic brain injury: Toward personalized outcome prediction. Topology of viral evolution. Regional 3D superimposition to assess temporomandibular joint condylar morphology. Leveraging electronic health records to notify pediatric patients of a drug recall. Mining clinical text for signals of adverse drug-drug interactions. Application of universal stress proteins in probing the dynamics of potent degraders in complex terephthalate metagenome.

Automated chart review for asthma cohort identification using natural language processing: an exploratory study. Nocturnal continuous glucose and sleep stage data in adults with type 1 diabetes in real-world conditions. Human neuroimaging as a "Big Data" science. Distinct splice variants and pathway enrichment in the cell-line models of aggressive human breast cancer subtypes.

Localized Sparse Code Gradient in Alzheimer's disease staging. Conference proceedings Annual Conference. Nucleotide sequence alignment using sparse coding and belief propagation. Discovering body site and severity modifiers in clinical texts. Improved de-identification of physician notes through integrative modeling of both public and private medical text.

Temporal relation discovery between events and temporal expressions identified in clinical narrative. FMEM: functional mixed effects modeling for the analysis of longitudinal white matter Tract data. A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk.

Neural encoding of acupuncture needling sensations: evidence from a FMRI study. Seasonality of Kawasaki disease: a global perspective. Instrumentation bias in the use and evaluation of scientific software: recommendations for reproducible practices in the computational sciences.

Automatic segmentation of the left atrium from MR images via variational region growing with a moments-based shape prior. Combining an expert-based medical entity recognizer to a machine-learning system: methods and a case study.

Opportunities for genomic clinical decision support interventions. A novel strategy to identify the critical conditions for growth-induced instabilities.

Temporomandibular joint condylar changes following maxillomandibular advancement and articular disc repositioning. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. Sex-related differences of cortical thickness in patients with chronic abdominal pain.

On the design of clone-based haplotyping. A molecular signature predictive of indolent prostate cancer. Extraction of events and temporal expressions from clinical narratives. Tissue-specific profiling reveals transcriptome alterations in Arabidopsis mutants lacking morphological phenotypes.

Assessment of biomarkers for risk prediction with nested case-control studies. Electroencephalographic inverse localization of brain activity in acute traumatic brain injury as a guide to surgery, monitoring and treatment. A new tool for sharing and querying of clinical documents modeled using HL7 Version 3 standard. Prostate cancer detection and diagnosis: the role of MR and its comparison with other diagnostic modalities--a radiologist's perspective.

Automated skin segmentation in ultrasonic evaluation of skin toxicity in breast cancer radiotherapy. Using twitter to examine smoking behavior and perceptions of emerging tobacco products. PhenDisco: phenotype discovery system for the database of genotypes and phenotypes. Virmid: accurate detection of somatic mutations with sample impurity inference.

Identification of Functional Regulatory Residues of the? Automatic prediction of rheumatoid arthritis disease activity from the electronic medical records. On the effect of prestrain and residual stress in thin biological membranes.

Multimodal deformable registration of traumatic brain injury MR volumes via the Bhattacharyya distance. Toward a comprehensive framework for the spatiotemporal statistical analysis of longitudinal shape data.

Identifying phenotypic signatures of neuropsychiatric disorders from electronic medical records. Classifying temporal relations in clinical data: A hybrid, knowledge-rich approach.

Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders. Mapping cortical atrophy in Parkinson's disease patients with dementia. Lipid and lipoprotein levels and trend in rheumatoid arthritis compared to the general population. Extending the NegEx lexicon for multiple languages. ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer.

The integrated landscape of driver genomic alterations in glioblastoma. Shape abnormalities of the caudate nucleus correlate with poorer gait and balance: results from a subset of the LADIS study. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Magnetic resonance microscopy-based analyses of the neuroanatomical effects of gestational day 9 ethanol exposure in mice. MedTime: a temporal information extraction system for clinical narratives. Syntactic parsing of clinical text: guideline and corpus development with handling ill-formed sentences.

Immune-monitoring in Kawasaki disease patients treated with infliximab and intravenous immunoglobulin. A locally adaptive regularization based on anisotropic diffusion for deformable image registration of sliding organs. Interactive medical image segmentation using PDE control of active contours. Localizing the human primary auditory cortex in vivo using structural MRI. Fast local trust region technique for diffusion tensor registration using exact reorientation and regularization.

Annotating temporal information in clinical narratives. Semantator: Semantic annotator for converting biomedical text to linked data. From connectivity models to region labels: identifying foci of a neurological disorder. Computational semantics in clinical text.

Longitudinal image registration with temporally-dependent image similarity measure. Variants in exons and in transcription factors affect gene expression in trans. Ground state destabilization by anionic nucleophiles contributes to the activity of phosphoryl transfer enzymes. Statistical shape modeling of cam femoroacetabular impingement. Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine.

Sarcomere lengths in human extensor carpi radialis brevis measured by microendoscopy. Inference of historical migration rates via haplotype sharing. Improving data and knowledge management to better integrate health care and research. Adopting nested case-control quota sampling designs for the evaluation of risk markers. Decreased axial diffusivity within language connections: A possible biomarker of schizophrenia risk. Sparse texture active contour.

Computational modeling of chemo-electro-mechanical coupling: a novel implicit monolithic finite element approach. Increased gray matter diffusion anisotropy in patients with persistent post-concussive symptoms following mild traumatic brain injury. Privacy technology to support data sharing for comparative effectiveness research: a systematic review.

Long-term 3-dimensional stability of mandibular advancement surgery. Using Genome Query Language to uncover genetic variation. Systematic improvement of a classical molecular model of water.

Mechanical consequences of cell-wall turnover in the elongation of a Gram-positive bacterium. Forward and inverse electroencephalographic modeling in health and in acute traumatic brain injury.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. Automatic delineation of the myocardial wall from CT images via shape segmentation and variational region growing.

Hypothalamic proteoglycan syndecan-3 is a novel cocaine addiction resilience factor. Evaluating genome architecture of a complex region via generalized bipartite matching. Extracting physician group intelligence from electronic health records to support evidence based medicine. Dynamic Active Contours for Visual Tracking.

Spatial-temporal atlas of human fetal brain development during the early second trimester. Practice-based evidence: profiling the safety of cilostazol by text-mining of clinical notes.

Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls. A rolling constraint reproduces ground reaction forces and moments in dynamic simulations of walking, running, and crouch gait.

Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway. Inferences on the biochemical and environmental regulation of universal stress proteins from Schistosomiasis parasites. Impact of sex and gonadal steroids on neonatal brain structure. Morse-Smale Regression. Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America.

A flexible framework for recognizing events, temporal expressions, and temporal relations in clinical text. Human middle longitudinal fascicle: segregation and behavioral-clinical implications of two distinct fiber connections linking temporal pole and superior temporal gyrus with the angular gyrus or superior parietal lobule using multi-tensor tractography.

Diffusion imaging quality control via entropy of principal direction distribution. Temporal reasoning over clinical text: the state of the art. Beyond NPM-anaplastic lymphoma kinase driven lymphomagenesis: alternative drivers in anaplastic large cell lymphoma.

Improving breast cancer survival analysis through competition-based multidimensional modeling. Reprever: resolving low-copy duplicated sequences using template driven assembly. HIV infection reveals widespread expansion of novel centromeric human endogenous retroviruses.

Surgery, virtual reality, and the future. Enhanced modeling via network theory: Adaptive sampling of Markov state models. Growth on demand: Reviewing the mechanobiology of stretched skin.

Optical flow estimation for flame detection in videos. Genetic contributions to changes of fiber tracts of ventral visual stream in 22q Lateral ventricle morphology analysis via mean latitude axis. On the mechanics of continua with boundary energies and growing surfaces. Combining rules and machine learning for extraction of temporal expressions and events from clinical narratives.

Heterogeneity of tumor-induced gene expression changes in the human metabolic network. Innovations in proteomic profiling of cancers: alternative splice variants as a new class of cancer biomarker candidates and bridging of proteomics with structural biology. Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer.

Dominant effects of the Huntington's disease HTT CAG repeat length are captured in gene-expression data sets by a continuous analysis mathematical modeling strategy. Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver.

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Towards improved ultrasound-based analysis and 3D visualization of the fetal brain using the 3D Slicer. Eventual situations for timeline extraction from clinical reports. A hybrid system for temporal information extraction from clinical text.

Pharmacovigilance using clinical notes. Performance of pharmacovigilance signal-detection algorithms for the FDA adverse event reporting system. Diffusion weighted imaging of prefrontal cortex in prodromal huntington's disease. Evaluating temporal relations in clinical text: i2b2 Challenge. A controlled greedy supervised approach for co-reference resolution on clinical text. Comprehensive temporal information detection from clinical text: medical events, time, and TLINK identification.

Natural Language Processing to identify pneumonia from radiology reports. The stationary configuration of the knee. MutComFocal: an integrative approach to identifying recurrent and focal genomic alterations in tumor samples. An informational framework to predict reaction of constraints using a reciprocally connected knee model. An algorithmic approach for breakage-fusion-bridge detection in tumor genomes.

Six-week gait retraining program reduces knee adduction moment, reduces pain, and improves function for individuals with medial compartment knee osteoarthritis. Landmark risk prediction of residual life for breast cancer survival. Differential expression of miR in children with Kawasaki disease. How muscle fiber lengths and velocities affect muscle force generation as humans walk and run at different speeds. An end-to-end system to identify temporal relation in discharge summaries: i2b2 challenge.

Web-scale pharmacovigilance: listening to signals from the crowd. Automating the study of population variation of electrocardiographic features. Referent tracking for treatment optimisation in schizophrenic patients: A case study in applying philosophical ontology to diagnostic algorithms.

Stretching skin: The physiological limit and beyond. GBM volumetry using the 3D Slicer medical image computing platform. Flexing computational muscle: modeling and simulation of musculotendon dynamics. Comparison of four prediction models to discriminate benign from malignant vertebral compression fractures according to MRI feature analysis. From single nucleotide polymorphism to transcriptional mechanism: a model for FRMD3 in diabetic nephropathy.

MetaSeq: privacy preserving meta-analysis of sequencing-based association studies. Insights into diseases of human telomerase from dynamical modeling. Molecular dynamics simulations for the ranking, evaluation, and refinement of computationally designed proteins.

Wessim: a whole-exome sequencing simulator based on in silico exome capture. N-glycoproteome of E Tg2a mouse embryonic stem cells. One-year assessment of surgical outcomes in Class III patients using cone beam computed tomography. Abnormal aldosterone physiology and cardiometabolic risk factors. Classic "broken cell" techniques and newer live cell methods for cell cycle assessment. Properties of cell death models calibrated and compared using Bayesian approaches.

Detecting concept relations in clinical text: insights from a state-of-the-art model. Recursive feature elimination for brain tumor classification using desorption electrospray ionization mass spectrometry imaging. Automatic segmentation of the left atrium from MRI images using salient feature and contour evolution. Quantifying pathogen surveillance using temporal genomic data. QT interval and antidepressant use: a cross sectional study of electronic health records.

Gene expression alterations in bipolar disorder postmortem brains. Multiscale adaptive generalized estimating equations for longitudinal neuroimaging data. Evaluation of methods for modeling transcription factor sequence specificity. A large-scale evaluation of computational protein function prediction. Federated queries of clinical data repositories: the sum of the parts does not equal the whole.

White matter fractional anisotropy is inversely related to anxious symptoms in older adults with atherosclerosis. Similar risk of depression and anxiety following surgery or hospitalization for Crohn's disease and ulcerative colitis. Exact statistical tests for the intersection of independent lists of genes. Systems-based approaches toward wound healing. Sexually dimorphic white matter geometry abnormalities in adolescent onset schizophrenia.

Selecting cases for whom additional tests can improve prognostication. Towards mechanism classifiers: expression-anchored Gene Ontology signature predicts clinical outcome in lung adenocarcinoma patients. Towards the creation of a visual ontology of biomedical imaging entities. The relationship between structural characteristics of challenge documents and ratings of document quality.

Applications of ontology design patterns in biomedical ontologies. A semi-automated quantification of pulmonary artery dimensions in computed tomography angiography images. Chapter 9: Analyses using disease ontologies.

Abnormalities of middle longitudinal fascicle and disorganization in patients with schizophrenia. Psychiatric co-morbidity is associated with increased risk of surgery in Crohn's disease. Learning a reliable estimate of the number of fiber directions in diffusion MRI. Spectral label fusion. Longitudinal image registration with non-uniform appearance change. Topology preserving atlas construction from shape data without correspondence using sparse parameters. Metamorphic geodesic regression.

Group analysis of resting-state fMRI by hierarchical Markov random fields. A feature-based developmental model of the infant brain in structural MRI. Fast diffusion tensor registration with exact reorientation and regularization. Analytic regularization of uniform cubic B-spline deformation fields. Analysis of longitudinal shape variability via subject specific growth modeling.

From brain connectivity models to identifying foci of a neurological disorder. Common variants in psychiatric risk genes predict brain structure at birth. MicroRNA-centric measurement improves functional enrichment analysis of co-expressed and differentially expressed microRNA clusters. Regionally selective atrophy of subcortical structures in prodromal HD as revealed by statistical shape analysis. OntoMaton: a bioportal powered ontology widget for Google Spreadsheets. The variance of identity-by-descent sharing in the Wright-Fisher model.

Subgroup specific incremental value of new markers for risk prediction. Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis.

A chromosome-centric human proteome project C-HPP to characterize the sets of proteins encoded in chromosome Tissue plasminogen activator prevents mortality from sulfur mustard analog-induced airway obstruction.

Fiber tractography based on diffusion tensor imaging compared with high-angular-resolution diffusion imaging with compressed sensing: initial experience. Evaluating incremental values from new predictors with net reclassification improvement in survival analysis. To share or not to share: that is not the question. Muscle contributions to fore-aft and vertical body mass center accelerations over a range of running speeds.

Sharing data for the public good and protecting individual privacy: informatics solutions to combine different goals. Privacy-preserving heterogeneous health data sharing. Pituitary adenoma volumetry with 3D Slicer. To milliseconds and beyond: challenges in the simulation of protein folding.

Regional characterization of longitudinal DT-MRI to study white matter maturation of the early developing brain. Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls.

The plant ontology as a tool for comparative plant anatomy and genomic analyses. Generating fibre orientation maps in human heart models using Poisson interpolation. Ontology-based combinatorial comparative analysis of adverse events associated with killed and live influenza vaccines.

Muscle contributions to vertical and fore-aft accelerations are altered in subjects with crouch gait. ArrayExpress update--trends in database growth and links to data analysis tools. PrePPI: a structure-informed database of protein-protein interactions.

So this week, our friends at Throughline are helping us understand the fuller story. The cover of Bethany C. Morrow's new book, So Many Beginnings. Jonathan Barkat hide caption. Trump supporters try to break through a police barrier Jan. Capitol in Washington, D. It's a powerful term that's had lasting implications for communities around the world. Alexis Nikole Nelson is behind the popular TikTok and Instagram videos based on her experience and advice on foraging.

Her mission: to report on a meeting of thousands of organizers and ambassadors gathered at a global conference on racism. The conference filled Shereen with hope and optimism — all of which would soon be wiped away.

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Is it better to explain every reference, or ask people to Google as they go? Comedian Hari Kondabolu joins us to hash it out. But there is so much police violence that falls short of being fatal, but forever alters the lives of the people on the business end of it.

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Soundcore Liberty 3 pro TWS earbuds. The Tablet Den Share and discuss everything related to the growing popularity of tablet devices here, from iPads to the many Android tablets! This is the one stop place for you tablet lovers! Sub-forums: The iPad Sanctum.

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Yesterday at PM Ottoke. Others Others.. Relate your experiences with others. Threads Messages 7. Evolution of the central sulcus morphology in primates. Treatment selections using risk-benefit profiles based on data from comparative randomized clinical trials with multiple endpoints. Multiple LacI-mediated loops revealed by Bayesian statistics and tethered particle motion.

Classification of CT pulmonary angiography reports by presence, chronicity, and location of pulmonary embolism with natural language processing. Differentially private distributed logistic regression using private and public data.

Data-driven discovery of seasonally linked diseases from an Electronic Health Records system. Multi-atlas segmentation with particle-based group-wise image registration. Impact of family history on prostate cancer mortality in white men undergoing prostate specific antigen based screening.

Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records. Lipoprotein particle concentrations in children and adults following Kawasaki disease. An autism case history to review the systematic analysis of large-scale data to refine the diagnosis and treatment of neuropsychiatric disorders.

Robust Radiomics feature quantification using semiautomatic volumetric segmentation. Characterization of living skin using multi-view stereo and isogeometric analysis. Privacy preserving RBF kernel support vector machine. A mechanical model predicts morphological abnormalities in the developing human brain. Localized abnormalities in the cingulum bundle in patients with schizophrenia: a Diffusion Tensor tractography study.

Prenatal cocaine effects on brain structure in early infancy. Toward personalizing treatment for depression: predicting diagnosis and severity. ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2. Morphometry of anatomical shape complexes with dense deformations and sparse parameters.

Characterizing a collective and dynamic component of chromatin immunoprecipitation enrichment profiles in yeast.

The elusive evidence for chromothripsis. Harnessing natural sequence variation to dissect posttranscriptional regulatory networks in yeast. Multi-Channel neurodegenerative pattern analysis and its application in Alzheimer's disease characterization. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. Inferring gene ontologies from pairwise similarity data. Dysmorphogenic effects of first trimester-equivalent ethanol exposure in mice: a magnetic resonance microscopy-based study.

Fluoroquinolone resistant rectal colonization predicts risk of infectious complications after transrectal prostate biopsy. Integrative biology identifies shared transcriptional networks in CKD. OpenIGTLink interface for state control and visualisation of a robot for image-guided therapy systems. MAGI: a Node. Structural bioinformatics of the interactome.

A community effort to assess and improve drug sensitivity prediction algorithms. Natural language processing in biomedicine: a unified system architecture overview. Evaluating the effects of machine pre-annotation and an interactive annotation interface on manual de-identification of clinical text.

Transfer learning based clinical concept extraction on data from multiple sources. Structural and connectomic neuroimaging for the personalized study of longitudinal alterations in cortical shape, thickness and connectivity after traumatic brain injury.

Meshless Modeling of Deformable Shapes and their Motion. Patient-level temporal aggregation for text-based asthma status ascertainment.

Efficient inverse isoparametric mapping algorithm for whole-body computed tomography registration using deformations predicted by nonlinear finite element modeling. Response of Escherichia coli growth rate to osmotic shock. A graph algebra for scalable visual analytics. Multiatlas segmentation as nonparametric regression. Coping with confounds in multivoxel pattern analysis: what should we do about reaction time differences? Automatic segmentation of head and neck CT images for radiotherapy treatment planning using multiple atlases, statistical appearance models, and geodesic active contours.

Evaluating marker-guided treatment selection strategies. Variations of dynamic contrast-enhanced magnetic resonance imaging in evaluation of breast cancer therapy response: a multicenter data analysis challenge.

Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development. Knowledge-based fragment binding prediction. A complete system for automatic extraction of left ventricular myocardium from CT images using shape segmentation and contour evolution. Ensuring privacy in the study of pathogen genetics. Mutual information as a measure of image quality for 3D dynamic lung imaging with EIT. Identifying regulatory mechanisms underlying tumorigenesis using locus expression signature analysis.

Response to letters regarding article, "unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine". Population-level evidence for an autoimmune etiology of epilepsy.

Joint modeling of imaging and genetics. Geodesic shape regression in the framework of currents. Bayesian segmentation of atrium wall using globally-optimal graph cuts on 3D meshes. Group-wise cortical correspondence via sulcal curve-constrained entropy minimization. Sparse projections of medical images onto manifolds.

A longitudinal functional analysis framework for analysis of white matter tract statistics. Aldosterone dysregulation with aging predicts renal vascular function and cardiovascular risk. Bayesian energy landscape tilting: towards concordant models of molecular ensembles. Empirical Bayes methods enable advanced population-level analyses of single-molecule FRET experiments. Developing image processing meta-algorithms with data mining of multiple metrics. Cerebral white matter abnormalities and their associations with negative but not positive symptoms of schizophrenia.

Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases. Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma. High precision prediction of functional sites in protein structures. MAAMD: a workflow to standardize meta-analyses and comparison of affymetrix microarray data. Neuroinformatics challenges to the structural, connectomic, functional and electrophysiological multimodal imaging of human traumatic brain injury.

Changes in tibiofemoral forces due to variations in muscle activity during walking. Pregnancy in women with a history of Kawasaki disease: management and outcomes. Semantics in support of biodiversity knowledge discovery: an introduction to the biological collections ontology and related ontologies.

The automated function prediction SIG looks back at and prepares for Automated detection of off-label drug use. Multifold Bayesian kernelization in Alzheimer's diagnosis. Geodesic distances to landmarks for dense correspondence on ensembles of complex shapes.

Systematic network lesioning reveals the core white matter scaffold of the human brain. Multi-atlas segmentation of subcortical brain structures via the AutoSeg software pipeline. SAVI: a statistical algorithm for variant frequency identification. On the mechanics of growing thin biological membranes. Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease. Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes.

When you can't tell when it hurts: a preliminary algorithm to assess pain in patients who can't communicate. Crowdsourcing the verification of relationships in biomedical ontologies. Building and evaluating an ontology-based tool for reasoning about consent permission.

Effects of polymerization and nucleotide identity on the conformational dynamics of the bacterial actin homolog MreB. Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness. Annotating the structure and components of a nanoparticle formulation using computable string expressions.

Rare copy number variation in treatment-resistant major depressive disorder. DTIPrep: quality control of diffusion-weighted images. Semi-Automatic Parcellation of the Corpus Striatum. Validation of catheter segmentation for MR-guided gynecologic cancer brachytherapy. Contour-driven regression for label inference in atlas-based segmentation.

Particle-guided image registration. Detecting epileptic regions based on global brain connectivity patterns. Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia.

Specificity of regulatory T cells that modulate vascular inflammation. Differential privacy based on importance weighting. Web-based tools for modelling and analysis of multivariate data: California ozone pollution activity.

More accurate neuronavigation data provided by biomechanical modeling instead of rigid registration. MutPred Splice: machine learning-based prediction of exonic variants that disrupt splicing. Word sense disambiguation in the clinical domain: a comparison of knowledge-rich and knowledge-poor unsupervised methods. Automatic lymphoma classification with sentence subgraph mining from pathology reports. Regional neuroplastic brain changes in patients with chronic inflammatory and non-inflammatory visceral pain.

A midas plugin to enable construction of reproducible web-based image processing pipelines. Serum inflammatory markers and risk of colorectal cancer in patients with inflammatory bowel diseases. A framework for longitudinal data analysis via shape regression.

Fast approximate surface evolution in arbitrary dimension. Studying PubMed usages in the field for complex problem solving: Implications for tool design.

Atrial fibrillation ablation outcome is predicted by left atrial remodeling on MRI. Stochastic Image Registration with User Constraints.

Fiber feature map based landmark initialization for highly deformable DTI registration. Quality Control of Diffusion Weighted Images. The environment ontology: contextualising biological and biomedical entities. Omnibus risk assessment via accelerated failure time kernel machine modeling. Treatment response in kawasaki disease is associated with sialylation levels of endogenous but not therapeutic intravenous immunoglobulin G.

Comorbidity clusters in autism spectrum disorders: an electronic health record time-series analysis. Mining the ultimate phenome repository. The neurological disease ontology. Discussion of ''Biomedical informatics: we are what we publish''. Amplification and thrifty single-molecule sequencing of recurrent somatic structural variations.

Genome-wide DNA methylation changes with age in disease free human skeletal muscle. Calculations of the electric fields in liquid solutions. Learning signals of adverse drug-drug interactions from the unstructured text of electronic health records. Network analysis of unstructured EHR data for clinical research. Profiling risk factors for chronic uveitis in juvenile idiopathic arthritis: a new model for EHR-based research.

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. Associations of smoking and alcohol consumption with disease activity and functional status in rheumatoid arthritis. Predicting the restricted mean event time with the subject's baseline covariates in survival analysis. Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia. Genetic robustness and functional evolution of gene duplicates.

Three-dimensional treatment outcomes in Class II patients treated with the Herbst appliance: a pilot study. Chronology of your health events: approaches to extracting temporal relations from medical narratives.

OnTheFly: a database of Drosophila melanogaster transcription factors and their binding sites. SGPP: spatial Gaussian predictive process models for neuroimaging data.

State of the human proteome in as viewed through PeptideAtlas: comparing the kidney, urine, and plasma proteomes for the biology- and disease-driven Human Proteome Project.

Reviewing the ketamine model for schizophrenia. Modeling disease severity in multiple sclerosis using electronic health records. Growing matter: a review of growth in living systems. Predictors of plasma and urinary catecholamine levels in normotensive and hypertensive men and women. Towards generating a patient's timeline: extracting temporal relationships from clinical notes. Improved segmentation of white matter tracts with adaptive Riemannian metrics. In silico approaches and the role of ontologies in aging research.

Using search queries for malaria surveillance, Thailand. Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome. Three-dimensional analysis of maxillary changes associated with facemask and rapid maxillary expansion compared with bone anchored maxillary protraction. Neuroimaging of structural pathology and connectomics in traumatic brain injury: Toward personalized outcome prediction.

Topology of viral evolution. Regional 3D superimposition to assess temporomandibular joint condylar morphology. Leveraging electronic health records to notify pediatric patients of a drug recall. Mining clinical text for signals of adverse drug-drug interactions. Application of universal stress proteins in probing the dynamics of potent degraders in complex terephthalate metagenome. Automated chart review for asthma cohort identification using natural language processing: an exploratory study.

Nocturnal continuous glucose and sleep stage data in adults with type 1 diabetes in real-world conditions. Human neuroimaging as a "Big Data" science. Distinct splice variants and pathway enrichment in the cell-line models of aggressive human breast cancer subtypes. Localized Sparse Code Gradient in Alzheimer's disease staging. Conference proceedings Annual Conference. Nucleotide sequence alignment using sparse coding and belief propagation.

Discovering body site and severity modifiers in clinical texts. Improved de-identification of physician notes through integrative modeling of both public and private medical text. Temporal relation discovery between events and temporal expressions identified in clinical narrative. FMEM: functional mixed effects modeling for the analysis of longitudinal white matter Tract data.

A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk. Neural encoding of acupuncture needling sensations: evidence from a FMRI study.

Seasonality of Kawasaki disease: a global perspective. Instrumentation bias in the use and evaluation of scientific software: recommendations for reproducible practices in the computational sciences.

Automatic segmentation of the left atrium from MR images via variational region growing with a moments-based shape prior. Combining an expert-based medical entity recognizer to a machine-learning system: methods and a case study.

Opportunities for genomic clinical decision support interventions. A novel strategy to identify the critical conditions for growth-induced instabilities. Temporomandibular joint condylar changes following maxillomandibular advancement and articular disc repositioning. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. Sex-related differences of cortical thickness in patients with chronic abdominal pain.

On the design of clone-based haplotyping. A molecular signature predictive of indolent prostate cancer. Extraction of events and temporal expressions from clinical narratives. Tissue-specific profiling reveals transcriptome alterations in Arabidopsis mutants lacking morphological phenotypes.

Assessment of biomarkers for risk prediction with nested case-control studies. Electroencephalographic inverse localization of brain activity in acute traumatic brain injury as a guide to surgery, monitoring and treatment. A new tool for sharing and querying of clinical documents modeled using HL7 Version 3 standard.

Prostate cancer detection and diagnosis: the role of MR and its comparison with other diagnostic modalities--a radiologist's perspective. Automated skin segmentation in ultrasonic evaluation of skin toxicity in breast cancer radiotherapy. Using twitter to examine smoking behavior and perceptions of emerging tobacco products.

PhenDisco: phenotype discovery system for the database of genotypes and phenotypes. Virmid: accurate detection of somatic mutations with sample impurity inference. Identification of Functional Regulatory Residues of the? Automatic prediction of rheumatoid arthritis disease activity from the electronic medical records. On the effect of prestrain and residual stress in thin biological membranes. Multimodal deformable registration of traumatic brain injury MR volumes via the Bhattacharyya distance.

Toward a comprehensive framework for the spatiotemporal statistical analysis of longitudinal shape data. Identifying phenotypic signatures of neuropsychiatric disorders from electronic medical records. Classifying temporal relations in clinical data: A hybrid, knowledge-rich approach. Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders. Mapping cortical atrophy in Parkinson's disease patients with dementia. Lipid and lipoprotein levels and trend in rheumatoid arthritis compared to the general population.

Extending the NegEx lexicon for multiple languages. ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer. The integrated landscape of driver genomic alterations in glioblastoma. Shape abnormalities of the caudate nucleus correlate with poorer gait and balance: results from a subset of the LADIS study.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. Magnetic resonance microscopy-based analyses of the neuroanatomical effects of gestational day 9 ethanol exposure in mice.

MedTime: a temporal information extraction system for clinical narratives. Syntactic parsing of clinical text: guideline and corpus development with handling ill-formed sentences. Immune-monitoring in Kawasaki disease patients treated with infliximab and intravenous immunoglobulin. A locally adaptive regularization based on anisotropic diffusion for deformable image registration of sliding organs. Interactive medical image segmentation using PDE control of active contours.

Localizing the human primary auditory cortex in vivo using structural MRI. Fast local trust region technique for diffusion tensor registration using exact reorientation and regularization. Annotating temporal information in clinical narratives. Semantator: Semantic annotator for converting biomedical text to linked data.

From connectivity models to region labels: identifying foci of a neurological disorder. Computational semantics in clinical text. Longitudinal image registration with temporally-dependent image similarity measure. Variants in exons and in transcription factors affect gene expression in trans. Ground state destabilization by anionic nucleophiles contributes to the activity of phosphoryl transfer enzymes. Statistical shape modeling of cam femoroacetabular impingement.

Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine. Sarcomere lengths in human extensor carpi radialis brevis measured by microendoscopy. Inference of historical migration rates via haplotype sharing. Improving data and knowledge management to better integrate health care and research. Adopting nested case-control quota sampling designs for the evaluation of risk markers.

Decreased axial diffusivity within language connections: A possible biomarker of schizophrenia risk. Sparse texture active contour. Computational modeling of chemo-electro-mechanical coupling: a novel implicit monolithic finite element approach. Increased gray matter diffusion anisotropy in patients with persistent post-concussive symptoms following mild traumatic brain injury. Privacy technology to support data sharing for comparative effectiveness research: a systematic review.

Long-term 3-dimensional stability of mandibular advancement surgery. Using Genome Query Language to uncover genetic variation. Systematic improvement of a classical molecular model of water. Mechanical consequences of cell-wall turnover in the elongation of a Gram-positive bacterium. Forward and inverse electroencephalographic modeling in health and in acute traumatic brain injury. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology.

Automatic delineation of the myocardial wall from CT images via shape segmentation and variational region growing. Hypothalamic proteoglycan syndecan-3 is a novel cocaine addiction resilience factor.

Evaluating genome architecture of a complex region via generalized bipartite matching. Extracting physician group intelligence from electronic health records to support evidence based medicine.

Dynamic Active Contours for Visual Tracking. Spatial-temporal atlas of human fetal brain development during the early second trimester. Practice-based evidence: profiling the safety of cilostazol by text-mining of clinical notes. Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls.

A rolling constraint reproduces ground reaction forces and moments in dynamic simulations of walking, running, and crouch gait. Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway. Inferences on the biochemical and environmental regulation of universal stress proteins from Schistosomiasis parasites.

Impact of sex and gonadal steroids on neonatal brain structure. Morse-Smale Regression. Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America.

A flexible framework for recognizing events, temporal expressions, and temporal relations in clinical text. Human middle longitudinal fascicle: segregation and behavioral-clinical implications of two distinct fiber connections linking temporal pole and superior temporal gyrus with the angular gyrus or superior parietal lobule using multi-tensor tractography.

Diffusion imaging quality control via entropy of principal direction distribution. Temporal reasoning over clinical text: the state of the art. Beyond NPM-anaplastic lymphoma kinase driven lymphomagenesis: alternative drivers in anaplastic large cell lymphoma. Improving breast cancer survival analysis through competition-based multidimensional modeling.

Reprever: resolving low-copy duplicated sequences using template driven assembly. HIV infection reveals widespread expansion of novel centromeric human endogenous retroviruses.

Surgery, virtual reality, and the future. Enhanced modeling via network theory: Adaptive sampling of Markov state models. Growth on demand: Reviewing the mechanobiology of stretched skin. Optical flow estimation for flame detection in videos.

Genetic contributions to changes of fiber tracts of ventral visual stream in 22q Lateral ventricle morphology analysis via mean latitude axis. On the mechanics of continua with boundary energies and growing surfaces. Combining rules and machine learning for extraction of temporal expressions and events from clinical narratives. Heterogeneity of tumor-induced gene expression changes in the human metabolic network. Innovations in proteomic profiling of cancers: alternative splice variants as a new class of cancer biomarker candidates and bridging of proteomics with structural biology.

Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer. Dominant effects of the Huntington's disease HTT CAG repeat length are captured in gene-expression data sets by a continuous analysis mathematical modeling strategy.

Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver. Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Towards improved ultrasound-based analysis and 3D visualization of the fetal brain using the 3D Slicer.

Eventual situations for timeline extraction from clinical reports. A hybrid system for temporal information extraction from clinical text.

Pharmacovigilance using clinical notes. Performance of pharmacovigilance signal-detection algorithms for the FDA adverse event reporting system.

Diffusion weighted imaging of prefrontal cortex in prodromal huntington's disease. Evaluating temporal relations in clinical text: i2b2 Challenge. A controlled greedy supervised approach for co-reference resolution on clinical text. Comprehensive temporal information detection from clinical text: medical events, time, and TLINK identification. Natural Language Processing to identify pneumonia from radiology reports.

The stationary configuration of the knee. MutComFocal: an integrative approach to identifying recurrent and focal genomic alterations in tumor samples. An informational framework to predict reaction of constraints using a reciprocally connected knee model. An algorithmic approach for breakage-fusion-bridge detection in tumor genomes.

Six-week gait retraining program reduces knee adduction moment, reduces pain, and improves function for individuals with medial compartment knee osteoarthritis. Landmark risk prediction of residual life for breast cancer survival. Differential expression of miR in children with Kawasaki disease.

How muscle fiber lengths and velocities affect muscle force generation as humans walk and run at different speeds. An end-to-end system to identify temporal relation in discharge summaries: i2b2 challenge. Web-scale pharmacovigilance: listening to signals from the crowd.

Automating the study of population variation of electrocardiographic features. Referent tracking for treatment optimisation in schizophrenic patients: A case study in applying philosophical ontology to diagnostic algorithms.

Stretching skin: The physiological limit and beyond. GBM volumetry using the 3D Slicer medical image computing platform. Flexing computational muscle: modeling and simulation of musculotendon dynamics. Comparison of four prediction models to discriminate benign from malignant vertebral compression fractures according to MRI feature analysis.

From single nucleotide polymorphism to transcriptional mechanism: a model for FRMD3 in diabetic nephropathy. MetaSeq: privacy preserving meta-analysis of sequencing-based association studies. Insights into diseases of human telomerase from dynamical modeling.

Molecular dynamics simulations for the ranking, evaluation, and refinement of computationally designed proteins. Wessim: a whole-exome sequencing simulator based on in silico exome capture. N-glycoproteome of E Tg2a mouse embryonic stem cells. One-year assessment of surgical outcomes in Class III patients using cone beam computed tomography. Abnormal aldosterone physiology and cardiometabolic risk factors. Classic "broken cell" techniques and newer live cell methods for cell cycle assessment.

Properties of cell death models calibrated and compared using Bayesian approaches. Detecting concept relations in clinical text: insights from a state-of-the-art model. Recursive feature elimination for brain tumor classification using desorption electrospray ionization mass spectrometry imaging.

Automatic segmentation of the left atrium from MRI images using salient feature and contour evolution. Quantifying pathogen surveillance using temporal genomic data. QT interval and antidepressant use: a cross sectional study of electronic health records. Gene expression alterations in bipolar disorder postmortem brains. Multiscale adaptive generalized estimating equations for longitudinal neuroimaging data. Evaluation of methods for modeling transcription factor sequence specificity.

A large-scale evaluation of computational protein function prediction. Federated queries of clinical data repositories: the sum of the parts does not equal the whole. White matter fractional anisotropy is inversely related to anxious symptoms in older adults with atherosclerosis.

Similar risk of depression and anxiety following surgery or hospitalization for Crohn's disease and ulcerative colitis. Exact statistical tests for the intersection of independent lists of genes.

Systems-based approaches toward wound healing. Sexually dimorphic white matter geometry abnormalities in adolescent onset schizophrenia. Selecting cases for whom additional tests can improve prognostication.

Towards mechanism classifiers: expression-anchored Gene Ontology signature predicts clinical outcome in lung adenocarcinoma patients. Towards the creation of a visual ontology of biomedical imaging entities.

The relationship between structural characteristics of challenge documents and ratings of document quality. Applications of ontology design patterns in biomedical ontologies. A semi-automated quantification of pulmonary artery dimensions in computed tomography angiography images. Chapter 9: Analyses using disease ontologies. Abnormalities of middle longitudinal fascicle and disorganization in patients with schizophrenia. Psychiatric co-morbidity is associated with increased risk of surgery in Crohn's disease.

Learning a reliable estimate of the number of fiber directions in diffusion MRI. Spectral label fusion. Longitudinal image registration with non-uniform appearance change. Topology preserving atlas construction from shape data without correspondence using sparse parameters.

Metamorphic geodesic regression. Group analysis of resting-state fMRI by hierarchical Markov random fields. A feature-based developmental model of the infant brain in structural MRI. Fast diffusion tensor registration with exact reorientation and regularization.

Analytic regularization of uniform cubic B-spline deformation fields. Analysis of longitudinal shape variability via subject specific growth modeling. From brain connectivity models to identifying foci of a neurological disorder.

Common variants in psychiatric risk genes predict brain structure at birth. MicroRNA-centric measurement improves functional enrichment analysis of co-expressed and differentially expressed microRNA clusters. Regionally selective atrophy of subcortical structures in prodromal HD as revealed by statistical shape analysis.

OntoMaton: a bioportal powered ontology widget for Google Spreadsheets. The variance of identity-by-descent sharing in the Wright-Fisher model. Subgroup specific incremental value of new markers for risk prediction.

Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis. A chromosome-centric human proteome project C-HPP to characterize the sets of proteins encoded in chromosome Tissue plasminogen activator prevents mortality from sulfur mustard analog-induced airway obstruction.

Fiber tractography based on diffusion tensor imaging compared with high-angular-resolution diffusion imaging with compressed sensing: initial experience. Evaluating incremental values from new predictors with net reclassification improvement in survival analysis. To share or not to share: that is not the question. Muscle contributions to fore-aft and vertical body mass center accelerations over a range of running speeds.

Sharing data for the public good and protecting individual privacy: informatics solutions to combine different goals. Privacy-preserving heterogeneous health data sharing. Pituitary adenoma volumetry with 3D Slicer.

To milliseconds and beyond: challenges in the simulation of protein folding. Regional characterization of longitudinal DT-MRI to study white matter maturation of the early developing brain.

Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls. The plant ontology as a tool for comparative plant anatomy and genomic analyses. Generating fibre orientation maps in human heart models using Poisson interpolation. Ontology-based combinatorial comparative analysis of adverse events associated with killed and live influenza vaccines.

Muscle contributions to vertical and fore-aft accelerations are altered in subjects with crouch gait. ArrayExpress update--trends in database growth and links to data analysis tools. PrePPI: a structure-informed database of protein-protein interactions. Toward an understanding of the short bone phenotype associated with multiple osteochondromas. The Measurement of Local Variation in Shape. A fully implicit finite element method for bidomain models of cardiac electromechanics.

Evaluating the predictive value of biomarkers with stratified case-cohort design. Patellar maltracking is prevalent among patellofemoral pain subjects with patella alta: an upright, weightbearing MRI study. Collaborative software for traditional and translational research. Feasibility of studying brain morphology in major depressive disorder with structural magnetic resonance imaging and clinical data from the electronic medical record: a pilot study.

Toe-in gait reduces the first peak knee adduction moment in patients with medial compartment knee osteoarthritis. Differences in subcortical structures in young adolescents at familial risk for schizophrenia: a preliminary study. Longitudinal analysis of pain in patients with metastatic prostate cancer using natural language processing of medical record text.

Diverse types of genetic variation converge on functional gene networks involved in schizophrenia. Localized differences in caudate and hippocampal shape are associated with schizophrenia but not antipsychotic type.

The influence of sodium- and calcium-regulatory hormone interventions on adipocytokines in obesity and diabetes. Broadening instructional scope with network visualization. Mathematical modeling of collagen turnover in biological tissue. Image registration using radial basis functions with adaptive radius. Combing signals from spontaneous reports and electronic health records for detection of adverse drug reactions.

The structural, connectomic and network covariance of the human brain. Knowledge building insights on biomarkers of arsenic toxicity to keratinocytes and melanocytes. Computational modelling of electrocardiograms: repolarisation and T-wave polarity in the human heart.

Length distributions of identity by descent reveal fine-scale demographic history. Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes. Tor1 regulates protein solubility in Saccharomyces cerevisiae.

The structure of the corpus callosum in obsessive compulsive disorder. On removing interpolation and resampling artifacts in rigid image registration. Multicenter reliability of diffusion tensor imaging. Detecting identity by descent and homozygosity mapping in whole-exome sequencing data. Automated dispersion and orientation analysis for carbon nanotube reinforced polymer composites. A rule based solution to co-reference resolution in clinical text. SHARE: system design and case studies for statistical health information release.

Stretching skeletal muscle: chronic muscle lengthening through sarcomerogenesis. An excess of deleterious variants in VEGF-A pathway genes in Down-syndrome-associated atrioventricular septal defects. A unified inference procedure for a class of measures to assess improvement in risk prediction systems with survival data.

Comparative profiling of miRNA expression of lung adenocarcinoma cells in two-dimensional and three-dimensional cultures. LRpath analysis reveals common pathways dysregulated via DNA methylation across cancer types. Antidepressant response in patients with major depression exposed to NSAIDs: a pharmacovigilance study. Adaptive prior probability and spatial temporal intensity change estimation for segmentation of the one-year-old human brain.

Changes in in vivo knee contact forces through gait modification. Terminology representation guidelines for biomedical ontologies in the semantic web notations. Structure-based prediction of protein-protein interactions on a genome-wide scale.

Anisotropic conductivity of magnetic carbon nanotubes embedded in epoxy matrices. Neuropsychological variability, symptoms, and brain imaging in chronic schizophrenia.

Imaging nigral pathology and clinical progression in Parkinson's disease. Setting up an intronic miRNA database. Extended Broca's area in the functional connectome of language in adults: combined cortical and subcortical single-subject analysis using fMRI and DTI tractography. Comprehensive molecular portraits of human breast tumours.

Associations between white matter microstructure and infants' working memory. Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter. Global probabilistic annotation of metabolic networks enables enzyme discovery. How much muscle strength is required to walk in a crouch gait?

In-bore setup and software for 3T MRI-guided transperineal prostate biopsy. Calibration of multiple in silico tools for predicting pathogenicity of mismatch repair gene missense substitutions. Nanoinformatics: developing new computing applications for nanomedicine.

Designing a public square for research computing. Frontiers in growth and remodeling. Utilizing the integrated difference of two survival functions to quantify the treatment contrast for designing, monitoring, and analyzing a comparative clinical study. A gene expression profile of stem cell pluripotentiality and differentiation is conserved across diverse solid and hematopoietic cancers.

Translational bioinformatics embraces big data. Contributions of muscles to mediolateral ground reaction force over a range of walking speeds. North African Jewish and non-Jewish populations form distinctive, orthogonal clusters. Pharmacokinetics and pharmacodynamics of oral artesunate monotherapy in patients with uncomplicated Plasmodium falciparum malaria in western Cambodia.

Nonmodulation as the mechanism for salt sensitivity of blood pressure in individuals with hypertension and type 2 diabetes mellitus. Reduced fractional anisotropy and axial diffusivity in white matter in 22q Large-scale evaluation of automated clinical note de-identification and its impact on information extraction. Emergence of fatal avian influenza in New England harbor seals. Ontologies as integrative tools for plant science. A role for ephrin-A5 in axonal sprouting, recovery, and activity-dependent plasticity after stroke.

Leveraging models of cell regulation and GWAS data in integrative network-based association studies. Mining the pharmacogenomics literature--a survey of the state of the art. A 3D interactive multi-object segmentation tool using local robust statistics driven active contours. How many neutrophils are enough redux, redux? Comparative protein interactomics of neuroglobin and myoglobin.

Wisdom of crowds for robust gene network inference. Human middle longitudinal fascicle: variations in patterns of anatomical connections. Using domain knowledge and domain-inspired discourse model for coreference resolution for clinical narratives.

Context-specific ontology integration: a bayesian approach. Analyzing patterns of drug use in clinical notes for patient safety. Using temporal patterns in medical records to discern adverse drug events from indications.

Formal concept analysis of disease similarity. Semantator: annotating clinical narratives with semantic web ontologies. Analysis of high-throughput screening assays using cluster enrichment. Reviewing social media use by clinicians. Filtering in the diffeomorphism group and the registration of point sets.

Genetic correction of Huntington's disease phenotypes in induced pluripotent stem cells. Identifying genetic marker sets associated with phenotypes via an efficient adaptive score test. Semiparametric Bayesian local functional models for diffusion tensor tract statistics.

The coming age of data-driven medicine: translational bioinformatics' next frontier. Endoscopic image analysis in semantic space. Genetics insights into the pathogenesis of Kawasaki disease. Coreference analysis in clinical notes: a multi-pass sieve with alternate anaphora resolution modules.

Active learning for clinical text classification: is it better than random sampling? DEFOG: discrete enrichment of functionally organized genes. Bioinformatics advances in saliva diagnostics. Characteristics associated with improved knee extension after strength training for individuals with cerebral palsy and crouch gait. A survey of informatics platforms that enable distributed comparative effectiveness research using multi-institutional heterogenous clinical data.

Brain volume findings in 6-month-old infants at high familial risk for autism. Polymorphisms in the serum- and glucocorticoid-inducible kinase 1 gene are associated with blood pressure and renin response to dietary salt intake. Structural brain atlases: design, rationale, and applications in normal and pathological cohorts.

Image registration for targeted MRI-guided transperineal prostate biopsy. Obstetric complications and risk for conversion to psychosis among individuals at high clinical risk. Template-cut: a pattern-based segmentation paradigm. Towards automatic diabetes case detection and ABCS protocol compliance assessment. Whole brain resting state functional connectivity abnormalities in schizophrenia. Mapping connectivity damage in the case of Phineas Gage.

A supervised framework for resolving coreference in clinical records. Machine learning-based coreference resolution of concepts in clinical documents. Central nervous system endoplasmic reticulum stress in a murine model of type 2 diabetes.

Predicting the metabolic cost of incline walking from muscle activity and walking mechanics. The microRNA expression associated with morphogenesis of breast cancer cells in three-dimensional organotypic culture. Recognition of medication information from discharge summaries using ensembles of classifiers. Coreference resolution of medical concepts in discharge summaries by exploiting contextual information. Bioinformatics and variability in drug response: a protein structural perspective.

Novel data-mining methodologies for adverse drug event discovery and analysis. Evolutionary molecular medicine. Crouched posture maximizes ground reaction forces generated by muscles. Limbic system white matter microstructure and long-term treatment outcome in major depressive disorder: a diffusion tensor imaging study using legacy data.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

Vitamin D3 therapy corrects the tissue sensitivity to angiotensin ii akin to the action of a converting enzyme inhibitor in obese hypertensives: an interventional study. Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus.

Lysine-specific demethylase 1: an epigenetic regulator of salt-sensitive hypertension. Functional organization and its implication in evolution of the human protein-protein interaction network. An image analysis toolbox for high-throughput C.

Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4. The co-morbidity burden of children and young adults with autism spectrum disorders. Protecting count queries in study design. Quantitative tract-based white matter development from birth to age 2years.

A classification approach to coreference in discharge summaries: i2b2 challenge. Structure-based drug screening for G-protein-coupled receptors. Using ontology-based annotation to profile disease research. Unified Medical Language System term occurrences in clinical notes: a large-scale corpus analysis. A patient-driven adaptive prediction technique to improve personalized risk estimation for clinical decision support.

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The DTI connectivity of the human claustrum. Functional evaluation of out-of-the-box text-mining tools for data-mining tasks. Interrogation of a context-specific transcription factor network identifies novel regulators of pluripotency. Atlas-based under-segmentation. Gaussian process interpolation for uncertainty estimation in image registration. Diffeomorphic shape trajectories for improved longitudinal segmentation and statistics.

BrainPrint: identifying subjects by their brain. Subject-specific prediction using nonlinear population modeling: application to early brain maturation from DTI. Hierarchical bayesian modeling, estimation, and sampling for multigroup shape analysis. Evolving insights on how cytosine methylation affects protein-DNA binding. Inferring protein modulation from gene expression data using conditional mutual information.

Cingulum bundle integrity associated with delusions of control in schizophrenia: Preliminary evidence from diffusion-tensor tractography. Characterizing growth patterns in longitudinal MRI using image contrast. Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks. International Conference on Machine Learning. Predicting accurate probabilities with a ranking loss. Machine learning : proceedings of the International Conference.

Abstractions for Genomics. The Living Heart Project: A robust and integrative simulator for human heart function. Multivariate longitudinal shape analysis of human lateral ventricles during the first twenty-four months of life. IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform. Computational modeling of skin: Using stress profiles as predictor for tissue necrosis in reconstructive surgery.

Mode of childbirth and long-term outcomes in women with inflammatory bowel diseases. Co-regulated transcripts associated to cooperating eSNPs define Bi-fan motifs in human gene networks. Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins.

The role of mechanics during brain development. Use it or lose it: multiscale skeletal muscle adaptation to mechanical stimuli. Sparse kernel machine regression for ordinal outcomes. Pegasus: a comprehensive annotation and prediction tool for detection of driver gene fusions in cancer. Decoupling function and anatomy in atlases of functional connectivity patterns: language mapping in tumor patients.

Comparative analysis of metazoan chromatin organization. In search of the determinants of enhancer-promoter interaction specificity. Prenatal antidepressant exposure is associated with risk for attention-deficit hyperactivity disorder but not autism spectrum disorder in a large health system. SELEX-seq: a method for characterizing the complete repertoire of binding site preferences for transcription factor complexes.

Complex pathways in folding of protein G explored by simulation and experiment. Evolution of the central sulcus morphology in primates. Treatment selections using risk-benefit profiles based on data from comparative randomized clinical trials with multiple endpoints. Multiple LacI-mediated loops revealed by Bayesian statistics and tethered particle motion. Classification of CT pulmonary angiography reports by presence, chronicity, and location of pulmonary embolism with natural language processing.

Differentially private distributed logistic regression using private and public data. Data-driven discovery of seasonally linked diseases from an Electronic Health Records system. Multi-atlas segmentation with particle-based group-wise image registration. Impact of family history on prostate cancer mortality in white men undergoing prostate specific antigen based screening.

Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records. Lipoprotein particle concentrations in children and adults following Kawasaki disease. An autism case history to review the systematic analysis of large-scale data to refine the diagnosis and treatment of neuropsychiatric disorders.

Robust Radiomics feature quantification using semiautomatic volumetric segmentation. Characterization of living skin using multi-view stereo and isogeometric analysis.

Privacy preserving RBF kernel support vector machine. A mechanical model predicts morphological abnormalities in the developing human brain. Localized abnormalities in the cingulum bundle in patients with schizophrenia: a Diffusion Tensor tractography study.

Prenatal cocaine effects on brain structure in early infancy. Toward personalizing treatment for depression: predicting diagnosis and severity. ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2.

Morphometry of anatomical shape complexes with dense deformations and sparse parameters. Characterizing a collective and dynamic component of chromatin immunoprecipitation enrichment profiles in yeast.

The elusive evidence for chromothripsis. Harnessing natural sequence variation to dissect posttranscriptional regulatory networks in yeast. Multi-Channel neurodegenerative pattern analysis and its application in Alzheimer's disease characterization. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society.

Inferring gene ontologies from pairwise similarity data. Dysmorphogenic effects of first trimester-equivalent ethanol exposure in mice: a magnetic resonance microscopy-based study. Fluoroquinolone resistant rectal colonization predicts risk of infectious complications after transrectal prostate biopsy.

Integrative biology identifies shared transcriptional networks in CKD. OpenIGTLink interface for state control and visualisation of a robot for image-guided therapy systems.

MAGI: a Node. Structural bioinformatics of the interactome. A community effort to assess and improve drug sensitivity prediction algorithms. Natural language processing in biomedicine: a unified system architecture overview. Evaluating the effects of machine pre-annotation and an interactive annotation interface on manual de-identification of clinical text. Transfer learning based clinical concept extraction on data from multiple sources. Structural and connectomic neuroimaging for the personalized study of longitudinal alterations in cortical shape, thickness and connectivity after traumatic brain injury.

Meshless Modeling of Deformable Shapes and their Motion. Patient-level temporal aggregation for text-based asthma status ascertainment. Efficient inverse isoparametric mapping algorithm for whole-body computed tomography registration using deformations predicted by nonlinear finite element modeling. Response of Escherichia coli growth rate to osmotic shock.

A graph algebra for scalable visual analytics. Multiatlas segmentation as nonparametric regression. Coping with confounds in multivoxel pattern analysis: what should we do about reaction time differences?

Automatic segmentation of head and neck CT images for radiotherapy treatment planning using multiple atlases, statistical appearance models, and geodesic active contours. Evaluating marker-guided treatment selection strategies. Variations of dynamic contrast-enhanced magnetic resonance imaging in evaluation of breast cancer therapy response: a multicenter data analysis challenge. Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development.

Knowledge-based fragment binding prediction. A complete system for automatic extraction of left ventricular myocardium from CT images using shape segmentation and contour evolution.

Ensuring privacy in the study of pathogen genetics. Mutual information as a measure of image quality for 3D dynamic lung imaging with EIT.

Identifying regulatory mechanisms underlying tumorigenesis using locus expression signature analysis. Response to letters regarding article, "unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine". Population-level evidence for an autoimmune etiology of epilepsy.

Joint modeling of imaging and genetics. Geodesic shape regression in the framework of currents. Bayesian segmentation of atrium wall using globally-optimal graph cuts on 3D meshes. Group-wise cortical correspondence via sulcal curve-constrained entropy minimization. Sparse projections of medical images onto manifolds. A longitudinal functional analysis framework for analysis of white matter tract statistics.

Aldosterone dysregulation with aging predicts renal vascular function and cardiovascular risk. Bayesian energy landscape tilting: towards concordant models of molecular ensembles. Empirical Bayes methods enable advanced population-level analyses of single-molecule FRET experiments. Developing image processing meta-algorithms with data mining of multiple metrics.

Cerebral white matter abnormalities and their associations with negative but not positive symptoms of schizophrenia. Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases.

Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma. High precision prediction of functional sites in protein structures. MAAMD: a workflow to standardize meta-analyses and comparison of affymetrix microarray data. Neuroinformatics challenges to the structural, connectomic, functional and electrophysiological multimodal imaging of human traumatic brain injury. Changes in tibiofemoral forces due to variations in muscle activity during walking.

Pregnancy in women with a history of Kawasaki disease: management and outcomes. Semantics in support of biodiversity knowledge discovery: an introduction to the biological collections ontology and related ontologies. The automated function prediction SIG looks back at and prepares for Automated detection of off-label drug use.

Multifold Bayesian kernelization in Alzheimer's diagnosis. Geodesic distances to landmarks for dense correspondence on ensembles of complex shapes.

Systematic network lesioning reveals the core white matter scaffold of the human brain. Multi-atlas segmentation of subcortical brain structures via the AutoSeg software pipeline. SAVI: a statistical algorithm for variant frequency identification. On the mechanics of growing thin biological membranes. Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease.

Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes. When you can't tell when it hurts: a preliminary algorithm to assess pain in patients who can't communicate. Crowdsourcing the verification of relationships in biomedical ontologies. Building and evaluating an ontology-based tool for reasoning about consent permission. Effects of polymerization and nucleotide identity on the conformational dynamics of the bacterial actin homolog MreB.

Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness. Annotating the structure and components of a nanoparticle formulation using computable string expressions. Rare copy number variation in treatment-resistant major depressive disorder. DTIPrep: quality control of diffusion-weighted images. Semi-Automatic Parcellation of the Corpus Striatum.

Validation of catheter segmentation for MR-guided gynecologic cancer brachytherapy. Contour-driven regression for label inference in atlas-based segmentation. Particle-guided image registration. Detecting epileptic regions based on global brain connectivity patterns. Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia. Specificity of regulatory T cells that modulate vascular inflammation.

Differential privacy based on importance weighting. Web-based tools for modelling and analysis of multivariate data: California ozone pollution activity. More accurate neuronavigation data provided by biomechanical modeling instead of rigid registration. MutPred Splice: machine learning-based prediction of exonic variants that disrupt splicing. Word sense disambiguation in the clinical domain: a comparison of knowledge-rich and knowledge-poor unsupervised methods.

Automatic lymphoma classification with sentence subgraph mining from pathology reports. Regional neuroplastic brain changes in patients with chronic inflammatory and non-inflammatory visceral pain. A midas plugin to enable construction of reproducible web-based image processing pipelines. Serum inflammatory markers and risk of colorectal cancer in patients with inflammatory bowel diseases. A framework for longitudinal data analysis via shape regression. Fast approximate surface evolution in arbitrary dimension.

Studying PubMed usages in the field for complex problem solving: Implications for tool design. Atrial fibrillation ablation outcome is predicted by left atrial remodeling on MRI. Stochastic Image Registration with User Constraints.

Fiber feature map based landmark initialization for highly deformable DTI registration. Quality Control of Diffusion Weighted Images.

The environment ontology: contextualising biological and biomedical entities. Omnibus risk assessment via accelerated failure time kernel machine modeling. Treatment response in kawasaki disease is associated with sialylation levels of endogenous but not therapeutic intravenous immunoglobulin G.

Comorbidity clusters in autism spectrum disorders: an electronic health record time-series analysis. Mining the ultimate phenome repository. The neurological disease ontology. Discussion of ''Biomedical informatics: we are what we publish''.

Amplification and thrifty single-molecule sequencing of recurrent somatic structural variations. Genome-wide DNA methylation changes with age in disease free human skeletal muscle. Calculations of the electric fields in liquid solutions. Learning signals of adverse drug-drug interactions from the unstructured text of electronic health records.

Network analysis of unstructured EHR data for clinical research. Profiling risk factors for chronic uveitis in juvenile idiopathic arthritis: a new model for EHR-based research. Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity.

Associations of smoking and alcohol consumption with disease activity and functional status in rheumatoid arthritis. Predicting the restricted mean event time with the subject's baseline covariates in survival analysis. Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia. Genetic robustness and functional evolution of gene duplicates. Three-dimensional treatment outcomes in Class II patients treated with the Herbst appliance: a pilot study.

Chronology of your health events: approaches to extracting temporal relations from medical narratives. OnTheFly: a database of Drosophila melanogaster transcription factors and their binding sites.

SGPP: spatial Gaussian predictive process models for neuroimaging data. State of the human proteome in as viewed through PeptideAtlas: comparing the kidney, urine, and plasma proteomes for the biology- and disease-driven Human Proteome Project. Reviewing the ketamine model for schizophrenia. Modeling disease severity in multiple sclerosis using electronic health records. Growing matter: a review of growth in living systems.

Predictors of plasma and urinary catecholamine levels in normotensive and hypertensive men and women. Towards generating a patient's timeline: extracting temporal relationships from clinical notes. Improved segmentation of white matter tracts with adaptive Riemannian metrics.

In silico approaches and the role of ontologies in aging research. Using search queries for malaria surveillance, Thailand. Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome. Three-dimensional analysis of maxillary changes associated with facemask and rapid maxillary expansion compared with bone anchored maxillary protraction.

Neuroimaging of structural pathology and connectomics in traumatic brain injury: Toward personalized outcome prediction. Topology of viral evolution. Regional 3D superimposition to assess temporomandibular joint condylar morphology. Leveraging electronic health records to notify pediatric patients of a drug recall. Mining clinical text for signals of adverse drug-drug interactions.

Application of universal stress proteins in probing the dynamics of potent degraders in complex terephthalate metagenome. Automated chart review for asthma cohort identification using natural language processing: an exploratory study. Nocturnal continuous glucose and sleep stage data in adults with type 1 diabetes in real-world conditions. Human neuroimaging as a "Big Data" science. Distinct splice variants and pathway enrichment in the cell-line models of aggressive human breast cancer subtypes.

Localized Sparse Code Gradient in Alzheimer's disease staging. Conference proceedings Annual Conference. Nucleotide sequence alignment using sparse coding and belief propagation. Discovering body site and severity modifiers in clinical texts. Improved de-identification of physician notes through integrative modeling of both public and private medical text.

Temporal relation discovery between events and temporal expressions identified in clinical narrative. FMEM: functional mixed effects modeling for the analysis of longitudinal white matter Tract data.

A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk. Neural encoding of acupuncture needling sensations: evidence from a FMRI study. Seasonality of Kawasaki disease: a global perspective. Instrumentation bias in the use and evaluation of scientific software: recommendations for reproducible practices in the computational sciences.

Automatic segmentation of the left atrium from MR images via variational region growing with a moments-based shape prior.

Combining an expert-based medical entity recognizer to a machine-learning system: methods and a case study. Opportunities for genomic clinical decision support interventions. A novel strategy to identify the critical conditions for growth-induced instabilities. Temporomandibular joint condylar changes following maxillomandibular advancement and articular disc repositioning.

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. Sex-related differences of cortical thickness in patients with chronic abdominal pain. On the design of clone-based haplotyping. A molecular signature predictive of indolent prostate cancer.

Extraction of events and temporal expressions from clinical narratives. Tissue-specific profiling reveals transcriptome alterations in Arabidopsis mutants lacking morphological phenotypes. Assessment of biomarkers for risk prediction with nested case-control studies. Electroencephalographic inverse localization of brain activity in acute traumatic brain injury as a guide to surgery, monitoring and treatment.

A new tool for sharing and querying of clinical documents modeled using HL7 Version 3 standard. Prostate cancer detection and diagnosis: the role of MR and its comparison with other diagnostic modalities--a radiologist's perspective. Automated skin segmentation in ultrasonic evaluation of skin toxicity in breast cancer radiotherapy. Using twitter to examine smoking behavior and perceptions of emerging tobacco products.

PhenDisco: phenotype discovery system for the database of genotypes and phenotypes. Virmid: accurate detection of somatic mutations with sample impurity inference. Identification of Functional Regulatory Residues of the? Automatic prediction of rheumatoid arthritis disease activity from the electronic medical records.

On the effect of prestrain and residual stress in thin biological membranes. Multimodal deformable registration of traumatic brain injury MR volumes via the Bhattacharyya distance.

Toward a comprehensive framework for the spatiotemporal statistical analysis of longitudinal shape data. Identifying phenotypic signatures of neuropsychiatric disorders from electronic medical records. Classifying temporal relations in clinical data: A hybrid, knowledge-rich approach. Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders.

Mapping cortical atrophy in Parkinson's disease patients with dementia. Lipid and lipoprotein levels and trend in rheumatoid arthritis compared to the general population. Extending the NegEx lexicon for multiple languages. ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer. The integrated landscape of driver genomic alterations in glioblastoma.

Shape abnormalities of the caudate nucleus correlate with poorer gait and balance: results from a subset of the LADIS study. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. Magnetic resonance microscopy-based analyses of the neuroanatomical effects of gestational day 9 ethanol exposure in mice. MedTime: a temporal information extraction system for clinical narratives.

Syntactic parsing of clinical text: guideline and corpus development with handling ill-formed sentences. Immune-monitoring in Kawasaki disease patients treated with infliximab and intravenous immunoglobulin. A locally adaptive regularization based on anisotropic diffusion for deformable image registration of sliding organs.

Interactive medical image segmentation using PDE control of active contours. Localizing the human primary auditory cortex in vivo using structural MRI. Fast local trust region technique for diffusion tensor registration using exact reorientation and regularization. Annotating temporal information in clinical narratives.

Semantator: Semantic annotator for converting biomedical text to linked data. From connectivity models to region labels: identifying foci of a neurological disorder. Computational semantics in clinical text. Longitudinal image registration with temporally-dependent image similarity measure. Variants in exons and in transcription factors affect gene expression in trans. Ground state destabilization by anionic nucleophiles contributes to the activity of phosphoryl transfer enzymes.

Statistical shape modeling of cam femoroacetabular impingement. Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine. Sarcomere lengths in human extensor carpi radialis brevis measured by microendoscopy.

Inference of historical migration rates via haplotype sharing. Improving data and knowledge management to better integrate health care and research. Adopting nested case-control quota sampling designs for the evaluation of risk markers. Decreased axial diffusivity within language connections: A possible biomarker of schizophrenia risk. Sparse texture active contour. Computational modeling of chemo-electro-mechanical coupling: a novel implicit monolithic finite element approach.

Increased gray matter diffusion anisotropy in patients with persistent post-concussive symptoms following mild traumatic brain injury. Privacy technology to support data sharing for comparative effectiveness research: a systematic review. Long-term 3-dimensional stability of mandibular advancement surgery.

Using Genome Query Language to uncover genetic variation. Systematic improvement of a classical molecular model of water. Mechanical consequences of cell-wall turnover in the elongation of a Gram-positive bacterium. Forward and inverse electroencephalographic modeling in health and in acute traumatic brain injury.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. Automatic delineation of the myocardial wall from CT images via shape segmentation and variational region growing. Hypothalamic proteoglycan syndecan-3 is a novel cocaine addiction resilience factor. Evaluating genome architecture of a complex region via generalized bipartite matching.

Extracting physician group intelligence from electronic health records to support evidence based medicine. Dynamic Active Contours for Visual Tracking. Spatial-temporal atlas of human fetal brain development during the early second trimester. Practice-based evidence: profiling the safety of cilostazol by text-mining of clinical notes. Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls.

A rolling constraint reproduces ground reaction forces and moments in dynamic simulations of walking, running, and crouch gait.

Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway. Inferences on the biochemical and environmental regulation of universal stress proteins from Schistosomiasis parasites. Impact of sex and gonadal steroids on neonatal brain structure. Morse-Smale Regression. Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America.

A flexible framework for recognizing events, temporal expressions, and temporal relations in clinical text. Human middle longitudinal fascicle: segregation and behavioral-clinical implications of two distinct fiber connections linking temporal pole and superior temporal gyrus with the angular gyrus or superior parietal lobule using multi-tensor tractography.

Diffusion imaging quality control via entropy of principal direction distribution. Temporal reasoning over clinical text: the state of the art. Beyond NPM-anaplastic lymphoma kinase driven lymphomagenesis: alternative drivers in anaplastic large cell lymphoma. Improving breast cancer survival analysis through competition-based multidimensional modeling.

Reprever: resolving low-copy duplicated sequences using template driven assembly. HIV infection reveals widespread expansion of novel centromeric human endogenous retroviruses. Surgery, virtual reality, and the future. Enhanced modeling via network theory: Adaptive sampling of Markov state models.

Growth on demand: Reviewing the mechanobiology of stretched skin. Optical flow estimation for flame detection in videos. Genetic contributions to changes of fiber tracts of ventral visual stream in 22q Lateral ventricle morphology analysis via mean latitude axis.

On the mechanics of continua with boundary energies and growing surfaces. Combining rules and machine learning for extraction of temporal expressions and events from clinical narratives. Heterogeneity of tumor-induced gene expression changes in the human metabolic network. Innovations in proteomic profiling of cancers: alternative splice variants as a new class of cancer biomarker candidates and bridging of proteomics with structural biology. Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer.

Dominant effects of the Huntington's disease HTT CAG repeat length are captured in gene-expression data sets by a continuous analysis mathematical modeling strategy. Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver. Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Towards improved ultrasound-based analysis and 3D visualization of the fetal brain using the 3D Slicer.

Eventual situations for timeline extraction from clinical reports. A hybrid system for temporal information extraction from clinical text. Pharmacovigilance using clinical notes. Performance of pharmacovigilance signal-detection algorithms for the FDA adverse event reporting system.

Diffusion weighted imaging of prefrontal cortex in prodromal huntington's disease. Evaluating temporal relations in clinical text: i2b2 Challenge. A controlled greedy supervised approach for co-reference resolution on clinical text. Comprehensive temporal information detection from clinical text: medical events, time, and TLINK identification. Natural Language Processing to identify pneumonia from radiology reports. The stationary configuration of the knee. MutComFocal: an integrative approach to identifying recurrent and focal genomic alterations in tumor samples.

An informational framework to predict reaction of constraints using a reciprocally connected knee model. An algorithmic approach for breakage-fusion-bridge detection in tumor genomes. Six-week gait retraining program reduces knee adduction moment, reduces pain, and improves function for individuals with medial compartment knee osteoarthritis.

Landmark risk prediction of residual life for breast cancer survival. Differential expression of miR in children with Kawasaki disease. How muscle fiber lengths and velocities affect muscle force generation as humans walk and run at different speeds. An end-to-end system to identify temporal relation in discharge summaries: i2b2 challenge. Web-scale pharmacovigilance: listening to signals from the crowd. Automating the study of population variation of electrocardiographic features.

Referent tracking for treatment optimisation in schizophrenic patients: A case study in applying philosophical ontology to diagnostic algorithms. Stretching skin: The physiological limit and beyond. GBM volumetry using the 3D Slicer medical image computing platform. Flexing computational muscle: modeling and simulation of musculotendon dynamics. Comparison of four prediction models to discriminate benign from malignant vertebral compression fractures according to MRI feature analysis.

From single nucleotide polymorphism to transcriptional mechanism: a model for FRMD3 in diabetic nephropathy. MetaSeq: privacy preserving meta-analysis of sequencing-based association studies.

Insights into diseases of human telomerase from dynamical modeling. Molecular dynamics simulations for the ranking, evaluation, and refinement of computationally designed proteins.

Wessim: a whole-exome sequencing simulator based on in silico exome capture. N-glycoproteome of E Tg2a mouse embryonic stem cells. One-year assessment of surgical outcomes in Class III patients using cone beam computed tomography. Abnormal aldosterone physiology and cardiometabolic risk factors. Classic "broken cell" techniques and newer live cell methods for cell cycle assessment. Properties of cell death models calibrated and compared using Bayesian approaches.

Detecting concept relations in clinical text: insights from a state-of-the-art model. Recursive feature elimination for brain tumor classification using desorption electrospray ionization mass spectrometry imaging.

Automatic segmentation of the left atrium from MRI images using salient feature and contour evolution. Quantifying pathogen surveillance using temporal genomic data. QT interval and antidepressant use: a cross sectional study of electronic health records.

Gene expression alterations in bipolar disorder postmortem brains. Multiscale adaptive generalized estimating equations for longitudinal neuroimaging data.

Evaluation of methods for modeling transcription factor sequence specificity. A large-scale evaluation of computational protein function prediction. Federated queries of clinical data repositories: the sum of the parts does not equal the whole.

White matter fractional anisotropy is inversely related to anxious symptoms in older adults with atherosclerosis. Similar risk of depression and anxiety following surgery or hospitalization for Crohn's disease and ulcerative colitis. Exact statistical tests for the intersection of independent lists of genes. Systems-based approaches toward wound healing. Sexually dimorphic white matter geometry abnormalities in adolescent onset schizophrenia. Selecting cases for whom additional tests can improve prognostication.

Towards mechanism classifiers: expression-anchored Gene Ontology signature predicts clinical outcome in lung adenocarcinoma patients.

Towards the creation of a visual ontology of biomedical imaging entities. The relationship between structural characteristics of challenge documents and ratings of document quality. Applications of ontology design patterns in biomedical ontologies. A semi-automated quantification of pulmonary artery dimensions in computed tomography angiography images.

Chapter 9: Analyses using disease ontologies. Abnormalities of middle longitudinal fascicle and disorganization in patients with schizophrenia. Psychiatric co-morbidity is associated with increased risk of surgery in Crohn's disease. Learning a reliable estimate of the number of fiber directions in diffusion MRI. Spectral label fusion. Longitudinal image registration with non-uniform appearance change.

Topology preserving atlas construction from shape data without correspondence using sparse parameters. Metamorphic geodesic regression. Group analysis of resting-state fMRI by hierarchical Markov random fields. A feature-based developmental model of the infant brain in structural MRI. Fast diffusion tensor registration with exact reorientation and regularization. Analytic regularization of uniform cubic B-spline deformation fields. Analysis of longitudinal shape variability via subject specific growth modeling.

From brain connectivity models to identifying foci of a neurological disorder. Common variants in psychiatric risk genes predict brain structure at birth.

MicroRNA-centric measurement improves functional enrichment analysis of co-expressed and differentially expressed microRNA clusters. Regionally selective atrophy of subcortical structures in prodromal HD as revealed by statistical shape analysis.

OntoMaton: a bioportal powered ontology widget for Google Spreadsheets. The variance of identity-by-descent sharing in the Wright-Fisher model. Subgroup specific incremental value of new markers for risk prediction. Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis.

A chromosome-centric human proteome project C-HPP to characterize the sets of proteins encoded in chromosome Tissue plasminogen activator prevents mortality from sulfur mustard analog-induced airway obstruction. Fiber tractography based on diffusion tensor imaging compared with high-angular-resolution diffusion imaging with compressed sensing: initial experience.

Evaluating incremental values from new predictors with net reclassification improvement in survival analysis. To share or not to share: that is not the question. Muscle contributions to fore-aft and vertical body mass center accelerations over a range of running speeds. Sharing data for the public good and protecting individual privacy: informatics solutions to combine different goals.

Privacy-preserving heterogeneous health data sharing. Pituitary adenoma volumetry with 3D Slicer. To milliseconds and beyond: challenges in the simulation of protein folding.

Regional characterization of longitudinal DT-MRI to study white matter maturation of the early developing brain. Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls.

The plant ontology as a tool for comparative plant anatomy and genomic analyses. Generating fibre orientation maps in human heart models using Poisson interpolation. Ontology-based combinatorial comparative analysis of adverse events associated with killed and live influenza vaccines.

Muscle contributions to vertical and fore-aft accelerations are altered in subjects with crouch gait. ArrayExpress update--trends in database growth and links to data analysis tools. PrePPI: a structure-informed database of protein-protein interactions. Toward an understanding of the short bone phenotype associated with multiple osteochondromas.

The Measurement of Local Variation in Shape. A fully implicit finite element method for bidomain models of cardiac electromechanics. Evaluating the predictive value of biomarkers with stratified case-cohort design. Patellar maltracking is prevalent among patellofemoral pain subjects with patella alta: an upright, weightbearing MRI study. Collaborative software for traditional and translational research. Feasibility of studying brain morphology in major depressive disorder with structural magnetic resonance imaging and clinical data from the electronic medical record: a pilot study.

Toe-in gait reduces the first peak knee adduction moment in patients with medial compartment knee osteoarthritis. Differences in subcortical structures in young adolescents at familial risk for schizophrenia: a preliminary study. Longitudinal analysis of pain in patients with metastatic prostate cancer using natural language processing of medical record text. Diverse types of genetic variation converge on functional gene networks involved in schizophrenia. Localized differences in caudate and hippocampal shape are associated with schizophrenia but not antipsychotic type.

The influence of sodium- and calcium-regulatory hormone interventions on adipocytokines in obesity and diabetes. Broadening instructional scope with network visualization. Mathematical modeling of collagen turnover in biological tissue. Image registration using radial basis functions with adaptive radius. Combing signals from spontaneous reports and electronic health records for detection of adverse drug reactions.

The structural, connectomic and network covariance of the human brain. Knowledge building insights on biomarkers of arsenic toxicity to keratinocytes and melanocytes.

Computational modelling of electrocardiograms: repolarisation and T-wave polarity in the human heart.

Length distributions of identity by descent reveal fine-scale demographic history. Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes. Tor1 regulates protein solubility in Saccharomyces cerevisiae.

The structure of the corpus callosum in obsessive compulsive disorder. On removing interpolation and resampling artifacts in rigid image registration. Multicenter reliability of diffusion tensor imaging. Detecting identity by descent and homozygosity mapping in whole-exome sequencing data. Automated dispersion and orientation analysis for carbon nanotube reinforced polymer composites. A rule based solution to co-reference resolution in clinical text.

SHARE: system design and case studies for statistical health information release. Stretching skeletal muscle: chronic muscle lengthening through sarcomerogenesis. An excess of deleterious variants in VEGF-A pathway genes in Down-syndrome-associated atrioventricular septal defects. A unified inference procedure for a class of measures to assess improvement in risk prediction systems with survival data.

Comparative profiling of miRNA expression of lung adenocarcinoma cells in two-dimensional and three-dimensional cultures. LRpath analysis reveals common pathways dysregulated via DNA methylation across cancer types. Antidepressant response in patients with major depression exposed to NSAIDs: a pharmacovigilance study. Adaptive prior probability and spatial temporal intensity change estimation for segmentation of the one-year-old human brain.

Changes in in vivo knee contact forces through gait modification. Terminology representation guidelines for biomedical ontologies in the semantic web notations. Structure-based prediction of protein-protein interactions on a genome-wide scale. Anisotropic conductivity of magnetic carbon nanotubes embedded in epoxy matrices. Neuropsychological variability, symptoms, and brain imaging in chronic schizophrenia.

Imaging nigral pathology and clinical progression in Parkinson's disease. Setting up an intronic miRNA database. Extended Broca's area in the functional connectome of language in adults: combined cortical and subcortical single-subject analysis using fMRI and DTI tractography.

Comprehensive molecular portraits of human breast tumours. Associations between white matter microstructure and infants' working memory. Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter. Global probabilistic annotation of metabolic networks enables enzyme discovery. How much muscle strength is required to walk in a crouch gait? In-bore setup and software for 3T MRI-guided transperineal prostate biopsy.

Calibration of multiple in silico tools for predicting pathogenicity of mismatch repair gene missense substitutions. Nanoinformatics: developing new computing applications for nanomedicine. Designing a public square for research computing. Frontiers in growth and remodeling. Utilizing the integrated difference of two survival functions to quantify the treatment contrast for designing, monitoring, and analyzing a comparative clinical study.

A gene expression profile of stem cell pluripotentiality and differentiation is conserved across diverse solid and hematopoietic cancers. Translational bioinformatics embraces big data. Contributions of muscles to mediolateral ground reaction force over a range of walking speeds. North African Jewish and non-Jewish populations form distinctive, orthogonal clusters.

Pharmacokinetics and pharmacodynamics of oral artesunate monotherapy in patients with uncomplicated Plasmodium falciparum malaria in western Cambodia. Nonmodulation as the mechanism for salt sensitivity of blood pressure in individuals with hypertension and type 2 diabetes mellitus. Reduced fractional anisotropy and axial diffusivity in white matter in 22q Large-scale evaluation of automated clinical note de-identification and its impact on information extraction.

Emergence of fatal avian influenza in New England harbor seals. Ontologies as integrative tools for plant science. A role for ephrin-A5 in axonal sprouting, recovery, and activity-dependent plasticity after stroke. Leveraging models of cell regulation and GWAS data in integrative network-based association studies.

Mining the pharmacogenomics literature--a survey of the state of the art. A 3D interactive multi-object segmentation tool using local robust statistics driven active contours. How many neutrophils are enough redux, redux? Comparative protein interactomics of neuroglobin and myoglobin. Wisdom of crowds for robust gene network inference. Human middle longitudinal fascicle: variations in patterns of anatomical connections.

Using domain knowledge and domain-inspired discourse model for coreference resolution for clinical narratives. Context-specific ontology integration: a bayesian approach. Analyzing patterns of drug use in clinical notes for patient safety.

Using temporal patterns in medical records to discern adverse drug events from indications. Formal concept analysis of disease similarity. Semantator: annotating clinical narratives with semantic web ontologies. Analysis of high-throughput screening assays using cluster enrichment.

Reviewing social media use by clinicians. Filtering in the diffeomorphism group and the registration of point sets. Genetic correction of Huntington's disease phenotypes in induced pluripotent stem cells. Identifying genetic marker sets associated with phenotypes via an efficient adaptive score test.

Semiparametric Bayesian local functional models for diffusion tensor tract statistics. The coming age of data-driven medicine: translational bioinformatics' next frontier.

Endoscopic image analysis in semantic space. Genetics insights into the pathogenesis of Kawasaki disease. Coreference analysis in clinical notes: a multi-pass sieve with alternate anaphora resolution modules.

Active learning for clinical text classification: is it better than random sampling? DEFOG: discrete enrichment of functionally organized genes.

Bioinformatics advances in saliva diagnostics. Characteristics associated with improved knee extension after strength training for individuals with cerebral palsy and crouch gait.

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Longitudinal quantification and visualization of intracerebral haemorrhage using multimodal magnetic resonance and diffusion tensor imaging. Segmentation of cerebrovascular pathologies in stroke patients with spatial and shape priors. Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia. Is my model good enough? Best practices for verification and validation of musculoskeletal models and simulations of movement.

Multi-modal robust inverse-consistent linear registration. Differences in muscle activity between natural forefoot and rearfoot strikers during running. Integration of genomic data enables selective discovery of breast cancer drivers.

Comment on: ''Zoo or savannah? Choice of training ground for evidence-based pharmacovigilance''. Multimodal neuroimaging feature learning for multiclass diagnosis of Alzheimer's disease. A community computational challenge to predict the activity of pairs of compounds. Discovering chemistry with an ab initio nanoreactor. Text mining in cancer gene and pathway prioritization. Statistical estimation of physiological brain age as a descriptor of senescence rate during adulthood. Long-term phenotypic evolution of bacteria.

The genetic basis of chronic mountain sickness. ArrayExpress update--simplifying data submissions. Choosing blindly but wisely: differentially private solicitation of DNA datasets for disease marker discovery. Disease Ontology update: an expanded and updated database of human diseases for linking biomedical knowledge through disease data.

Automatic identification of methotrexate-induced liver toxicity in patients with rheumatoid arthritis from the electronic medical record. Computational modeling of hypertensive growth in the human carotid artery. Systems biology. Conditional density-based analysis of T cell signaling in single-cell data.

The DTI connectivity of the human claustrum. Functional evaluation of out-of-the-box text-mining tools for data-mining tasks. Interrogation of a context-specific transcription factor network identifies novel regulators of pluripotency. Atlas-based under-segmentation. Gaussian process interpolation for uncertainty estimation in image registration. Diffeomorphic shape trajectories for improved longitudinal segmentation and statistics.

BrainPrint: identifying subjects by their brain. Subject-specific prediction using nonlinear population modeling: application to early brain maturation from DTI. Hierarchical bayesian modeling, estimation, and sampling for multigroup shape analysis. Evolving insights on how cytosine methylation affects protein-DNA binding. Inferring protein modulation from gene expression data using conditional mutual information.

Cingulum bundle integrity associated with delusions of control in schizophrenia: Preliminary evidence from diffusion-tensor tractography. Characterizing growth patterns in longitudinal MRI using image contrast.

Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks. International Conference on Machine Learning. Predicting accurate probabilities with a ranking loss. Machine learning : proceedings of the International Conference. Abstractions for Genomics. The Living Heart Project: A robust and integrative simulator for human heart function.

Multivariate longitudinal shape analysis of human lateral ventricles during the first twenty-four months of life. IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform.

Computational modeling of skin: Using stress profiles as predictor for tissue necrosis in reconstructive surgery. Mode of childbirth and long-term outcomes in women with inflammatory bowel diseases.

Co-regulated transcripts associated to cooperating eSNPs define Bi-fan motifs in human gene networks. Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins.

The role of mechanics during brain development. Use it or lose it: multiscale skeletal muscle adaptation to mechanical stimuli. Sparse kernel machine regression for ordinal outcomes.

Pegasus: a comprehensive annotation and prediction tool for detection of driver gene fusions in cancer. Decoupling function and anatomy in atlases of functional connectivity patterns: language mapping in tumor patients. Comparative analysis of metazoan chromatin organization. In search of the determinants of enhancer-promoter interaction specificity. Prenatal antidepressant exposure is associated with risk for attention-deficit hyperactivity disorder but not autism spectrum disorder in a large health system.

SELEX-seq: a method for characterizing the complete repertoire of binding site preferences for transcription factor complexes. Complex pathways in folding of protein G explored by simulation and experiment.

Evolution of the central sulcus morphology in primates. Treatment selections using risk-benefit profiles based on data from comparative randomized clinical trials with multiple endpoints. Multiple LacI-mediated loops revealed by Bayesian statistics and tethered particle motion. Classification of CT pulmonary angiography reports by presence, chronicity, and location of pulmonary embolism with natural language processing.

Differentially private distributed logistic regression using private and public data. Data-driven discovery of seasonally linked diseases from an Electronic Health Records system. Multi-atlas segmentation with particle-based group-wise image registration.

Impact of family history on prostate cancer mortality in white men undergoing prostate specific antigen based screening. Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records. Lipoprotein particle concentrations in children and adults following Kawasaki disease.

An autism case history to review the systematic analysis of large-scale data to refine the diagnosis and treatment of neuropsychiatric disorders. Robust Radiomics feature quantification using semiautomatic volumetric segmentation. Characterization of living skin using multi-view stereo and isogeometric analysis.

Privacy preserving RBF kernel support vector machine. A mechanical model predicts morphological abnormalities in the developing human brain. Localized abnormalities in the cingulum bundle in patients with schizophrenia: a Diffusion Tensor tractography study. Prenatal cocaine effects on brain structure in early infancy. Toward personalizing treatment for depression: predicting diagnosis and severity. ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2.

Morphometry of anatomical shape complexes with dense deformations and sparse parameters. Characterizing a collective and dynamic component of chromatin immunoprecipitation enrichment profiles in yeast. The elusive evidence for chromothripsis. Harnessing natural sequence variation to dissect posttranscriptional regulatory networks in yeast.

Multi-Channel neurodegenerative pattern analysis and its application in Alzheimer's disease characterization. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society.

Inferring gene ontologies from pairwise similarity data. Dysmorphogenic effects of first trimester-equivalent ethanol exposure in mice: a magnetic resonance microscopy-based study. Fluoroquinolone resistant rectal colonization predicts risk of infectious complications after transrectal prostate biopsy. Integrative biology identifies shared transcriptional networks in CKD.

OpenIGTLink interface for state control and visualisation of a robot for image-guided therapy systems. MAGI: a Node. Structural bioinformatics of the interactome. A community effort to assess and improve drug sensitivity prediction algorithms. Natural language processing in biomedicine: a unified system architecture overview. Evaluating the effects of machine pre-annotation and an interactive annotation interface on manual de-identification of clinical text.

Transfer learning based clinical concept extraction on data from multiple sources. Structural and connectomic neuroimaging for the personalized study of longitudinal alterations in cortical shape, thickness and connectivity after traumatic brain injury. Meshless Modeling of Deformable Shapes and their Motion. Patient-level temporal aggregation for text-based asthma status ascertainment. Efficient inverse isoparametric mapping algorithm for whole-body computed tomography registration using deformations predicted by nonlinear finite element modeling.

Response of Escherichia coli growth rate to osmotic shock. A graph algebra for scalable visual analytics. Multiatlas segmentation as nonparametric regression. Coping with confounds in multivoxel pattern analysis: what should we do about reaction time differences? Automatic segmentation of head and neck CT images for radiotherapy treatment planning using multiple atlases, statistical appearance models, and geodesic active contours. Evaluating marker-guided treatment selection strategies.

Variations of dynamic contrast-enhanced magnetic resonance imaging in evaluation of breast cancer therapy response: a multicenter data analysis challenge. Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development. Knowledge-based fragment binding prediction. A complete system for automatic extraction of left ventricular myocardium from CT images using shape segmentation and contour evolution. Ensuring privacy in the study of pathogen genetics.

Mutual information as a measure of image quality for 3D dynamic lung imaging with EIT. Identifying regulatory mechanisms underlying tumorigenesis using locus expression signature analysis. Response to letters regarding article, "unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine". Population-level evidence for an autoimmune etiology of epilepsy. Joint modeling of imaging and genetics. Geodesic shape regression in the framework of currents.

Bayesian segmentation of atrium wall using globally-optimal graph cuts on 3D meshes. Group-wise cortical correspondence via sulcal curve-constrained entropy minimization. Sparse projections of medical images onto manifolds. A longitudinal functional analysis framework for analysis of white matter tract statistics. Aldosterone dysregulation with aging predicts renal vascular function and cardiovascular risk. Bayesian energy landscape tilting: towards concordant models of molecular ensembles.

Empirical Bayes methods enable advanced population-level analyses of single-molecule FRET experiments. Developing image processing meta-algorithms with data mining of multiple metrics. Cerebral white matter abnormalities and their associations with negative but not positive symptoms of schizophrenia. Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases.

Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma. High precision prediction of functional sites in protein structures. MAAMD: a workflow to standardize meta-analyses and comparison of affymetrix microarray data. Neuroinformatics challenges to the structural, connectomic, functional and electrophysiological multimodal imaging of human traumatic brain injury.

Changes in tibiofemoral forces due to variations in muscle activity during walking. Pregnancy in women with a history of Kawasaki disease: management and outcomes. Semantics in support of biodiversity knowledge discovery: an introduction to the biological collections ontology and related ontologies. The automated function prediction SIG looks back at and prepares for Automated detection of off-label drug use. Multifold Bayesian kernelization in Alzheimer's diagnosis.

Geodesic distances to landmarks for dense correspondence on ensembles of complex shapes. Systematic network lesioning reveals the core white matter scaffold of the human brain. Multi-atlas segmentation of subcortical brain structures via the AutoSeg software pipeline. SAVI: a statistical algorithm for variant frequency identification. On the mechanics of growing thin biological membranes. Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease.

Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes. When you can't tell when it hurts: a preliminary algorithm to assess pain in patients who can't communicate.

Crowdsourcing the verification of relationships in biomedical ontologies. Building and evaluating an ontology-based tool for reasoning about consent permission. Effects of polymerization and nucleotide identity on the conformational dynamics of the bacterial actin homolog MreB.

Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness. Annotating the structure and components of a nanoparticle formulation using computable string expressions. Rare copy number variation in treatment-resistant major depressive disorder. DTIPrep: quality control of diffusion-weighted images. Semi-Automatic Parcellation of the Corpus Striatum.

Validation of catheter segmentation for MR-guided gynecologic cancer brachytherapy. Contour-driven regression for label inference in atlas-based segmentation. Particle-guided image registration. Detecting epileptic regions based on global brain connectivity patterns. Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia.

Specificity of regulatory T cells that modulate vascular inflammation. Differential privacy based on importance weighting. Web-based tools for modelling and analysis of multivariate data: California ozone pollution activity. More accurate neuronavigation data provided by biomechanical modeling instead of rigid registration.

MutPred Splice: machine learning-based prediction of exonic variants that disrupt splicing. Word sense disambiguation in the clinical domain: a comparison of knowledge-rich and knowledge-poor unsupervised methods.

Automatic lymphoma classification with sentence subgraph mining from pathology reports. Regional neuroplastic brain changes in patients with chronic inflammatory and non-inflammatory visceral pain. A midas plugin to enable construction of reproducible web-based image processing pipelines. Serum inflammatory markers and risk of colorectal cancer in patients with inflammatory bowel diseases. A framework for longitudinal data analysis via shape regression. Fast approximate surface evolution in arbitrary dimension.

Studying PubMed usages in the field for complex problem solving: Implications for tool design. Atrial fibrillation ablation outcome is predicted by left atrial remodeling on MRI. Stochastic Image Registration with User Constraints. Fiber feature map based landmark initialization for highly deformable DTI registration. Quality Control of Diffusion Weighted Images. The environment ontology: contextualising biological and biomedical entities. Omnibus risk assessment via accelerated failure time kernel machine modeling.

Treatment response in kawasaki disease is associated with sialylation levels of endogenous but not therapeutic intravenous immunoglobulin G. Comorbidity clusters in autism spectrum disorders: an electronic health record time-series analysis. Mining the ultimate phenome repository. The neurological disease ontology. Discussion of ''Biomedical informatics: we are what we publish''. Amplification and thrifty single-molecule sequencing of recurrent somatic structural variations.

Genome-wide DNA methylation changes with age in disease free human skeletal muscle. Calculations of the electric fields in liquid solutions. Learning signals of adverse drug-drug interactions from the unstructured text of electronic health records.

Network analysis of unstructured EHR data for clinical research. Profiling risk factors for chronic uveitis in juvenile idiopathic arthritis: a new model for EHR-based research.

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. Associations of smoking and alcohol consumption with disease activity and functional status in rheumatoid arthritis. Predicting the restricted mean event time with the subject's baseline covariates in survival analysis.

Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia. Genetic robustness and functional evolution of gene duplicates. Three-dimensional treatment outcomes in Class II patients treated with the Herbst appliance: a pilot study. Chronology of your health events: approaches to extracting temporal relations from medical narratives.

OnTheFly: a database of Drosophila melanogaster transcription factors and their binding sites. SGPP: spatial Gaussian predictive process models for neuroimaging data. State of the human proteome in as viewed through PeptideAtlas: comparing the kidney, urine, and plasma proteomes for the biology- and disease-driven Human Proteome Project.

Reviewing the ketamine model for schizophrenia. Modeling disease severity in multiple sclerosis using electronic health records. Growing matter: a review of growth in living systems. Predictors of plasma and urinary catecholamine levels in normotensive and hypertensive men and women. Towards generating a patient's timeline: extracting temporal relationships from clinical notes.

Improved segmentation of white matter tracts with adaptive Riemannian metrics. In silico approaches and the role of ontologies in aging research. Using search queries for malaria surveillance, Thailand. Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome. Three-dimensional analysis of maxillary changes associated with facemask and rapid maxillary expansion compared with bone anchored maxillary protraction. Neuroimaging of structural pathology and connectomics in traumatic brain injury: Toward personalized outcome prediction.

Topology of viral evolution. Regional 3D superimposition to assess temporomandibular joint condylar morphology. Leveraging electronic health records to notify pediatric patients of a drug recall. Mining clinical text for signals of adverse drug-drug interactions. Application of universal stress proteins in probing the dynamics of potent degraders in complex terephthalate metagenome. Automated chart review for asthma cohort identification using natural language processing: an exploratory study.

Nocturnal continuous glucose and sleep stage data in adults with type 1 diabetes in real-world conditions. Human neuroimaging as a "Big Data" science. Distinct splice variants and pathway enrichment in the cell-line models of aggressive human breast cancer subtypes.

Localized Sparse Code Gradient in Alzheimer's disease staging. Conference proceedings Annual Conference. Nucleotide sequence alignment using sparse coding and belief propagation. Discovering body site and severity modifiers in clinical texts. Improved de-identification of physician notes through integrative modeling of both public and private medical text.

Temporal relation discovery between events and temporal expressions identified in clinical narrative. FMEM: functional mixed effects modeling for the analysis of longitudinal white matter Tract data. A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk. Neural encoding of acupuncture needling sensations: evidence from a FMRI study. Seasonality of Kawasaki disease: a global perspective.

Instrumentation bias in the use and evaluation of scientific software: recommendations for reproducible practices in the computational sciences. Automatic segmentation of the left atrium from MR images via variational region growing with a moments-based shape prior.

Combining an expert-based medical entity recognizer to a machine-learning system: methods and a case study. Opportunities for genomic clinical decision support interventions.

A novel strategy to identify the critical conditions for growth-induced instabilities. Temporomandibular joint condylar changes following maxillomandibular advancement and articular disc repositioning. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

Sex-related differences of cortical thickness in patients with chronic abdominal pain. On the design of clone-based haplotyping. A molecular signature predictive of indolent prostate cancer. Extraction of events and temporal expressions from clinical narratives. Tissue-specific profiling reveals transcriptome alterations in Arabidopsis mutants lacking morphological phenotypes.

Assessment of biomarkers for risk prediction with nested case-control studies. Electroencephalographic inverse localization of brain activity in acute traumatic brain injury as a guide to surgery, monitoring and treatment.

A new tool for sharing and querying of clinical documents modeled using HL7 Version 3 standard. Prostate cancer detection and diagnosis: the role of MR and its comparison with other diagnostic modalities--a radiologist's perspective. Automated skin segmentation in ultrasonic evaluation of skin toxicity in breast cancer radiotherapy. Using twitter to examine smoking behavior and perceptions of emerging tobacco products.

PhenDisco: phenotype discovery system for the database of genotypes and phenotypes. Virmid: accurate detection of somatic mutations with sample impurity inference. Identification of Functional Regulatory Residues of the? Automatic prediction of rheumatoid arthritis disease activity from the electronic medical records. On the effect of prestrain and residual stress in thin biological membranes.

Multimodal deformable registration of traumatic brain injury MR volumes via the Bhattacharyya distance. Toward a comprehensive framework for the spatiotemporal statistical analysis of longitudinal shape data. Identifying phenotypic signatures of neuropsychiatric disorders from electronic medical records. Classifying temporal relations in clinical data: A hybrid, knowledge-rich approach. Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders.

Mapping cortical atrophy in Parkinson's disease patients with dementia. Lipid and lipoprotein levels and trend in rheumatoid arthritis compared to the general population. Extending the NegEx lexicon for multiple languages. ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer. The integrated landscape of driver genomic alterations in glioblastoma.

Shape abnormalities of the caudate nucleus correlate with poorer gait and balance: results from a subset of the LADIS study. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Magnetic resonance microscopy-based analyses of the neuroanatomical effects of gestational day 9 ethanol exposure in mice. MedTime: a temporal information extraction system for clinical narratives. Syntactic parsing of clinical text: guideline and corpus development with handling ill-formed sentences. Immune-monitoring in Kawasaki disease patients treated with infliximab and intravenous immunoglobulin. A locally adaptive regularization based on anisotropic diffusion for deformable image registration of sliding organs.

Interactive medical image segmentation using PDE control of active contours. Localizing the human primary auditory cortex in vivo using structural MRI. Fast local trust region technique for diffusion tensor registration using exact reorientation and regularization. Annotating temporal information in clinical narratives. Semantator: Semantic annotator for converting biomedical text to linked data. From connectivity models to region labels: identifying foci of a neurological disorder.

Computational semantics in clinical text. Longitudinal image registration with temporally-dependent image similarity measure. Variants in exons and in transcription factors affect gene expression in trans.

Ground state destabilization by anionic nucleophiles contributes to the activity of phosphoryl transfer enzymes. Statistical shape modeling of cam femoroacetabular impingement. Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine.

Sarcomere lengths in human extensor carpi radialis brevis measured by microendoscopy. Inference of historical migration rates via haplotype sharing. Improving data and knowledge management to better integrate health care and research. Adopting nested case-control quota sampling designs for the evaluation of risk markers. Decreased axial diffusivity within language connections: A possible biomarker of schizophrenia risk. Sparse texture active contour. Computational modeling of chemo-electro-mechanical coupling: a novel implicit monolithic finite element approach.

Increased gray matter diffusion anisotropy in patients with persistent post-concussive symptoms following mild traumatic brain injury. Privacy technology to support data sharing for comparative effectiveness research: a systematic review. Long-term 3-dimensional stability of mandibular advancement surgery. Using Genome Query Language to uncover genetic variation.

Systematic improvement of a classical molecular model of water. Mechanical consequences of cell-wall turnover in the elongation of a Gram-positive bacterium. Forward and inverse electroencephalographic modeling in health and in acute traumatic brain injury. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology.

Automatic delineation of the myocardial wall from CT images via shape segmentation and variational region growing. Hypothalamic proteoglycan syndecan-3 is a novel cocaine addiction resilience factor.

Evaluating genome architecture of a complex region via generalized bipartite matching. Extracting physician group intelligence from electronic health records to support evidence based medicine.

Dynamic Active Contours for Visual Tracking. Spatial-temporal atlas of human fetal brain development during the early second trimester. Practice-based evidence: profiling the safety of cilostazol by text-mining of clinical notes. Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls.

A rolling constraint reproduces ground reaction forces and moments in dynamic simulations of walking, running, and crouch gait. Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway. Inferences on the biochemical and environmental regulation of universal stress proteins from Schistosomiasis parasites.

Impact of sex and gonadal steroids on neonatal brain structure. Morse-Smale Regression. Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America. A flexible framework for recognizing events, temporal expressions, and temporal relations in clinical text. Human middle longitudinal fascicle: segregation and behavioral-clinical implications of two distinct fiber connections linking temporal pole and superior temporal gyrus with the angular gyrus or superior parietal lobule using multi-tensor tractography.

Diffusion imaging quality control via entropy of principal direction distribution. Temporal reasoning over clinical text: the state of the art. Beyond NPM-anaplastic lymphoma kinase driven lymphomagenesis: alternative drivers in anaplastic large cell lymphoma. Improving breast cancer survival analysis through competition-based multidimensional modeling.

Reprever: resolving low-copy duplicated sequences using template driven assembly. HIV infection reveals widespread expansion of novel centromeric human endogenous retroviruses.

Surgery, virtual reality, and the future. Enhanced modeling via network theory: Adaptive sampling of Markov state models. Growth on demand: Reviewing the mechanobiology of stretched skin. Optical flow estimation for flame detection in videos. Genetic contributions to changes of fiber tracts of ventral visual stream in 22q Lateral ventricle morphology analysis via mean latitude axis.

On the mechanics of continua with boundary energies and growing surfaces. Combining rules and machine learning for extraction of temporal expressions and events from clinical narratives. Heterogeneity of tumor-induced gene expression changes in the human metabolic network.

Innovations in proteomic profiling of cancers: alternative splice variants as a new class of cancer biomarker candidates and bridging of proteomics with structural biology. Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer.

Dominant effects of the Huntington's disease HTT CAG repeat length are captured in gene-expression data sets by a continuous analysis mathematical modeling strategy. Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver.

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Towards improved ultrasound-based analysis and 3D visualization of the fetal brain using the 3D Slicer.

Eventual situations for timeline extraction from clinical reports. Seeing Ghosts , a memoir by Kat Chow. Grand Central Publishing hide caption.

In her memoir, Seeing Ghosts , the author and former Code Switch reporter explores how her mother's death has haunted her through the years, in ways that are profound, tragic and, sometimes, darkly hilarious.

But they're all students, they're all amazing, and frankly, we're concerned that they might be coming for our jobs. That's right — the Student Podcast Challenge is back, and this year, the stories are more powerful than ever. So in the spirit of spicing things up, we wanted to give you all a question to fight about: How much context should you have to give when talking about race and culture?

Is it better to explain every reference, or ask people to Google as they go? Comedian Hari Kondabolu joins us to hash it out. But there is so much police violence that falls short of being fatal, but forever alters the lives of the people on the business end of it. Helen Hoang, author of The Kiss Quotient. Eric Kieu hide caption. Today, we're in conversation with a romance novelist whose own identity helped inform a rich cast of characters. Somebody's Daughter , by Ashley C.

In her new memoir, Somebody's Daughter, Ford looks at how her upbringing shaped her understanding of childhood, authority, forgiveness and freedom. Accessibility links Skip to main content Keyboard shortcuts for audio player.

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